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ARS Home » Northeast Area » Ithaca, New York » Robert W. Holley Center for Agriculture & Health » Plant, Soil and Nutrition Research » People & Locations » Raymond Glahn
Raymond P Glahn
Plant, Soil and Nutrition Research
Research Physiologist (Animals)

Phone: (607) 255-2452
Fax: (607) 255-1132

(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)

Projects
Nutritional Quality and Micronutrient Bioavailability of Foods
Cooperative Agreement (A)
  Accession Number: 440158
Assessment of Bioavailable Iron from Staple Food Crops and Food Products: A Focus on Pulse Crops
In-House Appropriated (D)
  Accession Number: 445787
Collaborative Animal Research Between Cornell University and USDA-ARS
Non-Funded Cooperative Agreement (N)
  Accession Number: 440702

Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
Chemical composition and in vitro iron bioavailability of extruded and open-pan cooked germinated and ungerminated pearl whole millet “Pennisetum glaucum (L.) R. Br.” Reprint Icon - (Peer Reviewed Journal)
Theodoro, J., Da Silva, B., Grancieri, M., Oliveira, L., Glahn, R.P., De Carvalho, I., Lucia, C., Martino, H., Rostagno, M., Carvalho, C., Bragagnolo, F. 2024. Chemical composition and in vitro iron bioavailability of extruded and open-pan cooked germinated and ungerminated pearl whole millet “Pennisetum glaucum (L.) R. Br.”. Food Chemistry. 457C, 140170. https://doi.org/10.1016/j.foodchem.2024.140170.
Genome-wide association and genomic prediction for iron and zinc concentration and iron bioavailability in a collection of yellow dry beans Reprint Icon - (Peer Reviewed Journal)
Izquierdo, P., Sadohara, R., Wiesinger, J.A., Glahn, R.P., Urrea, C., Cichy, K.A. 2024. Genome-wide association and genomic prediction for iron and zinc concentration and iron bioavailability in a collection of yellow dry beans. Frontiers in Genetics. 15:13303361. https://doi.org/10.3389/fgene.2024.1330361.
Iron bioavailability of maize is improved by degermination for some but not all genotypes: enhancing maize nutrition with biofortification and processing Reprint Icon - (Peer Reviewed Journal)
Kiegler, J.I., Wiesinger, J.A., Flint Garcia, S.A., Glahn, R.P. 2023. Iron bioavailability of maize is improved by degermination for some but not all genotypes: enhancing maize nutrition with biofortification and processing. Frontiers in Sustainable Food Systems. vol. 14. https://doi.org/10.3389/fpls.2023.1114760.
Extrusion and drying temperatures enhance sensory profile and iron bioavailability of dry bean pasta Reprint Icon - (Peer Reviewed Journal)
Hooper, S.D., Basset, A., Wiesinger, J.A., Glahn, R.P., Cichy, K.A. 2023. Extrusion and drying temperatures enhance sensory profile and iron bioavailability of dry bean pasta. Food Chemistry Advances. (3):100422. https://doi.org/10.1016/j.focha.2023.100422.
Examination of the functional properties, protein quality, and iron bioavailability of low phytate pea protein ingredients Reprint Icon - (Peer Reviewed Journal)
Chigwedere, C., Stone, A., Konieczny, D., Lindsay, D., Huan, S., Glahn, R.P., House, J., Warkentin, T., Nickerson, M. 2023. Examination of the functional properties, protein quality, and iron bioavailability of low phytate pea protein ingredients. European Food Research and Technology. 249:1517-1529. https://doi.org/10.1007/s00217-023-04232-x.
Identifying genes associated with abiotic stress tolerance suitable for CRISPR/Cas9 editing in upland rice cultivars adapted to acid soils Reprint Icon - (Peer Reviewed Journal)
Barrero, L., William, M., Craft, E.J., Akther, K., Martinez, G., Glahn, R.P., Harrington, S., Pineros, M., Mccouch, S. 2022. Identifying genes associated with abiotic stress tolerance suitable for CRISPR/Cas9 editing in upland rice cultivars adapted to acid soils. Plant Direct. 6(12):Article e469. https://doi.org/10.1002/pld3.469.
The caco-2 cell bioassay for measurement of food iron bioavailability Reprint Icon - (Peer Reviewed Journal)
Glahn, R.P. 2022. The caco-2 cell bioassay for measurement of food iron bioavailability. The Journal of Visualized Experiments (JoVE). 182. Article e63859. https://doi.org/10.3791/63859.
The common bean V gene encodes flavonoid 3'5' hydroxylase: a major mutational target for flavonoid diversity in angiosperms Reprint Icon - (Peer Reviewed Journal)
Mclean, P.E., Lee, R., Howe, K.J., Osborne, C., Grimwood, J., Levy, S., Haugrud, A.P., Plott, C., Robinson, M., Skiba, R.M., Tanha, T., Zamani, M., Thannhauser, T.W., Glahn, R.P., Schmutz, J., Osorno, J., Miklas, P.N. 2022. The common bean V gene encodes flavonoid 3'5' hydroxylase: A major mutational target for flavonoid diversity in angiosperms. Frontiers in Plant Science. 13:869582. https://doi.org/10.3389/fpls.2022.869582.
Health implications and nutrient bioavailability of bioactive compounds in dry beans and other pulses Reprint Icon - (Book / Chapter)
Wiesinger, J.A., Marsolais, F., Glahn, R.P. 2022. Health implications and nutrient bioavailability of bioactive compounds. In: Siddiqu, M. and Uebersax, M. Dry Beans and Pulses Production, Processing and Nutrition. 2nd edition. Hoboken, NJ: John Wiley & Sons Ltd. p. 505-530.
Multi-year field evaluation of nicotianamine biofortified bread wheat Reprint Icon - (Peer Reviewed Journal)
Beasely, J.T., Bonneau, J.P., Moreno-Moyano, L.T., Callahan, D.L., Howell, K.S., Tako, E., Taylor, J., Glahn, R.P., Appels, R., Johnson, A.A. 2021. Multi-year field evaluation of nicotianamine biofortified bread wheat. Plant Journal. 109:1168-1182. https://doi.org/10.1111/tpj.15623.
Redefining bean iron biofortification: a review of the evidence for moving to a high Fe bioavailability approach - (Review Article)
Genetic control of iron bioavailability is independent from iron concentration in a diverse winter wheat mapping population Reprint Icon - (Peer Reviewed Journal)
Wright, T.I., Gardner, K., Glahn, R.P., Milner, M.J. 2021. Genetic control of iron bioavailability is independent from iron concentration in a diverse winter wheat mapping population. Biomed Central (BMC) Plant Biology. 21:212-225. https://doi.org/10.1186/s12870-021-02996-6.
Investigation of genotype by environment interactions for seed zinc and iron concentration and iron bioavailability in common bean Reprint Icon - (Peer Reviewed Journal)
Katuuramu, D.N., Wiesinger, J.A., Luyima, G.B., Nkalubo, S.T., Glahn, R.P., Cichy, K.A. 2021. Investigation of genotype by environment interactions for seed zinc and iron concentration and iron bioavailability in common bean. Frontiers in Plant Science. 12:670965. https://doi.org/10.3389/fpls.2021.670965.
Faster cooking times and improved iron bioavailability are associated with the down regulation of procyanidin synthesis in slow-darkening pinto beans (Phaseolus vulgaris L.) Reprint Icon - (Peer Reviewed Journal)
Wiesinger, J.A., Osorno, J.M., Mcclean, P.E., Hart, J.J., Glahn, R.P. 2021. Faster cooking times and improved iron bioavailability are associated with the down regulation of procyanidin synthesis in slow-darkening pinto beans (Phaseolus vulgaris L.). Journal of Functional Foods. 82:104444. https://doi.org/10.1016/j.jff.2021.104444.
Dual-fortified lentil products - a sustainable new approach to provide additional bioavailable iron and zinc in humans Reprint Icon - (Peer Reviewed Journal)
Podder, R., Glahn, R.P., Vandenberg, A. 2021. Dual-fortified lentil products - a sustainable new approach to provide additional bioavailable iron and zinc in humans. Current Developments in Nutrition. 01/30/2021.
Dry bean biofortification with iron and zinc Reprint Icon - (Book / Chapter)
Cichy, K.A., Chiu, C., Isaacs, K., Glahn, R.P. 2022. Dry bean biofortification with iron and zinc. In: Kumar, Shiv, Dikshit, Harsh Kumar, Mishra, Gyan Prakash, Singh, Akanksha, editors. Biofortification of Staple Crops. Singapore. Springer. p. 225-270. https://doi.org/10.1007/978-981-16-3280-8_10.
Iron and zinc fortified lentil (Lens culinaris Medik.) demonstrate enhanced and stable iron bioavailability after storage Reprint Icon - (Peer Reviewed Journal)
Podder, R., Glahn, R.P., Vandenberg, A. 2021. Iron and zinc fortified lentil (Lens culinaris Medik.) demonstrate enhanced and stable iron bioavailability after storage. Frontiers in Nutrition. 7:614812. https://doi.org/10.3389/fnut.2020.614812.
Effect of rice GDP-L-Galactose phosphorylase constitutive overexpression on ascorbate concentrations, stress tolerance, and iron bioavailability in rice Reprint Icon - (Peer Reviewed Journal)
Broad, R., Bonneau, J., Beasley, J., Roden, S., Sadowski, P., Berger, B., Tako, E., Glahn, R.P., Hellens, R., Johnson, A. 2020. Effect of rice GDP-L-Galactose phosphorylase constitutive overexpression on ascorbate concentrations, stress tolerance, and iron bioavailability in rice. Frontiers in Plant Science. https://doi.org/10.3389/fpls.2020.595439.
Impact of Ascorbic acid on the in vitro Iron Bioavailability of a casein-based Iron Fortificant in comparison to Ferrous Sulfate and Ferric Pyrophosphate Reprint Icon - (Peer Reviewed Journal)
Sabatier, M., Rytz, A., Dubascoux, S., Nicolas, M., Dave, A., Singh, H., Bodis, M., Glahn, R.P. 2020. Impact of Ascorbic acid on the in vitro Iron bioavailability of a casein-based iron fortificant in comparison to ferrous sulfate and ferric pyrophosphate. Nutrients. 12(9):2776. https://doi.org/10.3390/nu12092776.
Biofortified beans of East Africa are not significantly higher in iron content relative to non-biofortified marketplace varieties Reprint Icon - (Peer Reviewed Journal)
Glahn, R.P., Wiesinger, J.A., Lung'Aho, M. 2020. Biofortified beans of East Africa are not significantly higher in iron content relative to non-biofortified marketplace varieties. Journal of Nutrition. https://doi.org/10.1093/jn/nxaa193.
Processing white or yellow dry beans (phaseolus vulgaris L.) into a heat treated flour enhances the iron bioavailability of bean-based pastas Reprint Icon - (Peer Reviewed Journal)
Wiesinger, J.A., Cichy, K.A., Hooper, S., Hart, J.J., Glahn, R.P. 2020. Processing white or yellow dry beans (phaseolus vulgaris L.) into a heat treated flour enhances the iron bioavailability of bean-based pastas. Journal of Functional Foods. 71:104018.
Iron fortification and bioavailability of chickpea (Cicer arietinum L.) seeds and flour Reprint Icon - (Peer Reviewed Journal)
Jahan, T., Vandenberg, A., Glahn, R.P., Tyler, R.T., Reaney, M.J., Tar'An, B. 2019. Iron fortification and bioavailability of chickpea (Cicer arietinum L.) seeds and flour. Nutrients. 11(9):2240. https://doi.org/10.3390/nu11092240.
Iron bioavailability of fortified maize and sorghum porridges - (Peer Reviewed Journal)
Alandy, V., Fleige, L., Glahn, R.P. 2019. Iron bioavailability of fortified maize and sorghum porridges. Journal of Nutritional Health & Food Science. 7(3):1-6.
An In Vivo (Gallus gallus) Feeding Trial Demonstrating the Enhanced Iron Bioavailability Properties of the Fast Cooking Manteca Yellow Bean (Phaseolus vulgaris L.) Reprint Icon - (Peer Reviewed Journal)
Wiesinger, J.A., Glahn, R.P., Cichy, K.A., Kolba, N.J., Hart, J.J., Tako, E.N. 2019. An in vivo (Gallus gallus) feeding trial demonstrates the enhanced iron bioavailability properties of the fast cooking Manteca yellow bean (Phaseolus vulgaris L.). Nutrients. 11(8):1768. https://doi.org/10.3390/nu11081768.
Investigation of Nicotianamine and 2’ Deoxymugineic Acid as enhancers of iron bioavailability in Caco-2 cells Reprint Icon - (Peer Reviewed Journal)
Beasley, J., Johnaon, A., Glahn, R.P., Hart, J.J., Tako, E.N. 2019. Investigation of Nicotianamine and 2’ Deoxymugineic Acid as enhancers of iron bioavailability in Caco-2 cells. Nutrients. 11(7):1502. https://doi.org/10.3390/nu11071502.
Soluble extracts from carioca beans (Phaseolus vulgaris L.) affect the gut microbiota and iron related brush border membrane protein expression in vivo (Gallus gallus) Reprint Icon - (Peer Reviewed Journal)
Dias, D., Kolba, N.J., Nutti, M., Martino, H., Hart, J.J., Ma, M., Lakshmanan, N., Glahn, R.P., Sha, S., Tako, E.N. 2019. Soluble extracts from carioca beans (Phaseolus vulgaris L.) affect the gut microbiota and iron related brush border membrane protein expression in vivo (Gallus gallus). Food Research International. 123:172-180. https://doi.org/10.1016/j.foodres.2019.04.060.
Single varietal dry bean (Phaseolus vulgaris L.) pastas: Nutritional profile and consumer acceptability Reprint Icon - (Peer Reviewed Journal)
Hooper, S., Glahn, R.P., Cichy, K.A. 2019. Single varietal dry bean (Phaseolus vulgaris L.) pastas: Nutritional profile and consumer acceptability. Plant Foods for Human Nutrition. https://doi.org/10.1007/s11130-019-00732-y.
The germ fraction inhibits iron bioavailability of maize: identification of an approach to enhance maize nutritional quality via processing and breeding Reprint Icon - (Peer Reviewed Journal)
Glahn, R.P., Tako, E.N., Gore, M.A. 2019. The germ fraction inhibits iron bioavailability of maize: identification of an approach to enhance maize nutritional quality via processing and breeding. Nutrients. 11(4):833. https://doi.org/10.3390/nu11040833.
Seasonal trends of nutrient intake in rainforest communities of northeastern Madagascar Reprint Icon - (Peer Reviewed Journal)
Golden, C., Vaitla, B., Ravaoliny, L., Vonona, M., Anjaranirina, E., Randriamady, H., Guth, S., Fernald, L., Myers, S., Glahn, R.P. 2019. Seasonal trends of nutrient intake in rainforest communities of northeastern Madagascar. Public Health Nutrition. 12:2200-2209. https://doi.org/10.1017/S1368980019001083.
Metabolic engineering of bread wheat improves grain iron concentration and bioavailability Reprint Icon - (Peer Reviewed Journal)
Beasley, J., Bonneau, J., Sanchez-Palacious, J., Moreno-Moyano, L., Callahan, D., Tako, E.N., Glahn, R.P., Lombi, E., Johnson, A. 2019. Metabolic engineering of bread wheat improves grain iron concentration and bioavailability. Plant Biotechnology Journal. 17(8):1514-1526. https://doi.org/10.1111/pbi.13074.
Iron biofortified carioca bean (phaseolus vulgaris l.) —based Brazilian diet delivers more absorbable iron and affects the gut microbiota in vivo (gallus gallus) Reprint Icon - (Peer Reviewed Journal)
Morais Dias, D., Kolba, N.J., Binyamin, D., Ziv, O., Regini Nutti, M., Stampini Duarte, M., Glahn, R.P., Koren, O., Tako, E.N. 2018. Iron biofortified carioca bean (phaseolus vulgaris l.) —based Brazilian diet delivers more absorbable iron and affects the gut microbiota in vivo (gallus gallus). Nutrients. 10(12):1970. https://doi.org/10.3390/nu10121970.
The fast cooking and enhanced iron bioavailability properties of the manteca yellow bean (Phaseolus vulgaris L.) Reprint Icon - (Peer Reviewed Journal)
Wiesinger, J.A., Cichy, K.A., Tako, E.N., Glahn, R.P. 2018. The fast cooking and enhanced iron bioavailability properties of the manteca yellow bean (Phaseolus vulgaris L.). Nutrients. 10(11):1609. https://doi.org/10.3390/nu10111609.
Alterations in the gut (Gallus gallus) microbiota following the consumption of zinc biofortified wheat (Triticum aestivum) -based diet Reprint Icon - (Peer Reviewed Journal)
Reed, S., Knez, M., Uzan, A., Stangoulis, J., Glahn, R.P., Koren, O., Tako, E.N. 2018. Alterations in the gut (Gallus gallus) microbiota following the consumption of zinc biofortified wheat (Triticum aestivum) -based diet. Journal of Agricultural and Food Chemistry. 66(25):6291-6299. https://doi.org/10.1021/acs.jafc.8b01481.
Iron bioavailability from multiple biofortified foods using an in vitro digestion, Caco-2 assay for optimizing a cyclical menu for a randomized efficacy trial (P10-029-19) Reprint Icon - (Peer Reviewed Journal)
Gannon, B., Glahn, R.P., Mehta, S. 2019. Iron bioavailability from multiple biofortified foods using an in vitro digestion, Caco-2 assay for optimizing a cyclical menu for a randomized efficacy trial (P10-029-19). Current Developments in Nutrition. 3(1). https://doi.org/10.1093/cdn/nzz034.P10-029-19.
Development of a fortified juice beverage: assessment of iron bioavailability using an established caco-2 cell bioassay Reprint Icon - (Peer Reviewed Journal)
Fleige, L., Bhoite, R., Marwaha, A., Glahn, R.P. 2018. Development of a fortified juice beverage: assessment of iron bioavailability using an established caco-2 cell bioassay. Journal of Nutrition & Food Sciences. 6(3):1-7. https://doi.org/10.15226/jnhfs.2018.001133.
Evaluation of selected ultra-trace minerals in commercially available dry dog foods Reprint Icon - (Peer Reviewed Journal)
Wakshlag, J., Glahn, R.P., Kim, H., Loftus, J., Gagne, J., Rutzke, M. 2018. Evaluation of selected ultra-trace minerals in commercially available dry dog foods. Veterinary Medicine: Research and Reports. 9:43-51. https://doi.org/10.2147/VMRR.S165890.
Relative bioavailability of iron in Bangledeshi traditional meals prepared with iron-fortified lentil dal Reprint Icon - (Peer Reviewed Journal)
Podder, R., Dellavalle, D., Tyler, R., Glahn, R.P., Tako, E.N., Vandenberg, A. 2018. Relative bioavailability of iron in Bangledeshi traditional meals prepared with iron-fortified lentil dal. Nutrients. 10(3). https://doi.org/10.3390/nu10030354.
The linoleic acid: dihomo-y-linolenic acid ratio predicts the efficacy of Zn biofortified wheat in chicken (Gallus gallus) Reprint Icon - (Peer Reviewed Journal)
Tako, E.N., Knez, M., Kolba, N.J., Glahn, R.P., Ireland, E., Stangoulis, J. 2018. The linoleic acid: dihomo-y-linolenic acid ratio predicts the efficacy of Zn biofortified wheat in chicken (Gallus gallus). Journal of Agricultural and Food Chemistry. 66(6):1394-1400. http://doi.org/10.1021/acs.jafc.7b04905.
Iron bioavailability studies of the first generation of iron-biofortified beans released in Rwanda Reprint Icon - (Book / Chapter)
Glahn, R.P., Hart, J.J., Beebe, S., Tako, E.N. 2018. Iron bioavailability studies of the first generation of iron-biofortified beans released in Rwanda. In: Tako, E., editor. Fe deficiency, dietary bioavailability and absorption. Basel, Switzerland: MDPI Books. p. 16-27. https://doi.org/10.3390/books978-3-03897-231-0.
Physico-chemical properties, phytochemicals and antioxidant activity of supercritical fluid extruded lentils Reprint Icon - (Peer Reviewed Journal)
Yv, Y., Glahn, R.P., Hebb, R., S.H. Rizvi, S. 2017. Physico-chemical properties, phytochemicals and antioxidant activity of supercritical fluid extruded lentils. LWT - Food Science and Technology. 89:315-321. https://doi.org/10.1016/j.lwt.2017.10.063.
Physico-chemical properties, phytochemicals and DPPH radical scavenging activity of supercritical fluid extruded lentils Reprint Icon - (Peer Reviewed Journal)
Ying, L., Glahn, R.P., Hebb, R., Rizvi, S. 2017. Physico-chemical properties, phytochemicals and DPPH radical scavenging activity of supercritical fluid extruded lentils. LWT - Food Science and Technology. 89:315-321. https://doi.org/10.1016/j.lwt.2017.10.063.
Intra-amniotic administration (Gallus gallus) of cicer arietinum and lens culinaris prebiotics extracts and duck egg white peptides affects calcium status and intestinal functionality - (Peer Reviewed Journal)
Hou, T., Kolba, N.J., Glahn, R.P., Tako, E. 2017. Intra-amniotic administration (Gallus gallus) of cicer arietinum and lens culinaris prebiotics extracts and duck egg white peptides affects calcium status and intestinal functionality. Nutrients. 9(7):785. doi:10.3390/nu9070785.
Characterizing the gut (Gallus gallus) microbiota following the consumption of an iron biofortified Rwandan cream seeded carioca (Phaseolus Vulgaris L.) bean-based diet - (Peer Reviewed Journal)
Reed, S., Neuman, H., Glahn, R.P., Omry, K., Tako, E.N. 2017. Characterizing the gut (Gallus gallus) microbiota following the consumption of an iron biofortified Rwandan cream seeded carioca (Phaseolus Vulgaris L.) bean-based diet. PLoS One. 12(8):e0182431. https://doi.org/10.1371/journal.pone.0182431.
Iron bioavailability studies of the first generation of iron-biofortified beans released in Rwanda - (Peer Reviewed Journal)
Glahn, R.P., Tako, E., Hart, J.J., Haas, J., Lung'Aho, M., Beebe, S. 2017. Iron bioavailability studies of the first generation of iron-biofortified beans released in Rwanda. Nutrients. 9(7):787.
Characterization of polyphenol effects on inhibition and promotion or iron update by caco-2 cells - (Peer Reviewed Journal)
Hart, J.J., Tako, E.N., Glahn, R.P. 2017. Characterization of polyphenol effects on inhibition and promotion or iron update by caco-2 cells. Journal of Agricultural and Food Chemistry. 65(16):3285-3294.
Intra amniotic administration of raffinose and stachyose affects the intestinal brush border functionality and alters gut microflora populations - (Peer Reviewed Journal)
Pacifici, S., Song, J., Zhang, C., Wang, Q., Glahn, R.P., Kolba, N.J., Tako, E.N. 2017. Intra amniotic administration of raffinose and stachyose affects the intestinal brush border functionality and alters gut microflora populations. Nutrients. 9(3):304. doi:10.3390/nu9030304.
Zinc and selenium accumulation and their effect on iron bioavailability in common bean seeds - (Peer Reviewed Journal)
Figueiredo, M.A., Boldrin, P.F., Hart, J.J., Andrade, M., Guilherme, L., Glahn, R.P., Li, L. 2017. Zinc and selenium accumulation and their effect on iron bioavailability in common bean seeds. Plant Physiology and Biochemistry. 111:193-202.
The combined application of the Caco-2 cell bioassay coupled with in vivo (Gallus gallus) feeding trial represents an effective approach to predicting Fe bioavailability in humans - (Peer Reviewed Journal)
Tako, E.N., Bar, H., Glahn, R.P. 2016. The combined application of the Caco-2 cell bioassay coupled with in vivo (Gallus gallus) feeding trial represents an effective approach to predicting Fe bioavailability in humans. Nutrients. 8(11):732.
Demonstrating a nutritional advantage to the fast cooking dry bean (Phaseolus vulgaris L.) - (Peer Reviewed Journal)
Wiesinger, J.A., Cichy, K.A., Glahn, R.P., Grusak, M.A., Brick, M., Thompson, H., Tako, E.N. 2016. Demonstrating a nutritional advantage to the fast cooking dry bean (Phaseolus vulgaris L.). Journal of Agricultural and Food Chemistry. 64(45):8592-8603.
A novel in vivo model for assessing the impact of geophagic earth on iron status - (Peer Reviewed Journal)
Siem, G., Tako, E.N., Ahn, C., Bodis, M., Glahn, R.P., Young, S. 2016. A novel in vivo model for assessing the impact of geophagic earth on iron status. Nutrients. 8(6):E362. doi:10.3390/nu8060362.
The cotyledon cell wall of the common bean (phaseolus vulgaris) resists digestion in the upper intestine and thus may limit iron bioavailability - (Peer Reviewed Journal)
Glahn, R.P., Tako, E.N., Cichy, K.A., Wiesinger, J.A. 2016. The cotyledon cell wall of the common bean (phaseolus vulgaris) resists digestion in the upper intestine and thus may limit iron bioavailability. Food & Function. 7(7):3193-3200.
Biofortified indica rice attains iron and zinc nutrition dietary targets in the field Reprint Icon - (Peer Reviewed Journal)
Trijatmiko, K.R., Duenas, C., Torrizo, L., Oliva, N., Francisco, P., Mae Arines, F., Adeva, C., Balindong, J., Sapasap, V., Barry, G., Slamet-Loedin, I.H., Lombi, E., Stangoulis, J., Johnson, A., Tako, E.N., Glahn, R.P. 2016. Biofortified indica rice attains iron and zinc nutrition dietary targets in the field. Scientific Reports. 6:19792.
Chronic zinc deficiency alters chick gut microbiota composition and function Reprint Icon - (Peer Reviewed Journal)
Reed, S.M., Neuman, H., Moskovitch, S., Glahn, R.P., Koren, O., Tako, E.N. 2015. Chronic zinc deficiency alters chick gut microbiota composition and function. Nutrients. 7:1-17.
Iron bioavailability in low phytate pea - (Peer Reviewed Journal)
Liu, X., Glahn, R.P., Arganosa, G.C., Warkentin, T.D. 2014. Iron bioavailability in low phytate pea. Crop Science. 55(1):320-330.
Extrinsic labelling of staple food crops with isotopic iron does not consistently result in full equilibration: Revisiting the methodology - (Peer Reviewed Journal)
Glahn, R.P., Cheng, Z., Giri, S. 2015. Extrinsic labelling of staple food crops with isotopic iron does not consistently result in full equilibration: Revisiting the methodology. Journal of Agricultural and Food Chemistry. 63(43):9621-9628.
Studies of cream seeded carioca beans (phaseolus vulgaris L.) from a Rwandan efficacy trial: in vitro and in vivo screening tools reflect human studies and predict beneficial results from iron biofortified beans - (Peer Reviewed Journal)
Tako, E.N., Reed, S.M., Anandaraman, A., Hart, J.J., Beebe, S.E., Glahn, R.P. 2015. Studies of cream seeded carioca beans (phaseolus vulgaris L.) from a Rwandan efficacy trial: in vitro and in vivo screening tools reflect human studies and predict beneficial results from iron biofortified beans. PLoS One. DOI: 10.1371/journal.pone.0138479.
Iron absorption from intrinsically-labeled lentils - (Peer Reviewed Journal)
Della Valle, D.M., Glahn, R.P., Shaff, J., O'Brien, K.O. 2015. Iron absorption from intrinsically-labeled lentils. Journal of Nutrition. DOI: 10.3945/jn.115.217273.
Identification of black bean (Phaseolus vulgaris L.) polyphenols that inhibit and promote iron uptake by caco-2 cells - (Peer Reviewed Journal)
Hart, J.J., Tako, E.N., Kochian, L.V., Glahn, R.P. 2015. Identification of black bean (Phaseolus vulgaris L.) polyphenols that inhibit and promote iron uptake by caco-2 cells. Journal of Agricultural and Food Chemistry. DOI: 10.1021/acs.jafc.5b00531.
A Phaseolus vulgaris diversity panel for Andean bean improvement - (Peer Reviewed Journal)
Cichy, K.A., Porch, T.G., Beaver, J.S., Cregan, P.B., Fourie, D., Glahn, R.P., Grusak, M.A., Kamfwa, K., Katuuramu, D., McClean, P., Mndolwa, E., Nchimbi-Msolla, S., Pastor Corrales, M.A., Miklas, P.N. 2015. A Phaseolus vulgaris diversity panel for Andean bean improvement. Crop Science. 55:2149-2160.
Higher iron pearl millet (Pennisetum glaucum L.) provides more absorbable iron that is limited by increased polyphenolic content - (Peer Reviewed Journal)
Tako, E.N., Reed, S.M., Budiman, J., Hart, J.J., Glahn, R.P. 2015. Higher iron pearl millet (Pennisetum glaucum L.) provides more absorbable iron that is limited by increased polyphenolic content. Nutrition Journal. 14:11.
Alterations in gut microflora populations and brush border functionality following intra-amniotic daidzein administration - (Peer Reviewed Journal)
Hortono, K., Reed, S.M., Ankrah, A., Glahn, R.P., Tako, E.N. 2014. Alterations in gut microflora populations and brush border functionality following intra-amniotic daidzein administration. RSC Advances. 5:6407-6412.
Differences in relative bioavailability of traditional Bangladeshi meal plans - (Peer Reviewed Journal)
Dellavalle, D.M., Glahn, R.P. 2014. Differences in relative bioavailability of traditional Bangladeshi meal plans. Food and Nutrition Bulletin. 35(4):431-439.
The effect of wheat prebiotics on the gut bacterial population and iron status of iron deficient broiler chickens - (Peer Reviewed Journal)
Tako, E.N., Marija, K., Glahn, R.P., Stangoulis, J. 2014. The effect of wheat prebiotics on the gut bacterial population and iron status of iron deficient broiler chickens. Nutrition Journal. 13:58.
Hydrolysis of soybean protein improves iron bioavailability - (Peer Reviewed Journal)
Lv, Y., Shuntang, G., Zhiqiang, C., Glahn, R.P., Tako, E.N. 2014. Hydrolysis of soybean protein improves iron bioavailability. Food and Nutrition Research. 2(4):162-166. DOI: 10.12691/jfnr-2-4-5.
Polyphenolic compounds appear to limit the nutritional benefit of biofortified higher iron black bean (phaseolus vulgaris L.) - (Peer Reviewed Journal)
Tako, E.N., Beebe, S.E., Hart, J.J., Reed, S.M., Glahn, R.P. 2014. Polyphenolic compounds appear to limit the nutritional benefit of biofortified higher iron black bean (phaseolus vulgaris L.). Nutrition Journal. 13:28.
Dietary zinc deficiency affects blood linoleic acid: dihomo-gamma-linolenic acid (LA:DGLA) ratio; a reactive physiological marker of zinc status in vivo (Gallus gallus) - (Peer Reviewed Journal)
Reed, S., Xia, Q., Rinat, R., Thomas, B., Glahn, R.P., Tako, E. 2014. Dietary zinc deficiency affects blood linoleic acid: dihomo-gamma-linolenic acid (LA:DGLA) ratio; a reactive physiological marker of zinc status in vivo (Gallus gallus). Nutrients. 6:1164-1180. DOI: 10.3390/nu6031164.
Seed coat removal improves Fe bioavailability in cooked lentils: studies using an in vitro digestion/Caco-2 cell culture model - (Peer Reviewed Journal)
DellaValle, D.M., Vandenberg, A., Glahn, R.P. 2013. Seed coat removal improves Fe bioavailability in cooked lentils: studies using an in vitro digestion/Caco-2 cell culture model. Journal of Agricultural and Food Chemistry. 61(34):8084-8089. DOI: 10.1021/jf4022916.
Evaluation of calcium, phosphorus, and selected trace mineral status in commercially available dry foods formulated for dogs - (Peer Reviewed Journal)
Bioavailability of iron in geophagic earths and clay minerals, and their effect on dietary iron absorption using an in vitro digestion/Caco-2 cell model Reprint Icon - (Peer Reviewed Journal)
Seim, G., Ahn, C.I., Bodis, M., Luwedde, F., Miller, D., Hillier, S., Tako, E.N., Glahn, R.P., Young, S.L. 2013. Bioavailability of iron in geophagic earths and clay minerals, and their effect on dietary iron absorption using an in vitro digestion/Caco-2 cell model. Food and Function. 4(8):1263-1270.
Soil consumed by chacma baboons is low in bioavailable iron and high in clay - (Peer Reviewed Journal)
Pebsworth, P.A., Seim, G., Huffman, M.A., Glahn, R.P., Tako, E.N., Young, S.L. 2013. Soil consumed by chacma baboons is low in bioavailable iron and high in clay. Journal of Chemical Ecology. http://www.springerlink.com/openurl.asp?genre=article&id=DOI: 10.1007/s10886-013-0258-3.
Lentil (Lens culinaris L) as a candidate crop for iron biofortification: Is there a genetic potential for iron bioavailability? - (Peer Reviewed Journal)
DellaValle, D.M., Thavarajah, D., Thavarajah, P., Vandenberg, A., Glahn, R.P. 2013. Lentil (Lens culinaris L) as a candidate crop for iron biofortification: Is there a genetic potential for iron bioavailability? Field Crops Research. 144:119-125.
High bioavailable iron maize (Zea mays L.) developed through molecular breeding provides more absorbable iron in vitro and in vivo - (Peer Reviewed Journal)
Tako, E.N., Hoekenga, O., Kochian, L.V., Glahn, R.P. 2013. High bioavailable iron maize (Zea mays L.) developed through molecular breeding provides more absorbable iron in vitro and in vivo. Nutrition Journal. 12:3.
Oral exposure to polystyrene nanoparticles effects iron absorption - (Peer Reviewed Journal)
Mahler, G., Esch, M., Tako, E.N., Southard, T., Glahn, R.P., Shuler, M. 2012. Oral exposure to polystyrene nanoparticles effects iron absorption. Nature Nanotechnology. DOI: 10.1038/nnano.2012.3.
Genetic reduction of antinutrients in common bean (Phaseolus vulgaris L.) seed, increases nutrients and in vitro iron bioavailability without depressing main agronomical traits - (Peer Reviewed Journal)
Campion, B., Glahn, R.P., Tava, A., Perrone, D., Doria, E., Sparvoli, F. 2013. Genetic reduction of antinutrients in common bean (Phaseolus vulgaris L.) seed, increases nutrients and in vitro iron bioavailability without depressing main agronomical traits. Field Crops Research. 141:27-37.
Evaluation of metallothionein formation as a proxy for zinc absorption in an in vitro digestion/caco-2 cell culture model - (Peer Reviewed Journal)
Zhiqiang, C., Tako, E.N., Yeung, A., Welch, R., Glahn, R.P. 2012. Evaluation of metallothionein formation as a proxy for zinc absorption in an in vitro digestion/caco-2 cell culture model. Food and Function. 3(7):732-736.
Intra amniotic administration and dietary inulin affect the iron status and intestinal functionality of iron deficient broiler chickens - (Peer Reviewed Journal)
Tako, E.N., Glahn, R.P. 2012. Intra amniotic administration and dietary inulin affect the iron status and intestinal functionality of iron deficient broiler chickens. Poultry Science. 91(6):1361-1370.
Metacridamides A and B, bioactive macrocycles from conidia of the entomopathogenic fungus Metarhizium acridum - (Peer Reviewed Journal)
Krasnoff, S., Englich, U., Miller, P.G., Shuler, M.L., Glahn, R.P., Donzelli, B.G., Gibson, D.M. 2012. Metacridamides A and B, bioactive macrocycles from conidia of the entomopathogenic fungus Metarhizium acridum. Journal of Natural Products. 75:175-180.
Biofortified red mottled beans (phaseolus vulgaris L.) in a maize and bean diet provide more bioavailable iron than standard red mottled beans: studies in poultry (Gallus gallus) and an in vitro digestion/Caco-2 model - (Peer Reviewed Journal)
Tako, E.N., Blair, M., Glahn, R.P. 2011. Biofortified red mottled beans (phaseolus vulgaris L.) in a maize and bean diet provide more bioavailable iron than standard red mottled beans: studies in poultry (Gallus gallus) and an in vitro digestion/Caco-2 model. Nutrition Journal. 10:113.
Metacridamides A and B from the biocontrol fungus metarhizium acridum - (Abstract Only)
Krasnoff, S., Englich, U., Miller, P., Shuler, M.L., Glahn, R.P., Donzelli, B.G., Gibson, D.M. 2011. Metacridamides A and B from the biocontrol fungus metarhizium acridum. American Society of Pharmacognosy. p. 325.
Iron status of the late term broiler (Gallus gallus) embryo and hatchling - (Peer Reviewed Journal)
Tako, E.N., Glahn, R.P. 2011. Iron status of the late term broiler (Gallus gallus) embryo and hatchling. International Journal of Poultry Science. 10(1):42-48.
The usefulness of iron bioavailability as a target for breeding maize (Zea mays L.) with enhanced nutritional value - (Peer Reviewed Journal)
Pixley, K., Glahn, R.P., Palacious-Rojas, N. 2011. The usefulness of iron bioavailability as a target for breeding maize (Zea mays L.) with enhanced nutritional value. Field Crops Research. 123(2)153:160.
Genetic and physiological analysis of iron content and bioavailability in maize kernels - (Peer Reviewed Journal)
Lung'Aho, M., Mwaniki, A., Szalma, S.J., Hart, J., Rutzke, M., Kochian, L.V., Glahn, R.P., Hoekenga, O. 2011. Genetic and physiological analysis of iron content and bioavailability in maize kernels. PLoS One. 6(6):e20429. DOI:10.1371/journal.pone.0020429.
The potential of lentil (Lens culinaris L.) as a whole food for increased selenium, iron, and zinc intake: Preliminary results from a three year study - (Peer Reviewed Journal)
Thavarajah, D., Thavarajah, P., Wejesuriya, A., Rutzke, M., Glahn, R.P., Combs, G.F., Vandenberg, A. 2011. The potential of lentil (Lens culinaris L.) as a whole food for increased selenium, iron, and zinc intake: Preliminary results from a three year study. Euphytica. 180(1):123-128.
Iron biofortification of maize grain - (Peer Reviewed Journal)
Hoekenga, O., Lung'Aho, M., Tako, E., Kochian, L.V., Glahn, R.P. 2011. Iron biofortification of maize grain. Plant Genetic Resources: Characterization and Utilization. 1-3. Available: http://journals.cambridge.org/
White beans provide more bioavailable iron than red beans: studies in poultry (Gallus gallus) and an in vitro digestion/Caco-2 model - (Peer Reviewed Journal)
Tako, E.N., Glahn, R.P. 2010. White beans provide more bioavailable iron than red beans: studies in poultry (Gallus gallus) and an in vitro digestion/Caco-2 model. International Journal for Vitamin and Nutrition Research. 80(6)416:429.
Using the domestic chicken (Gallus gallus) as an in vivo model for iron bioavailability - (Peer Reviewed Journal)
Tako, E., Rutzke, M.A., Glahn, R.P. 2010. Using the domestic chicken (Gallus gallus) as an in vivo model for iron bioavailability. Poultry Science. 89:514:521.
Use of White Bean Instead of Red Bean May Improve Iron Bioavailability from a Tanzanian Complementary Food Mixture - (Peer Reviewed Journal)
Lung'Aho, M.G., Glahn, R.P. 2010. Use of White Bean Instead of Red Bean May Improve Iron Bioavailability from a Tanzanian Complementary Food Mixture. International Journal for Vitamin and Nutrition Research. 80(1):24-31.
Different responses of Fe transporters in Caco2/HT29-MTX cocultures than in independent Caco-2 cell cultures - (Peer Reviewed Journal)
Laparra, J., Glahn, R.P., Miller, D. 2009. Different responses of Fe transporters in Caco2/HT29-MTX cocultures than in independent Caco-2 cell cultures. Cell Biology International. 33(9):971-977.
Dietary inulin supplementation does not promote colonic iron absorption in a porcine model - (Peer Reviewed Journal)
Patterson, J., Rutzke, M.A., Fubini, S.L., Glahn, R.P., Welch, R.M., Lei, X., Miller, D.D. 2009. Dietary inulin supplementation does not promote colonic iron absorption in a porcine model. Journal of Agricultural and Food Chemistry. 57(12):5250-5256.
Characterization of a gastrointestinal tract microscale cell culture analog used to predict drug toxicity - (Peer Reviewed Journal)
Mahler, G., Esch, M.B., Glahn, R.P., Shuler, M.L. 2009. Characterization of a gastrointestinal tract microscale cell culture analog used to predict drug toxicity. Biotechnology and Bioengineering. 104(1):193-205.
Approaching the cellular processes involved in the positive effect of glycosaminoglycans on Fe uptake to Caco-2 cells - (Peer Reviewed Journal)
Comparing soluble ferric pyrophosphate to common iron salts and chelates as sources of bioavailable iron in a caco-2 cell culture model - (Peer Reviewed Journal)
Zhu, L., Glahn, R.P., Nelson, D., Miller, D.D. 2009. Comparing soluble ferric pyrophosphate to common iron salts and chelates as sources of bioavailable iron in a caco-2 cell culture model. Journal of Agricultural and Food Chemistry. 57(11):5014-5019.
Purified glycosaminoglycans from cooked haddock may enhance Fe uptake via endocytosis in a Caco-2 cell culture model - (Peer Reviewed Journal)
Laparra, J., Barbera, R., Alegria, A., Glahn, R.P., Miller, D.D. 2009. Purified glycosaminoglycans from cooked haddock may enhance Fe uptake via endocytosis in a Caco-2 cell culture model. Journal of Food Science. 74(6):H168-173.
Iron and zinc bioavailabilities to pigs from red and white beans (Phaseolus vulgaris L.) are similar - (Peer Reviewed Journal)
Tako, E., Glahn, R.P., Laparra, J.M., Welch, R.M., Lei, X., Kelly, J.D., Rutzke, M.A., Miller, D.D. 2009. Iron and zinc bioavailabilities to pigs from red and white beans (Phaseolus vulgaris L.) are similar. Journal of Agricultural and Food Chemistry. 57(8):3134-3140.
Iron biofortification of maize grain - (Abstract Only)
Hoekenga, O., Lung'Aho, M., Kochian, L.V., Glahn, R.P. 2009. Iron biofortification of maize grain. [abstract]. 51st Annual Maize Genetics Conference.
The use of caco-2 cells in defining nutrient bioavailability: application to iron bioavailability of foods - (Book / Chapter)
Glahn, R.P. 2009. The use of caco-2 cells in defining nutrient bioavailability: application to iron bioavailability of foods. In: McClements, D., Decker, E. Designing functional foods: measuring and controlling food structure breakdown and nutrient absorption. Cambridge, UK: Woodhead Publishing Limited. p. 340-361.
In vitro estimates of iron bioavailability in some Kenyan complementary foods - (Peer Reviewed Journal)
Lung'Aho, M.G., Glahn, R.P. 2009. In vitro estimates of iron bioavailability in some Kenyan complementary foods. Food and Nutrition Bulletin. 30(2):145-152.
Effects of Tea Phenolics on Iron Uptake from Different Fortificants by Caco-2 cells - (Peer Reviewed Journal)
Laparra, J., Glahn, R.P., Miller, D.D. 2009. Effects of Tea Phenolics on Iron Uptake from Different Fortificants by Caco-2 cells. Food Chemistry. 115(3):974-981.
Milk peptides increase iron solubility in water but do not affect DMT-1 expression in Caco-2 cells - (Peer Reviewed Journal)
Argyri, K., Tako, E., Miller, D., Glahn, R.P., Komaitis, M., Kapsokefalou, M. 2009. Milk peptides increase iron solubility in water but do not affect DMT-1 expression in Caco-2 cells. Journal of Agricultural and Food Chemistry. 57(4):1538-1543.
Biofortified black beans (Phaseolus vulgaris L.) in a maize/bean diet provide more bioavailable iron to piglets than standard black beans - (Peer Reviewed Journal)
Tako, E., Laparra, J., Glahn, R.P., Welch, R.M., Lei, X., Beebe, S., Miller, D.D. 2009. Biofortified black beans (Phaseolus vulgaris L.) in a maize/bean diet provide more bioavailable iron to piglets than standard black beans. Journal of Nutrition. 139(2):417-422.
Serum hepcidin is significantly associated with iron absorption from food and supplemental sources in healthy young woman - (Peer Reviewed Journal)
Young, M.F., Glahn, R.P., Ariza-Nieto, M. 2009. Serum hepcidin is significantly associated with iron absorption from food and supplemental sources in healthy young woman. American Journal of Clinical Nutrition. 89(2):533-538.
Assesing potential effects of inulin and probiotic bacteria on Fe bioavailability from common beans (Phaseolus vulgaris L.) to Caco-2 cells - (Peer Reviewed Journal)
Laparra, J., Glahn, R.P., Miller, D. 2009. Assesing potential effects of inulin and probiotic bacteria on Fe bioavailability from common beans (Phaseolus vulgaris L.) to Caco-2 cells. Journal of Food Science. 74(2):H40-46.
Bioaccessibility of phenols in common beans (Phaseolus vulgaris L.) and iron (Fe) availability to Caco-2 cells - (Peer Reviewed Journal)
Laparra, J., Glahn, R.P., Miller, D.D. 2008. Bioaccessibility of phenols in common beans (Phaseolus vulgaris L.) and iron (Fe) availability to Caco-2 cells. Journal of Agricultural and Food Chemistry. 56(22):10999-11005.
CHICKEN THIGH, CHICKEN LIVER AND IRON-FORTIFIED WHEAT FLOUR OPTIMIZE IRON UPTAKE IN AN INVITRO DIGESTION/CACO-2 CELL MODEL - (Peer Reviewed Journal)
Pachon, H., Stoltzfus, R., Glahn, R.P. 2008. CHICKEN THIGH, CHICKEN LIVER AND IRON-FORTIFIED WHEAT FLOUR OPTIMIZE IRON UPTAKE IN AN INVITRO DIGESTION/CACO-2 CELL MODEL. Nutrition Research. 28(12):851-858.
Isolated Glycosaminoglycans from Cooked Haddock Enhance Nonheme Iron Uptake by Caco-2 cells - (Peer Reviewed Journal)
Laparra, J.M., Tako, E., Glahn, R.P., Miller, D. 2008. Isolated Glycosaminoglycans from Cooked Haddock Enhance Nonheme Iron Uptake by Caco-2 cells. Journal of Agricultural and Food Chemistry. 56(21):10346-10351.
Effects of Ascorbic Acid, Phytic Acid and Tannic Acid on Iron Bioavailability from Reconstituted Ferritin Measured by an In Vitro Digestion/Caco-2 Cell Model - (Peer Reviewed Journal)
Jin, F., Frohman, C., Glahn, R.P., Thannhauser, T.W., Welch, R.M. 2009. Effects of Ascorbic Acid, Phytic Acid and Tannic Acid on Iron Bioavailability from Reconstituted Ferritin Measured by an In Vitro Digestion/Caco-2 Cell Model. British Journal of Nutrition. 101(7):312-316.
HOMOGENIZATION, LYOPHILIZATION OR ACID-EXTRACTION OF MEAT PRODUCTS IMPROVES IRON UPTAKE FROM CEREAL-MEAT PRODUCT COMBINATIONS IN AN IN VITRO DIGESTION/CACO-2 CELL MODEL - (Peer Reviewed Journal)
Pachon, H., Stoltzfus, R., Glahn, R.P. 2009. HOMOGENIZATION, LYOPHILIZATION OR ACID-EXTRACTION OF MEAT PRODUCTS IMPROVES IRON UPTAKE FROM CEREAL-MEAT PRODUCT COMBINATIONS IN AN IN VITRO DIGESTION/CACO-2 CELL MODEL. British Journal of Nutrition. 101(6):816-821.
The bioavailability of iron fortified in whole grain parboiled rice - (Peer Reviewed Journal)
Prom-U-Thai, C., Glahn, R.P., Cheng, Z., Fukai, S., Rerkasem, B., Huang, L. 2009. The bioavailability of iron fortified in whole grain parboiled rice. Food Chemistry. 112(4):982-986.
Effects of Ascorbic Acid, Phytic Acid and Tannic Acid on Ferritin-Iron Bioavailability as Determined Using an In Vitro Digestion/Caco-2 Cell Model - (Peer Reviewed Journal)
Jin, F., Welch, R.M., Glahn, R.P. 2009. Effects of Ascorbic Acid, Phytic Acid and Tannic Acid on Ferritin-Iron Bioavailability as Determined Using an In Vitro Digestion/Caco-2 Cell Model. British Journal of Nutrition. 101(7):972-981.
Characterization of Caco-2 and HT29-MTX co-cultures in an in vitro digestion/cell culture model used to predict iron bioavailability - (Peer Reviewed Journal)
Mahler, G.J., Shuler, M.L., Glahn, R.P. 2008. Characterization of Caco-2 and HT29-MTX co-cultures in an in vitro digestion/cell culture model used to predict iron bioavailability. Journal of Nutritional Biochemistry. 20(7):485-562.
Extrinsic Labeling Method May Not Accurately Measure Fe Absorption from Cooked Pinto Beans (Phaseolus vulgaris):Comparison of Extrinsic and Intrinsic labeling of Beans - (Peer Reviewed Journal)
Jin, F., Glahn, R.P., Rutzke, M., Zhiqiang, C., Welch, R.M. 2008. Extrinsic Labeling Method May Not Accurately Measure Fe Absorption from Cooked Pinto Beans (Phaseolus vulgaris):Comparison of Extrinsic and Intrinsic labeling of Beans. Journal of Agricultural and Food Chemistry. 56(16):6881-6885.
Micronutrient Sprinkles Add More Bioavailable Iron to some Kenyan Complementary Foods: Studies Using an In Vitro Digestion/Caco-2 Cell Culture Model - (Peer Reviewed Journal)
Lung'Aho, M.G., Glahn, R.P. 2009. Micronutrient Sprinkles Add More Bioavailable Iron to some Kenyan Complementary Foods: Studies Using an In Vitro Digestion/Caco-2 Cell Culture Model. Maternal and Child Nutrition. 5 (2):151-158.
Development of a gastrointestinal tract microscale cell culture analog to predict drug transport - (Peer Reviewed Journal)
Mcauliffe, G.J., Chang, J., Glahn, R.P., Shuler, M.L. 2008. Development of a gastrointestinal tract microscale cell culture analog to predict drug transport. Molecular and Cellular Biomechanics. 5(2):119-132.
Iron bioavailability to piglets from red and white common beans (Phaseolus vulgaris L.) - (Peer Reviewed Journal)
Tan, S., Yeung, C., Glahn, R.P., Welch, R.M., Lei, X., Miller, D.D. 2008. Iron bioavailability to piglets from red and white common beans (Phaseolus vulgaris L.). Journal of Agriculture and Food Chemistry. 56(13):5008-14.
Inulin affects iron dialyzability from FeSO4 and FeEDTA solutions but does not alter Fe uptake by Caco-2 cells - (Peer Reviewed Journal)
Laparra, J., Tako, E., Glahn, R.P., Miller, D. 2008. Inulin affects iron dialyzability from FeSO4 and FeEDTA solutions but does not alter Fe uptake by Caco-2 cells. Journal of Agricultural and Food Chemistry. 56:2846-2851.
Supplemental inulin does not enhance iron bioavailability to Caco-2 cells from milk- or soy-based, probiotic-containing, yogurts but incubation at 37 oC does - (Peer Reviewed Journal)
Laparra, J., Tako, E., Glahn, R.P., Miller, D. 2008. Supplemental inulin does not enhance iron bioavailability to Caco-2 cells from milk- or soy-based, probiotic-containing, yogurts but incubation at 37 oC does. Food Chemistry. 109:122-128.
Genetic and biochemical analysis of iron bioavailability in maize - (Abstract Only)
Hoekenga, O., Mwankini, A., Buckler Iv, E.S., Glahn, R.P., Kochian, L.V. 2007. Genetic and biochemical analysis of iron bioavailability in maize. American Society of Agronomy Meetings. Volume 52:102.
Genetic and biochemical analysis of iron bioavailability in maize - (Abstract Only)
Hoekenga, O., Mwaniki, A., Buckler Iv, E.S., Glahn, R.P., Kochian, L.V. 2007. Genetic and biochemical analysis of iron bioavailability in maize (abstract). Agronomy Society of America, Crop Science Society of America, Soil Science Society of America Meeting. Session 176:4
Screening of iron bioavailability patterns in eight bean (Phaseolus vulgaris L.) genotypes using the Caco-2 cell in vitro model - (Peer Reviewed Journal)
Ariza-Nieto, M., Blair, M., Welch, R.M., Glahn, R.P. 2007. Screening of iron bioavailability patterns in eight bean (Phaseolus vulgaris L.) genotypes using the Caco-2 cell in vitro model. Journal of Agricultural and Food Chemistry. 55:7950-7956.
Dietary inulin affects the expression of intestinal enterocyte iron transporters, receptors and storage protein and alters the microbiota in the pig intestine - (Peer Reviewed Journal)
Tako, E., Glahn, R.P., Welch, R.M., Lei, X., Yasuda, K., Miller, D. 2008. Dietary inulin affects the expression of intestinal enterocyte iron transporters, receptors and storage protein and alters the microbiota in the pig intestine. British Journal of Nutrition. 99:472-480.
Iron bioavailability from maize and beans: a comparison of human measurements with Caco-2 cell and algorithm predictions - (Peer Reviewed Journal)
Beisiegel, J.M., Hunt, J.R., Glahn, R.P., Welch, R.M., Menkir, A., Maziya-Dixon, B.B. 2007. Iron bioavailability from maize and beans: a comparison of human measurements with Caco-2 cell and algorithm predictions. American Journal of Clinical Nutrition. 86:388-396.
A COMPARISON OF PHYSICAL PROPERTIES, SCREENING PROCEDURES AND A HUMAN EFFICACY TRIAL FOR PREDICTING THE BIOAVAILABILITY OF COMMERCIAL ELEMENTAL IRON POWDERS USED FOR FOOD FORTIFICATION - (Peer Reviewed Journal)
Lynch, S.R., Bothwell, T., Campbell, L., Cowan, K., Glahn, R.P., Hallberg, L., Hoppe, M., Hulthen, L., Hunt, J.R., Hurrell, R.F., Miller, D., Swain, J., Turner, L., Winichagoon, P., Yeung, C.K., Zeder, C., Zimmermann, M.B. 2007. A comparison of physical properties, screening procedures and a human efficacy trial for predicting the bioavailability of commercial elemental iron powders used for food fortification. International Journal for Vitamin and Nutrition Research. 77:107-124.
Kaempferol in red and pinto bean seed (PHASEOLUS VULGARIS L.) coats inhibits iron bioavailability using an in vitro digestion/human CACO-2 cell model - (Peer Reviewed Journal)
Hu, Y., Cheng, Z., Heller, L., Krasnoff, S.B., Glahn, R.P., Welch, R.M. 2006. Kaempferol in red and pinto bean seed (PHASEOLUS VULGARIS L.) coats inhibits iron bioavailability using an in vitro digestion/human CACO-2 cell model. Journal of Agricultural and Food Chemistry. 54:9254-9261.
Moving toward a more physiological model: application of mucin to refine the in vitro digestion/Caco-2 cell culture system - (Peer Reviewed Journal)
Jin, F., Welch, R.M., Glahn, R.P. 2006. Moving toward a more physiological model: application of mucin to refine the in vitro digestion/Caco-2 cell culture system. Journal of Agricultural and Food Chemistry. 54:8962-8967.
Iron bioavailability from maize and beans: a comparison of human and Caco-2 cell measurements - (Abstract Only)
Beisiegel, J.M., Hunt, J.R., Glahn, R.P., Welch, R.M., Menkir, A., Maziya-Dixon, B.B. 2007. Iron bioavailability from maize and beans: a comparison of human and Caco-2 cell measurements [abstract]. Program Abstracts, Consequences and Control of Micronutrient Deficiencies: Science, Policy, and Programs - Defining the Issues. April 16-18, 2007. Istanbul, Turkey. p. 103.
BREAD BAKING DOES NOT ALTER THE BIOAVAILABILITY OF HYDROGEN-REDUCED IRON POWDER ADDED TO REFINED WHEAT FLOUR - (Peer Reviewed Journal)
Maekawa, A.A., Glahn, R.P., Lei, X., Miller, D. 2006. Bread baking does not alter the bioavailability of hydrogen-reduced iron powder added to refined wheat flour. Journal of Agricultural and Food Chemistry. 54:8362-8368.
IRON DISSOCIATES FROM THE NAFEEDTA COMPLEX PRIOR TO OR DURING INTESTINAL ABSORPTION IN RATS - (Peer Reviewed Journal)
Zhu, L., Yeung, C., Glahn, R.P., Miller, D. 2006. Iron dissociates from the nafeedta complex prior to or during intestinal absorption in rats. Journal of Agricultural and Food Chemistry. 54:7929-7934.
IRON UPTAKE BY CACO-2 CELLS FROM NAFEEDTA AND FESO4: EFFECTS OF ASCORBIC ACID, PH, AND A FE(II) CHELATING AGENT - (Review Article)
Zhu, L., Yeung, C., Miller, D., Glahn, R.P. 2006. Iron uptake by caco-2 cells from nafeedta and feso4: effects of ascorbic acid, ph, and a fe(ii) chelating agent. Journal of Agricultural and Food Chemistry. 54:7924-7928.
IRON (FE) BIOAVAILABILITY AND THE DISTRIBUTION OF ANTI-FE NUTRITION BIOCHEMICALS IN THE UNPOLISHED, POLISHED GRAIN AND BRAN FRACTION OF FIVE RICE GENOTYPES - (Peer Reviewed Journal)
Prom-U-Thai, C., Glahn, R.P., Welch, R.M., Huang, L., Rerkasem, B. 2006. Iron (fe) bioavailability and the distribution of anti-fe nutrition biochemicals in the unpolished, polished grain and bran fraction of five rice genotypes. Journal of the Science of Food and Agriculture. 86(8):1209-1215.
A CACO-2 CELL MODEL PREDICTS RELATIVE IRON ABSORPTION FROM TROPICAL MAIZE BY WOMEN - (Abstract Only)
Beisiegel, J.M., Glahn, R.P., Welch, R.M., Menkir, A., Maziya-Dixon, B.B., Hunt, J.R. 2006. A caco-2 cell model predicts relative iron absorption from tropical maize by women [abstract]. FASEB J. 20(4):A624.
MEAT AND ASCORBIC ACID CAN PROMOTE FE AVAILABILITY FROM FE-PHYTATE BUT NOT FROM FE-TANNIC ACID COMPLEXES - (Peer Reviewed Journal)
Engle-Stone, R., Yeung, A., Welch, R.M., Glahn, R.P. 2005. Meat and ascorbic acid can promote fe availability from fe-phytate but not from fe-tannic acid complexes. Journal of Agricultural and Food Chemistry. 53:10276-10284.
ENDOSPERM SPECIFIC CO-EXPRESSION OF RECOMBINANT SOYBEAN FERRITIN AND ASPERGILLUS PHYTASE IN MAIZE RESULTS IN SIGNIFICANT INCREASES IN THE LEVELS OF BIOAVAILABLE IRON - (Peer Reviewed Journal)
Drakakaki, G., Marcel, S., Glahn, R.P., Lund, L., Periagh, S., Christou, P., Stoger, E. 2005. Endosperm specific co-expression of recombinant soybean ferritin and aspergillus phytase in maize results in significant increases in the levels of bioavailable iron. Plant Molecular Biology. 59(6):869-880.
THE USEFULNESS OF INVITRO MODELS TO PREDICT THE BIOAVAILABILITY OF IRON AND ZINC: A CONSENSUS STATEMENT FROM THE HARVESTPLUS EXPERT CONSULTATION - (Other)
Fairweather-Tait, S., Lynch, Sean, Hunt, J.R., et al. 2005. The usefulness of in vitro models to predict the bioavailability of iron and zinc: a consensus statement from the HarvestPlus expert consultation. International Journal for Vitamin and Nutrition Research.75(6):371-374.
PREBIOTICS AND IRON BIOAVAILABILITY - IS THERE A CONNECTION?– - (Literature Review)
Yeung, C., Miller, D., Welch, R.M., Glahn, R.P. 2005. Prebiotics and iron bioavailability - is there a connection?–. Journal of Food Science. 70:1288-1292.
BIOAVAILABILITY OF ELEMENTAL IRON POWDERS IN BREAD ASSESSED WITH AN IN VITRO DIGESTION/CACO-2 CELL CULTURE MODEL - (Peer Reviewed Journal)
Yeung, C., Miller, D.D., Zhiqiang, C., Glahn, R.P. 2005. Bioavailability of elemental iron powders in bread assessed with an in vitro digestion/caco-2 cell culture model. Journal of Food Science. 70:5199-5203.
GENOTYPE-ENVIRONMENT INTERACTIONS AND STABILITY ANALYSES OF KERNEL-IRON AND -ZINC CONCENTRATIONS IN TROPICAL MAIZE - (Peer Reviewed Journal)
INHIBITION OF IRON UPTAKE FROM IRON SALTS AND CHELATES BY DIVALENT METAL CATIONS IN INTESTINAL EPITHELIAL CELLS - (Peer Reviewed Journal)
Yeung, C.K., Glahn, R.P., Miller, D. 2004. Inhibition of iron uptake from iron salts and chelates by divalent metal cations in intestinal epithelial cells. Journal of Agricultural and Food Chemistry. Available: http://pubs.acs.org/journals/jafcau/.
IRON AVAILABILITY OF A FORTIFIED PROCESSED WHEAT CEREAL: A COMPARISON OF 14 FE FORMS USING AN IN VITRO DIGESTION/CACO-2 MODEL - (Peer Reviewed Journal)
Wortley, G., Leusner, S., Good, C., Gugger, E., Glahn, R.P. 2004. Iron availability of a fortified processed wheat cereal: a comparison of 14 fe forms using an in vitro digestion/caco-2 model. British Journal of Nutrition. 93:65-71.
ENHANCING THE ABSORPTION OF FORTIFICATION IRON: A SUSTAIN TASK FORCE REPORT - (Other)
Yeung, C., Miller, D., Hurrell, R.F., Lynch, S., Bothwell, T., Cori, H., Hertrampf, E., Kratky, Z., Rodenstein, M., Glahn, R.P. 2004. Enhancing the absorption of fortification iron: a sustain task force report. International Journal for Vitamin and Nutrition Research. 74:387-401.
THE EFFECT OF CALCIUM SALTS, ASCORBIC ACID AND PEPTIC PH ON CALCIUM, ZINC AND IRON BIOAVAILABILITIES FROM FORTIFIED HUMAN MILK - (Peer Reviewed Journal)
Etcheverry, P., Wallingford, J., Miller, D., Glahn, R.P. 2005. The effect of calcium salts, ascorbic acid and peptic ph on calcium, zinc and iron bioavailabilities from fortified human milk. International Journal for Vitamin and Nutrition Research. 75:171-178.
IN VITRO DIGESTION/CACO-2 CELL MODEL FOR IRON BIOAVAILABILITY SHOWS STRONG CORRELLATION WITH HUMAN TRIALS - (Peer Reviewed Journal)
Yun, S., Habicht, J., Miller, D.D., Glahn, R.P. 2004. In vitro digestion/caco-2 cell model for iron bioavailability shows strong correllation with human trials. Journal of Nutrition. 134:2717-2721.
IRON ABSORPTION FROM NAFEEDTA IS DOWN-REGULATED IN IRON-LOADED RATS - (Peer Reviewed Journal)
Yeung, C.K., Zhu, L., Glahn, R.P., Miller, D. 2004. Iron absorption from nafeedta is down-regulated in iron-loaded rats. Journal of Nutrition. 134:2270-2274.
CALCIUM, ZINC AND IRON BIOAVAILABILITIES FROM A COMMERCIAL HUMAN MILK FORTIFIER: A COMPARISON STUDY - (Peer Reviewed Journal)
Etcheverry, P., Wallingford, J.C., Miller, D.D., Glahn, R.P. 2004. Calcium, zinc and iron bioavailabilities from a commercial human milk fortifier: a comparison study. Journal of Dairy Science. 87:3629-3637.
CACO-2 CELL FE UPTAKE FROM HUMAN MILK AND INFANT FORMULA - (Peer Reviewed Journal)
Etcheverry, P., Wissler, J., Wortley, G., Glahn, R.P. 2004. Caco-2 cell fe uptake from human milk and infant formula. Nutrition Research. 24(7):573-579.
CARBOHYDRATE FRACTIONS FROM COOKED FISH PROMOTE IRON UPTAKE BY CACO-2 CELLS - (Peer Reviewed Journal)
Glahn, R.P., Huh, E., Hotchkiss, A.T., Brouillette, J.N. 2004. Carbohydrate fractions from cooked fish promote iron uptake by caco-2 cells. Journal of Nutrition. 134:1681-1689.
ASSESSMENT OF CAROTENOID BIOAVAILABILITY OF WHOLE FOODS USING A CACO-2 CELL CULTURE MODEL COUPLED WITH AN IN VITRO DIGESTION - (Peer Reviewed Journal)
Liu, C., Glahn, R.P., Liu, R.H. 2004. Assessment of carotenoid bioavailability of whole foods using a caco-2 cell culture model coupled with an in vitro digestion. Journal of Agricultural and Food Chemistry. 52:4330-4337.
ASSESSMENT OF IRON BIOAVAILABILITY FROM 20 ELITE LATE-MATURING TROPICAL MAIZE VARIETIES USING AN IN VITRO DIGESTION/CACO-2 CELL MODEL - (Peer Reviewed Journal)
Oikeh, S.O., Menkir, A., Maziya-Dixon, B., Welch, R.M., Glahn, R.P. 2004. Assessment of iron bioavailability from 20 elite late-maturing tropical maize varieties using an in vitro digestion/caco-2 cell model. Journal of the Science of Food and Agriculture. 84:1202-1206.
A LOW MOLECULAR WEIGHT FACTOR IN HUMAN MILK WHEY PROMOTES IRON UPTAKE BY CACO-2 CELLS - (Peer Reviewed Journal)
Etcheverry, P., Miller, D.D., Glahn, R.P. 2004. A low molecular weight factor in human milk whey promotes iron uptake by caco-2 cells. Journal of Nutrition. 134(1):93-98.
IRON "BIOFORTIFICATION" OF TROPICAL MAIZE TO REDUCE HUMAN IRON DEFFICIENCY IN WEST AFRICA - (Peer Reviewed Journal)
OIKEH, S.O., MENKIR, A., MAZIYA-DIXON, B., WELCH, R.M., GLAHN, R.P. 2003. IRON "BIOFORTIFICATION" OF TROPICAL MAIZE TO REDUCE HUMAN IRON DEFFICIENCY IN WEST AFRICA. JOURNAL OF PLANT NUTRITION. 26:2307-2319.
ASSESSMENT OF CONCENTRATIONS OF TRACE MINERALS AND BIOAVAILABLE IRON IN GRAINS OF EARLY-MATURING TROPICAL MAIZE VARIETIES - (Peer Reviewed Journal)
OIKEH, S.O., MENKIR, A., MAZIYA-DIXON, B., WELCH, R.M., GLAHN, R.P. ASSESSMENT OF CONCENTRATIONS OF TRACE MINERALS AND BIOAVAILABLE IRON IN GRAINS OF EARLY-MATURING TROPICAL MAIZE VARIETIES. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 2003. v. 51. p. 3688-3694.
IRON BIOAVAILABILITY FROM COMMON RAISIN-CONTAINING FOODS ASSESSED WITH AN IN VITRO DIGESTION/CACO-2 CELL CULTURE MODEL: EFFECTS OF RAISINS - (Peer Reviewed Journal)
Yeung, C.K., Glahn, R.P., Miller, D.D. 2003. Iron bioavailability from common raisin-containing foods assessed with an in vitro digestion/caco-2 cell culture model: effects of raisins. Journal of Food Science. 68(5):1866-1870.
SIMULTANEOUS DETERMINATION OF 45CALCIUM AND 65ZINC UPTAKE BY CACO-2 CELLS - (Peer Reviewed Journal)
Etcheverry, P., Wallingford, J.C., Miller, D.D., Glahn, R.P. 2002. Simultaneous determination of 45calcium and 65zinc uptake by caco-2 cells. Journal of Agricultural and Food Chemistry. 50:6287-6294.
RED GRAPE JUICE INHIBITS IRON BIOAVAILABILITY: APPLICATION OF AN IN VITRO DIGESTION/CACO-2 CELL MODEL - (Peer Reviewed Journal)
BOATO, F., WORTLEY, G.M., LIU, R., GLAHN, R.P. RED GRAPE JUICE INHIBITS IRON BIOAVAILABILITY: APPLICATION OF AN IN VITRO DIGESTION/CACO-2 CELL MODEL. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 2002.
IN VITRO IRON BIOAVAILABILITY AND ANTIOXIDANT ACTIVITY OF RAISINS - (Peer Reviewed Journal)
Yeung, C.K., Glahn, R.P., Wu, X., Liu, R.H., Miller, D.D. 2003. In vitro iron bioavailability and antioxidant activity of raisins. Journal of Food Science. 68(2):701-705.
EFFECTS OF IRON SOURCE ON IRON AVAILABILITY FROM CASEIN AND CASEIN PHOSPHOPEPTIDES - (Peer Reviewed Journal)
A COMPARISON OF IRON BIOAVAILABILITY FROM 15 RICE GENOTYPES: STUDIES USINGAN IN VITRO DIGESTION/CACO-2 CELL CULTURE MODEL - (Peer Reviewed Journal)
INHIBITION OF IRON UPTAKE BY PHYTIC ACID, TANNIC ACID AND ZNCL2: STUDIES USING AN IN VITRO DIGESTION/CACO-2 CELL MODEL - (Peer Reviewed Journal)
COMPARISON OF THE AVAILABILITY OF VARIOUS IRON FORTIFICANTS IN BREAD AND MILK USING AN IN VITRO DIGESTION/CACO-2 CELL CULTURE METHOD - (Peer Reviewed Journal)
DEPHOSPHORYLATION OF SODIUM CASEINATE, ENZYMATICALLY HYDROLYZED CASEIN AND CASEIN PHOSPHOPEPTIDES BY INTESTINAL ALKALINE PHOSPHATASE; IMPLICATIONS FORIRON AVAILABILITY - (Peer Reviewed Journal)
A COMPARISON OF IRON AVAILABILITY FROM COMMERCIAL IRON PREPARATIONS USING AN IN VITRO DIGESTION/CACO-2 CELL CULTURE MODEL - (Peer Reviewed Journal)
SPINACH: NITRATE ANALYSIS OF AN ADVANCED LIFE SUPPORT (ALS) CROP CULTURED UNDER ALS CANDIDATE ARTIFICIAL LIGHT SOURCES - (Proceedings)
APPLICATION OF AN IN VITRO DIGESTION/CACO-2 CELL CULTURE MODEL TO DETERMINE OPTIMAL ASCORBIC ACID TO FE RATIO IN COMMERCIAL INFANT RICE CEREAL - (Peer Reviewed Journal)
CACO-2 CELL FERRITIN FORMATION PREDICTS NON-RADIOLABELED FOOD IRON AVAILABILITY IN AN IN VITRO DIGESTION/CACO-2 CELL CULTURE MODEL - (Peer Reviewed Journal)
DECREASED CITRATE IMPROVES IRON AVAILABILITY FROM INFANT FORMULA: APPLICATION OF AN IN VITRO DIGESTION/CACO-2 CELL CULTURE MODEL - (Peer Reviewed Journal)
IRON UPTAKE IS ENHANCED IN CACO-2 CELL MONOLAYERS BY CYSTEINE AND CYSTEINYL-GLYCINE - (Peer Reviewed Journal)
CACO-2 CELL FERROUS IRON UPTAKE BUT NOT TRANSFER IS DOWN-REGULATED IN CELLS GROWN IN HIGH IRON SERUM-FREE MEDIUM - (Peer Reviewed Journal)
CACO-2 CELL IRON UPTAKE FROM MEAT AND CASEIN DIGESTS PARALLELS IN VIVO STUDIES: USE OF A NOVEL IN VITRO METHOD FOR RAPID ESTIMATION OF IRON BIOAVAILABILITY - (Peer Reviewed Journal)
BATHOPHENANTHROLENE DISULFONIC ACID AND SODIUM DITHIONITE EFFECTIVELY REMOVES SURFACE BOUND IRON FROM CACO-2 CELL MONOLAYERS - (Peer Reviewed Journal)
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