Kumudini M Meepagala
Natural Products Utilization Research
Research Chemist
Phone: (662) 915-1030
Fax: (662) 915-1035
(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)
Publications
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Bioactive Secondary Metabolites from Curvularia spp.: Natural Alternatives for Pest Management in Agriculture
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Larvicidal actvity of constituents from the main Brazilian propolis types: green, red, and brown against Aedes aegypti
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Ribeiro, V.P., Bastos, J.K., Estep Iii, A.S., Meepagala, K.M. 2024. Larvicidal actvity of constituents from the main Brazilian propolis types: green, red, and brown against Aedes aegypti. ACS Omega. 9:35560-35566. https://doi.org/10.1021/acsomega.4c03132.
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Characterization of the Phytotoxic Potential of Seven Copaifera spp. Essential Oils: Analyzing Active Compounds through Gas Chromatography–Mass Spectrometry Molecular Networking
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Ribeiro, V.P., Bajsa Hirschel, J.N., Bastos, J., Reichley, A.C., Duke, S.O., Meepagala, K.M. 2024. Characterization of the Phytotoxic Potential of Seven Copaifera spp. Essential Oils: Analyzing Active Compounds through Gas Chromatography–Mass Spectrometry Molecular Networking. Journal of Agricultural and Food Chemistry. 72:18528-18536. https://doi.org/10.1021/acs.jafc.4c04586.
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Mining Biosynthetic Gene Clusters of Pseudomonas vancouverensis Utilizing Whole Genome Sequencing
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Tamang, P., Upadhaya, A., Paudel, P., Meepagala, K.M., Cantrell, C.L. 2024. Mining Biosynthetic Gene Clusters of Pseudomonas vancouverensis Utilizing Whole Genome Sequencing. Microorganisms. 12:1-17. https://doi.org/10.3390/microorganisms12030548.
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Pantoea ananatis, a plant growth stimulating bacterium, and its metabolites isolated from Hydrocotyle umbellata (dollarweed)
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Meepagala, K.M., Anderson, C.M., Techen, N., Duke, S.O. 2024. Pantoea ananatis, a plant growth stimulating bacterium, and its metabolites isolated from Hydrocotyle umbellata (dollarweed). Plant Signaling and Behavior. 19:1. https://doi.org/10.1080/15592324.2024.2331894.
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Antifungal and Phytotoxic activities of isolated compounds from Helietta parvifolia stems
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Ribeiro, V., Bajsa Hirschel, J.N., Tamang, P., Meepagala, K.M., Duke, S. 2023. Antifungal and phytotoxic activities of isolated compounds from Helietta parvifolia stems. Molecules. 28(23):7930. https://doi.org/10.3390/molecules28237930.
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Synthesis, Herbicidal Activity, and Structure-Activity Relationships of O-Alkyl Analogues of Khellin and Visnagin
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Cantrell, C.L., Travaini, M., Bajsa Hirschel, J.N., Svendsen, L.D., Reichley, A.C., Sosa, G.M., Kim, S., Tamang, P., Meepagala, K.M., Duke, S.O. 2023. Synthesis, Herbicidal Activity, and Structure-Activity Relationships of O-Alkyl Analogues of Khellin and Visnagin. Journal of Agriculture and Food Chemistry. 71:14593-14603. https://doi.org/10.1021/acs.jafc.3c03254.
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Larvicidal constituents from Poncirus trifoliata root extracts
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Meepagala, K.M., Estep III, A.S. 2023. Larvicidal constituents from Poncirus trifoliata root extracts. Journal of Medical Entomology. https://doi.org/10.1093/jme/tjad086.
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Antifungal activity of Poncirus trifoliata roots against Colletotrichum species
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Meepagala, K.M., Tamang, P. 2023. Antifungal activity of Poncirus trifoliata roots against Colletotrichum species. Agricultural Sciences. https://doi.org/10.4236/as.2023.143022.
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Characterization of toxicological and neurophysiological effects of natural product based chromenes to Fall Armyworm, Spodoptera frugiperda
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Mccomic, S.E., Meepagala, K.M., Swale, D. 2021. Characterization of toxicological and neurophysiological effects of natural product based chromenes to Fall Armyworm, Spodoptera frugiperda. Journal of Economic Entomology. https://doi.org/10.1093/jee/toab172.
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Microbial transformation of some simple isoquinoline and benzyl
isoquinoline alkaloids and molecular docking studies of the
metabolites
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El-Aasr, M., Eliwa, D., Albadry, M.A., Ibrahim, A.S., Kabbash, A., Meepagala, K.M., Khan, I.A., Ross, S.A., Khan, S.I. 2021. Microbial transformation of some simple isoquinoline and benzyl isoquinoline alkaloids and molecular docking studies of the metabolites. Phytochemistry. https://doi.org/10.1016/j.phytochem.2021.112828.
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In silico and in vitro studies of isolated constituents from Callistemon citrinus leaves: Anti-microbial potential and inhibition of iNOS activity
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Abdelmalek, E.M., Zulfiqar, F., Albadry, M.A., Khan, S.I., Meepagala, K.M., Ramadan, M.A., Darwish, F.M., Assaf, M.H., Ross, S.A. 2021. In silico and in vitro studies of isolated constituents from Callistemon citrinus leaves: Anti-microbial potential and inhibition of iNOS activity. Phytochemistry. 185. https://doi.org/10.1016/j.phytochem.2021.112745.
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Furanocoumarin with Phytotoxic Activity from the Leaves of Amyris elemifera (Rutaceae)
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Meepagala, K.M., Bracken, A.K., Fronczek, F.R., Johnson, R.D., Wedge, D.E., Duke, S.O. 2020. A novel furanocoumarin with phytotoxic activity from the leaves of Amyris elemifera (Rutaceae). Journal of Agricultural and Food Chemistry. https://www.doi.org/10.1021/acsomega.0c04778.
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Biotransformation of papaverine and in silico docking studies of the metabolites on human phosphodiesterase 10a
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Eliwa, D., Albadry, M.A., Ibrahim, A.S., Kabbash, A., Meepagala, K.M., Khan, I.A., El-Aasr, M., Ross, S.A. 2020. Biotransformation of papaverine and in silico docking studies of the metabolites on human phosphodiesterase 10a. Phytochemistry. https://doi.org/10.1016/j.phytochem.2020.112598.
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Sesquiterpene-a-amino acid quaternary ammonium hybrids from Stereum complicatum (Steraceae)
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Perera, W.H., Meepagala, K.M., Duke, S.O. 2020. Sesquiterpene-a-amino acid quaternary ammonium hybrids from Stereum complicatum (Steraceae). Biochemical Systematics and Ecology. 93,104176. https://doi.org/10.1016/j.bse.2020.104176.
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Sesquiterpenoids from culture of the fungus Stereum complicatum (Steraceae): Structural diversity, antifungal, and phytotoxic activities
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Perera, W.H., Meepagala, K.M., Wedge, D.E., Duke, S.O. 2020. Sesquiterpenoids from culture of the fungus Stereum complicatum (Steraceae): Structural diversity, antifungal, and phytotoxic activities. Phytochemistry Letters. 37:51-58. https://doi.org/10.1016/j.phytol.2020.03.012.
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A phytotoxic and antifungal metabolite (Pyrichalasin H) from a fungus infecting Brachiaria eruciformis (Signal Grass)
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Meepagala, K.M., Clausen, B., Johnson, R.D., Wedge, D.E., Duke, S.O. 2019. A phytotoxic and antifungal metabolite (Pyrichalasin H) from a fungus infecting Brachiaria eruciformis (Signal Grass). Journal of Agricultural Chemistry and Environment. 8(3):115-128. https://doi.org/10.4236/jacen.2019.83010.
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Bioassay-guided isolation and structure elucidation of fungicidal and herbicidal compounds from Ambrosia salsola (Asteraceae)
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Perera, W.H., Meepagala, K.M., Fronczek, F.R., Cook, D., Wedge, D.E., Duke, S.O. 2019. Bioassay-guided isolation and structure elucidation of fungicidal and herbicidal compounds from Ambrosia salsola (Asteraceae). Molecules. 24:1-12. https://doi.org/10.3390/molecules24050835.
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Antibacterial activity of constituents from Mangosteen (Garcinia mangostana) fruit pericarp against several channel catfish pathogens
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Meepagala, K.M., Schrader, K.K. Antibacterial activity of constituents from Mangosteen Garcinia mangostana fruit pericarp against several channel catfish pathogens. Journal of Aquatic Animal Health. 2018;30:179-184. https://doi.org/10.1002/aah.10021.
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Mosquitocidal activity of a naturally occurring isochroman and synthetic analogs from the plant pathogenic fungus, Diaporthe eres against Aedes aegypti (Diptera: Culicidae)
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Meepagala, K.M., Estep, A.S., Clausen, B.M., Becnel, J.J. 2018. Mosquitocidal activity of a naturally occurring isochroman and synthetic analogs from the plant pathogenic fungus, Diaporthe eres against Aedes aegypti (Diptera: Culicidae). Journal of Medical Entomology. 55(4):969–974. doi:10.1093/jme/tjy016.
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Khellin and visnagin, furanochromones from Ammi visnaga (L.) Lam., as potential bioherbicides
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Travaini, M.L., Sosa, G.M., Ceccarelli, E.A., Walter, H., Cantrell, C.L., Carrillo, N.J., Dayan, F.E., Meepagala, K.M., Duke, S.O. 2016. Khellin and visnagin, furanochromones from Amni visnaga (L.) Lam., as potential bioherbicides. Journal of Agricultural and Food Chemistry. 64:9475-9487.
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Mosquitocidal activity of extracts from Ammi visnaga (Apiaceae) seeds
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Meepagala, K.M., Estep, A.S., Becnel, J.J. 2016. Mosquitocidal activity of extracts from Ammi visnaga (Apiaceae) seeds. Journal of Agricultural Chemistry and Environment. 5:170-178.
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Larvicidal and adulticidal activity chroman and chromene analogues against susceptible and permethrin-resistant mosquito strains
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Meepagala, K.M., Estep, A.S., Becnel, J.J. 2016. Larvicidal and adulticidal activity chroman and chromene analogues against susceptible and permethrin-resistant mosquito strains. Journal of Agricultural and Food Chemistry. 64(24):4914-4920.
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Curvularin and dehydrocurvularin as phytotoxic constituents from curvularia intermedia infecting pandanus amaryllifolius
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Meepagala, K.M., Johnson, R.D., Duke, S.O. 2016. Curvularin and dehydrocurvularin as phytotoxic constituents from curvularia intermedia infecting pandanus amaryllifolius. Journal of Agricultural and Food Chemistry. 5:12-22.
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Phomalactone from a phytopathogenic fungus infecting Zinnia elegans (Asteraceae) leaves
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Meepagala, K.M., Johnson, R.D., Techen, N., Wedge, D.E., Duke, S.O. 2015. Phomalactone from a phytopathogenic fungus infecting Zinnia elegans (Asteraceae) leaves. Journal of Chemical Ecology. 41:602-612.
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Antibacterial activity of acylglucinol derivatives against Flavobacterium columnare
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Meepagala, K.M., Schrader, K. 2014. Antibacterial activity of acylglucinol derivatives against Flavobacterium columnare. Journal of Agricultural Chemistry and Environment. 3:89-95.
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Antibacterial compounds from Rutaceae with activities against Flavobacterium columnare and Streptococcus iniae
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Meepagala, K.M., Schrader, K., Burandt, C. 2013. Antibacterial compounds from Rutaceae with activities against Flavobacterium columnare and Streptococcus iniae. Journal of Agricultural Chemistry and Environment. 2(4):90-100.
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Mosquito repellents based on a natural chromene analogue with longer duration of action than N,N-Diethyl-meta-toluamide (DEET)
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Meepagala, K.M., Bernier, U.R., Burandt, C., Duke, S.O. 2013. Mosquito repellents based on a natural chromene analogue with longer duration of action than N,N-Diethyl-meta-toluamide (DEET). Journal of Agricultural and Food Chemistry. 61:9293-9297.
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Phytochemicals for pest management: current advances and future opportunities
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Duke, S.O., Baerson, S.R., Cantrell, C.L., Wedge, D.E., Meepagala, K.M., Pan, Z., Rimando, A.M., Schrader, K., Tabanca, N., Owens, D.K., Dayan, F.E. 2013. Phytochemicals for pest management: current advances and future opportunities. Recent Advances in Phytochemistry. 43:71-94.
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Natural product based chromenes as a novel class of potential termiticide
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Meepagala, K.M., Osbrink, W.L., Burandt, C., Lax, A.R., Duke, S.O. 2011. Natural product based chromenes as a novel class of potential termiticide. Pest Management Science. 67:1446-1450.
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New Class of Algicidal Compounds and Fungicidal Activities
Derived from a Chromene Amide of Amyris texana
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Meepagala, K.M., Schrader, K., Burandt, C., Wedge, D.E., Duke, S.O. 2010. New class of algicidal compounds and fungicidal activities derived from a chromene amide of Amyris texana. Journal of Agricultural and Food Chemistry 17:(58)9476-9482.
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New class of algicidal compounds and fungicidal activities derived from a chromene amide of Amyris texana
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Meepagala, K.M., Schrader, K., Burandt, C., Wedge, D.E., Duke, S.O. 2010. New class of algicidal compounds and fungicidal activities derived from a chromene amide of Amyris texana. Journal of Agricultural and Food Chemistry. 58:9476-9482.
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Natural toxins for use in pest management
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Duke, S.O., Cantrell, C.L., Meepagala, K.M., Wedge, D.E., Tabanca, N., Schrader, K. 2010. Natural toxins for use in pest management. Toxins. 2:1943-1962.
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Managing Earthworm Castings (Oligochaeta: Lumbricidae) in Turfgrass using a Natural By-Product of Tea Oil (Camellia sp.) Manufacture
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Potter, D.A., Redmond, C.T., Meepagala, K.M., Williams, D.W. April 2010. Managing Earthworm Castings (Oligochaeta: Lumbricidae) in Turfgrass using a Natural By-Product of Tea Oil (Camellia sp.) Manufacture. Pest Management Science. 66(4), pp:439-446.
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Algicide Constituents from Swinglea glutinosa
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Purcaro, R., Schrader, K., Burandt, C., Dellagreca, M., Meepagala, K.M. 2009. Algicide Constituents from Swinglea glutinosa. Journal of Agricultural and Food Chemistry. 57:10632-10635.
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DOD AFPMB and USDA ARS team up to develop new insecticides for mosquito control.
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Hoel, D., Pridgeon, J.W., Bernier, U.R., Chauhan, K., Meepagala, K., Cantrell, C. 2010. Departments of Defense and Agriculture team up to develop new insecticides for mosquito control. Wing Beats. 21(1):29-34.
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The Case Against (-)-Catechin Involvement in Allelopathy in Centaurea stoebe (spotted knapweed)
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Duke, S.O., Dayan, F.E., Bajsa, J.N., Meepagala, K.M., Hufbauer, R.A., Blair, A.C. 2009. The Case Against (-)-Catechin Involvement in Allelopathy in Centaurea stoebe (spotted knapweed). Plant Signaling and Behavior. 4(5):422-424.
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Is (-)-Catechin a "Novel Weapon" of Spotted Knapweed (Centaurea stoebe)?
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Duke, S.O., Blair, A.C., Dayan, F.E., Johnson, R.D., Meepagala, K.M., Cook, D., Bajsa, J.N. 2009. Is (-)-Catechin a "Novel Weapon" of Spotted Knapweed (Centaurea stoebe)? Journal of Chemical Ecology. 35:141-153.
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Natural Products for Pest Management
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Duke, S.O., Rimando, A.M., Schrader, K., Cantrell, C.L., Meepagala, K.M., Wedge, D.E., Tabanca, N., Dayan, F.E. 2008. Natural Products for Pest Management in Selected Topics of Natural Products. R. Ikan, ed., World Sci. Publishing Co., Singapore, pp. 209-251.
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Synthesis and structure-activity relationships of 1-undec-10-enoyl-piperidines as adulticides against the yellow fever mosquito Aedes aegypti (Diptera: Culicidae)
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Structure-Activity Relationships of 33 Piperidines as Adulticides against Aedes aegypti(Diptera: Culicidae)
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Pridgeon, J.W., Meepagala, K.M., Becnel, J.J., Clark, G.G., Pereira, R.M., Linthicum, K. 2007. Structure-Activity Relationships of 33 Piperidines as Adulticides against Aedes aegypti(Diptera: Culicidae). Journal of Medical Entomology. 44(2):263-269.
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ALGICIDAL AND ANTIFUNGAL COMPOUNDS FROM THE ROOTS OF RUTA GRAVEOLENS AND SYNTHESIS OF THEIR ANALOGS
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Meepagala, K.M., Schrader, K., Wedge, D.E., Duke, S.O. 2005. Algicidal and antifungal compounds from the roots of ruta graveolens and synthesis of their analogs. Phytochemistry. 66(22): 2689-2695.
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PLANT DERIVED NATURAL PRODUCTS EXHIBITING ACTIVITY AGAINST FORMOSAN SUBTERRANEAN TERMITES (COPTOTERMES FORMOSANUS)
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Meepagala, K.M., Osbrink, W.L., Sturtz, G., Lax, A.R. 2006. Plant derived natural products exhibiting activity against formosan subterranean termites (coptotermes formosanus). Pest Management Science. 62:565-570.
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MOLLUSCICIDAL ACTIVITY OF VULGARONE B FROM ARTEMISIA DOUGLASIANA (BESSER) AGAINST THE INVASIVE, ALIEN, MOLLUSC PEST, POMACEA CANALICULATA (LAMARCK)
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Joshi, R.C., Meepagala, K.M., Sturtz, G., Cagauan, A.G., Mendoza, C.O., Dayan, F.E., Duke, S.O. 2005. Molluscicidal activity of vulgarone b from artemisia douglasiana (besser) against the invasive, alien, mollusc pest, pomacea canaliculata (lamarck). International Journal of Pest Management. 51(3):175-180.
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PHYTOTOXIC AND ANTIFUNGAL COMPOUNDS FROM TWO APIACEAE SPECIES, LOMATIUM CALIFORNICUM AND LIGUSTICUM HULTENII, RICH SOURCES OF Z-LIGUSTILIDE AND APIOL, RESPECTIVELY.
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Meepagala, K.M., Sturtz, G., Wedge, D.E., Schrader, K., Duke, S.O. 2005. Phytotoxic and antifungal compounds from two apiaceae species, lomatium californicum and ligusticum hultenii, rich sources of z-ligustilide and apiol, respectively.. Journal of Chemical Ecology. 31:1567-1578.
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PHYTOTOXINS FROM THE LEAVES OF RUTA GRAVEOLENS
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Hale, A.L., Meepagala, K.M., Oliva, A., Aliotta, G., Duke, S.O. 2004. Phytotoxins from the leaves of ruta graveolens. Journal of Agricultural and Food Chemistry. 2004. V. 52(11). P. 3345-3349.
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ANTIMUTAGENIC ACTIVITY OF BERRY EXTRACTS
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Smith, S.H., Tate, P.L., Huang, G., Magee, J.B., Meepagala, K.M., Wedge, D.E., Larcom, L.L. 2004. Antimutagenic activity of berry extracts. Journal of Medicinal Food. 7:450-455.
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MOLLUSCICIDAL ACTIVITY OF VULGARONE B AGAINST RAM'S HORN SNAIL
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Meepagala, K.M., Sturtz, G., Mischke, C.C., Wise, D., Duke, S.O. 2004. Molluscicidal activity of vulgarone b against ram's horn snail. Pest Management Science. 60:479-482.
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VULGARONE B, THE ANTIFUNGAL CONSTITUENT IN THE STEAM-DISTILLED FRACTION OF ARTEMISIA DOUGLASIANA
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MEEPAGALA, K.M., KUHAJEK, J.M., STURTZ, G.D., WEDGE, D.E. VULGARONE B, THE ANTIFUNGAL CONSTITUENT IN THE STEAM-DISTILLED FRACTION OF ARTEMISIA DOUGLASIANA. JOURNAL OF CHEMICAL ECOLOGY. 2003. v.29(8). p. 1771-1780.
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NATURAL FUNGICIDES FROM RUTA GRAVEOLENS L. LEAVES, INCLUDING A NEW QUINOLONE ALKALOID
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OLIVA, A., MEEPAGALA, K.M., WEDGE, D.E., HARRIES, M.D., HALE, A.L., ALIOTTA, G., DUKE, S.O. 2003. NATURAL FUNGICIDES FROM RUTA GRAVEOLENS L. LEAVES, INCLUDING A NEW QUINOLONE ALKALOID. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 51(4):890-896.
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ANTIFUNGAL CONSTITUENTS OF ESSENTIAL OIL FRACTION OF ARTEMISIA DRACUNCULUS L. VAR. DRACUNCULUS
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MEEPAGALA, K.M., STURTZ, G., WEDGE, D.E. ANTIFUNGAL CONSTITUENTS OF ESSENTIAL OIL FRACTION OF ARTEMISIA DRACUNCULUS L. VAR. DRACUNCULUS. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 2002. v. 50(24). p. 6989-6992.
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MOLLUSCICIDAL AND ANTIFUNGAL ACTIVITY OF ERIGERON SPECIOSUS STEAM DISTILLATE
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MEEPAGALA, K.M., STURTZ, G., WISE, D., WEDGE, D.E. MOLLUSCICIDAL AND ANTIFUNGAL ACTIVITY OF ERIGERON SPECIOSUS STEAM DISTILLATE. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 2002. v. 58. p. 1043-1047.
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ANTICANCER ACTIVITY OF STRAWBERRY, BLUEBERRY AND RASPBERRY EXTRACTS TO BREAST AND CERVICAL CANCER CELLS
- (Peer Reviewed Journal)
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