Paula Do
Foodborne Toxin Detection and Prevention Research
Biological Science Lab Technician
Phone: (510) 559-6478
Fax: (510) 559-6429
(Employee information on this page comes from the REE Directory. Please contact your front office staff to update the REE Directory.)
Publications
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Streptococcal pyrogenic exotoxin B is a superantigen that induces murinesplenocyte proliferation and secretion of IL-2 and IFN-¿¿ ex vivo
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Rasooly, R., Do, P.M., He, X., Hernlem, B.J. 2024. Streptococcal pyrogenic exotoxin B is a superantigen that induces murinesplenocyte proliferation and secretion of IL-2 and IFN-¿¿ ex vivo. FEMS Microbiology Letters. 371.Article fnae036. https://doi.org/10.1093/femsle/fnae036.
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A sensitive, cell-based assay for measuring low-level biological activity of a-amanitin
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Rasooly, R., Do, P.M., He, X., Hernlem, B.J. 2023. A sensitive, cell-based assay for measuring low-level biological activity of a-amanitin. International Journal of Molecular Sciences. 24(22). Article 16402. https://doi.org/10.3390/ijms242216402.
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T-cell-receptor Vß8 for detection of biologically active streptococcal pyrogenic exotoxin type C
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Rasooly, R., Do, P.M., Hernlem, B.J. 2023. T-cell-receptor Vß8 for detection of biologically active streptococcal pyrogenic exotoxin type C. Journal of Dairy Science. 106(10):672-6730. https://doi.org/10.3168/jds.2023-23286.
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Ex vivo and in vitro methods for detection of bioactive staphylococcal enterotoxins
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Rasooly, R., Do, P.M., Hernlem, B.J. 2022. Ex vivo and in vitro methods for detection of bioactive staphylococcal enterotoxins. In: Ossandon, M.R., Baker, H., Rasooly, A., editors. Biomedical Engineering Technologies. Volume 1. New York, NY: Humana Press. p. 237-255. https://doi.org/10.1007/978-1-0716-1803-5_13.
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Human leukemia T-cell lines as alternative to animal use for detecting biologically active Staphylococcal enterotoxin type B
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Rasooly, R., Do, P.M., He, X., Hernlem, B.J. 2021. Human leukemia T-cell lines as alternative to animal use for detecting biologically active Staphylococcal enterotoxin type B. Toxins. 13(5). Article 300. https://doi.org/10.3390/toxins13050300.
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Quantitative bioluminescence assay for measuring Bacillus cereus nonhemolytic enterotoxin complex
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Rasooly, R., Do, P.M., Hernlem, B.J. 2020. Quantitative bioluminescence assay for measuring Bacillus cereus nonhemolytic enterotoxin complex. PLoS ONE. 15(9): Article e0238153. https://doi.org/10.1371/journal.pone.0238153.
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whISOBAXTM inhibits bacterial pathogenesis and enhances the effect of antibiotics
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Rasooly, R., Choi, H., Do, P.M., Morroni, G., Brescini, L., Cironi, O., Giacometti, A., Apostolidis, E. 2020. whISOBAXTM inhibits bacterial pathogenesis and enhances the effect of antibiotics. Antibiotics. 9(5):264. https://doi.org/10.3390/antibiotics9050264.
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CCD based detector for detection of Abrin toxin activity
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Rasooly, R., Do, P.M., Hernlem, B.J. 2020. CCD based detector for detection of Abrin toxin activity. Toxins. 12(2). https://doi.org/10.3390/toxins12020120.
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Witch hazel significantly improves the efficacy of commercially available teat dips
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Rasooly, R., Molnar, A., Do, P.M., Marroni, G., Brescini, L., Cirioni, O., Giavometti, A., Apostolidis, E. 2020. Witch hazel significantly improves the efficacy of commercially available teat dips. Pathogens. 9(2). Article 92. https://doi.org/10.3390/pathogens9020092.
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In-vitro inhibition of staphylococcal pathogenesis by witch-hazel and green tea extracts
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Rasooly, R., Molnar, A., Choi, H., Do, P.M., Racicot, K., Apostolidis, E. 2019. In-vitro inhibition of staphylococcal pathogenesis by witch-hazel and green tea extracts. Antibiotics. 8(4):244. https://doi.org/10.3390/antibiotics8040244.
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T cell receptor Vß9 in method to rapidly detect active staphylococcal enterotoxin type A without live animals
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Rasooly, R., Do, P.M., He, X., Hernlem, B.J. 2019. T cell receptor Vß9 in method to rapidly detect active staphylococcal enterotoxin type A without live animals. Toxins. 11:399. https://doi.org/10.3390/toxins11070399.
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Alternative to animal use for detecting biologically active Staphylococcal enterotoxin type A
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Rasooly, R., Do, P.M., He, X., Hernlem, B.J. 2018. Alternative to animal use for detecting biologically active Staphylococcal enterotoxin type A. Toxins. 10(12):540. https://doi.org/10.3390/toxins10120540.
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Sensitive low-cost CCD-based detector for determination of UV-LED water microbial disinfection
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Rasooly, R., Magoz, Z., Luo, J., Do, P.M., Hernlem, B.J. 2018. Sensitive low-cost CCD-based detector for determination of UV-LED water microbial disinfection. Desalination and Water Treatment. 118:120-125. https://doi.org/10.5004/dwt.2018.22667.
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Low cost bioluminescence imaging as an alternative to in vivo bioassays for quantifying biologically active staphylococcal enterotoxin type E
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Rasooly, R., Do, P.M., Hernlem, B.J. 2017. Low cost bioluminescence imaging as an alternative to in vivo bioassays for quantifying biologically active staphylococcal enterotoxin type E. Sensors and Actuators B: Chemical. 259:357-393. https://doi.org/10.1016/j.snb.2017.12.079.
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TCR-Vß8 as alternative to animal testing for quantifying active SEE
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Rasooly, R., Do, P.M., He, X., Hernlem, B.J. 2017. TCR-Vß8 as alternative to animal testing for quantifying active SEE. Journal of Environmental and Analytical Toxicology. 7(6):527. https://doi.org/10.4172/2161-0525.1000527.
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Interleukin 2 secretion by T cells for detection of biologically active Staphylococcal enterotoxin type E
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Rasooly, R., Do, P.M., Hernlem, B.J. 2017. Interleukin 2 secretion by T cells for detection of biologically active Staphylococcal enterotoxin type E. Journal of Food Protection. 80(11):1857-1862. https://doi.org/10.4315/0362-028X.JFP-17-196.
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Butterfly extracts show antibacterial activity
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Rasooly, R., Do, P.M., Balaban, N., Wolferstan, P., Nash, R., Yael, G. 2017. Butterfly extracts show antibacterial activity. Journal of Agricultural and Food Chemistry. 7:467-479. doi:org/10.4236/aim.2017.76036.
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Rapid cell-based assay for detection and quantification of active staphylococcal enterotoxin type D
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Rasooly, R., Do, P.M., Hernlem, B.J. 2017. Rapid cell-based assay for detection and quantification of active staphylococcal enterotoxin type D. Journal of Food Science. doi: 10.1111/1750-3841.13634.
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Sensitive, rapid, quantitative and in vitro method for the detection of biologically active staphylococcal enterotoxin type E
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Rasooly, R., Do, P.M., Hernlem, B.J. 2016. Sensitive, rapid, quantitative and in vitro method for the detection of biologically active staphylococcal enterotoxin type E. Toxins. 8(5):150. doi: 10.3390/toxins8050150.
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Low cost quantitative digital imaging as an alternative to qualitative in vivo bioassays for analysis of active aflatoxin B1
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Rasooly, R., Do, P.M., Hernlem, B.J. 2016. Low cost quantitative digital imaging as an alternative to qualitative in vivo bioassays for analysis of active aflatoxin B1. Journal of Agricultural and Food Chemistry. 80:405-410.
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The olive compound 4-hydroxytyrosol inactivates Staphyloccoccus aureus bacteria and Staphylococcal enterotoxin A (SEA)
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Friedman, M., Rasooly, R., Do, P.M., Henika, P.R. 2011. The olive compound 4-hydroxytyrosol inactivates Staphyloccoccus aureus bacteria and Staphylococcal enterotoxin A (SEA). Journal of Food Science. 76:M558-M558. doi:10.1111/j.1750-3841.2001.02365.x.
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Auto-presentation of Staphylococcal enterotoxin A by mouse CD4+ T cells
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Rasooly, R., Do, P.M., Hernlem, B.J. 2011. Auto-presentation of Staphylococcal enterotoxin A by mouse CD4+ T cells. Open Journal of Immunology. 1(1):8-14. doi:10.4236/oji.2011.11002.
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Clostridium botulinum neurotoxin type B is heat-stable in milk and not inactivated by pasteurization
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Rasooly, R., Do, P.M. 2010. Clostridium botulinum neurotoxin type B is heat-stable in milk and not inactivated by pasteurization. Journal of Agricultural and Food Chemistry. 58:12557-12561.
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Ingested Shiga Toxin 2 (Stx2) Causes Histopathological Changes in Kidney, Spleen and Thymus Tissues and Mortality in Mice
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Rasooly, R., Do, P.M., Griffey, S.M., Vilches-Moure, J.G., Friedman, M. 2010. Ingested Shiga Toxin 2 (Stx2) Causes Histopathological Changes in Kidney, Spleen and Thymus Tissues and Mortality in Mice. Journal of Agricultural and Food Chemistry. (58):9821-9286
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Inhibition of Biological Activity of Staphylococcal Enterotoxin A (SEA) by Apple Juice and Apple Polyphenols
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Rasooly, R., Do, P.M., Friedman, M. 2010. Inhibition of Biological Activity of Staphylococcal Enterotoxin A (SEA) by Apple Juice and Apple Polyphenols. Journal of Agricultural and Food Chemistry. 58:5421-5426.
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Inhibition of Shiga Toxin 2 (Stx2) in Apple Juices and its Resistance to Pasteurization
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Rasooly, R., Do, P.M., Levin, C.E., Friedman, M. 2010. Inhibition of Shiga Toxin 2 (Stx2) in Apple Juices and its Resistance to Pasteurization. Applied and Environmental Microbiology. Vol. 75(5):M296-M301.
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Shiga toxin Stx2 is heat-stable and not inactivated by pasteurization
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Rasooly, R., Do, P.M. 2009. Shiga toxin Stx2 is heat-stable and not inactivated by pasteurization. International Journal of Food Microbiology. 136(2010):290-294
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In vitro cell based assay for activity analysis of staphylococcal enterotoxin A in food
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Rasooly, R., Do, P.M. 2009. In vitro cell based assay for activity analysis of staphylococcal enterotoxin A in food. FEMS Immunology and Medical Microbiology 56(2009): 172-178.
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In vitro peptide cleavage assay for detection of Botulinum Neurotoxin-A activity in food
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Rasooly, R., Do, P.M. 2008. In vitro peptide cleavage assay for detection of Botulinum Neurotoxin-A activity in food. Applied and Environmental Microbiology. 74(14):4309-4313
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Detection of botulinum neurotoxin-A activity in food by peptide cleavage assay
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Rasooly, R., Stanker, L.H., Carter, J.M., Do, P.M., Cheng, L.W., He, X., Brandon, D.L. 2008. In vitro peptide cleavage assay for detection of Botulinum Neurotoxin-A activity in food. International Journal of Food Microbiiology. 126 (2008):135-139
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ARS News Articles
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