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ARS Home » Northeast Area » Beltsville, Maryland (BHNRC) » Beltsville Human Nutrition Research Center » Diet, Genomics and Immunology Laboratory » People & Locations » Celine Chen
Celine Chen
Diet, Genomics and Immunology Laboratory
Molecular Biologist

Phone: (301) 504-9855 ext. 287
Fax: (301) 504-9062

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Publications (Clicking on the reprint icon Reprint Icon will take you to the publication reprint.)
A type 4 resistant potato starch alters the cecal microbiome and gene expression in mice fed a Western diet based on NHANES data Reprint Icon - (Peer Reviewed Journal)
Smith, A.D., Chen, C.T., Cheung, L., Ward, R., Jones, B., Pletsch, E.A., Dawson, H.D. 2024. A type 4 resistant potato starch alters the cecal microbiome and gene expression in mice fed a Western diet based on NHANES data. Nutrients. 15:3141-3157. https://doi.org/10.1039/d3fo04512a.
Raw potato starch alters the microbiome, colon and cecal gene expression, and resistance to citrobacter rodentium infection in mice fed a western diet Reprint Icon - (Peer Reviewed Journal)
Smith, A.D., Chen, C.T., Cheung, L., Dawson, H.D. 2023. Raw potato starch alters the microbiome, colon and cecal gene expression, and resistance to citrobacter rodentium infection in mice fed a western diet. Frontiers in Nutrition. 9:2022. https://doi.org//10.3389/fnut.2022.1057318.
Immunologic and pathologic characterization of a novel swine biomedical research model for eosinophilic esophagitis Reprint Icon - (Peer Reviewed Journal)
Cortesa, L.M., Brodsky, D., Chen, C.T., Pridgen, T., Odle, J., Snyder, D., Cruse, G., Putikova, A., Masuda, M.Y., Doyle, A.D., Wright, B.L., Dawson, H.D., Blikslager, A., Dellon, E.S., Laster, S.M., Kaser, T. 2022. Immunologic and pathologic characterization of a novel swine biomedical research model for eosinophilic esophagitis. Frontiers in Allergy. 3:2022. https://doi.org//10.3389/falgy.2022.1029184.
Soy formula is not estrogenic and does not result in reproductive toxicity in male piglets: Results from a controlled feeding study Reprint Icon - (Peer Reviewed Journal)
Ronis, M., Gomez-Acevedo, H., Shankar, K., Hennings, L., Sharma, N., Blackburn, M.L., Miousee, I., Dawson, H.D., Chen, C.T., Mercer, K.E., Badger, T.M. 2022. Soy formula is not estrogenic and does not result in reproductive toxicity in male piglets: Results from a controlled feeding study. Nutrients. 14(5):1126. https://doi.org/10.3390/nu14051126.
Resistant potato starch alters the cecal microbiome and gene expression in mice fed a Western diet based on NHANES data Reprint Icon - (Peer Reviewed Journal)
Smith, A.D., Chen, C.T., Cheung, L., Ward, R., Hintze, K., Dawson, H.D. 2022. Resistant potato starch alters the cecal microbiome and gene expression in mice fed a Western diet based on NHANES data. Frontiers in Nutrition. 9. Article 782667. https://doi.org/10.3389/fnut.2022.782667.
Fruit and vegetable supplemented diet modulates the pig transcriptome and microbiome after a two-week feeding intervention Reprint Icon - (Peer Reviewed Journal)
Solano-Aguilar, G.I., Lakshman, S., Shao, J.Y., Chen, C.T., Beshah, E., Dawson, H.D., Vinyard, B.T., Schroeder, S.G., Jang, S., Molokin, A., Urban Jr., J.F. 2021. Fruit and vegetable supplemented diet modulates the pig transcriptome and microbiome after a two-week feeding intervention. Nutrients. 13:4350. https://doi.org/10.3390/nu13124350.
Transcriptome profiles of the skeletal muscle of mature cows during feed restriction and realimentation Reprint Icon - (Peer Reviewed Journal)
Cunningham-Hollinger, H.C., Kuehn, L.A., Cammack, K.M., Hales, K.E., Oliver, W.T., Crouse, M.S., Chen, C.T., Freetly, H.C., Lindholm-Perry, A.K. 2021. Transcriptome profiles of the skeletal muscle of mature cows during feed restriction and realimentation. BMC Research Notes. 14. Article 361. https://doi.org/10.1186/s13104-021-05757-8.
Colon transcriptome is modified by dietary pattern/Atorvastatin interaction in the Ossabaw pig Reprint Icon - (Peer Reviewed Journal)
Shumao, Y., Nirupa, M., Lamon-Fava, S., Solano Aguilar, G., Turner, J.R., Walker, M.E., Zhi, C., Lakshman, S., Chen, C.T., Dawson, H.D., Urban Jr, J.F., Lichtenstein, A.H. 2021. Colon transcriptome is modified by dietary pattern/Atorvastatin interaction in the Ossabaw pig. Journal of Nutritional Biochemistry. 90:108577. https://doi.org/10.1016/j.jnutbio.2020.108570.
Formula diet alters ileal metagenome and transcriptome at weaning and during the postweaning period in a porcine model Reprint Icon - (Peer Reviewed Journal)
Elolimy, A., Washam, C., Byrum, S., Chen, C.T., Dawson, H.D., Bowlin, A.K., Randolph, C., Saraf, M.K., Yeruva, L. 2020. Formula diet alters ileal metagenome and transcriptome at weaning and during the postweaning period in a porcine model. mSystems. 5:e00457-20. https://doi.org/10.1128/mSystems.00457-20.
Molecular and metabolomic changes in the proximal colon of pigs infected with Trichuris suis Reprint Icon - (Peer Reviewed Journal)
Dawson, H.D., Chen, C.T., Li, R.W., Bell, N., Shea-Donohue, T., Kringel, H., Beshah, E., Hill, D.E., Urban Jr, J.F. 2020. Molecular and metabolomic changes in the proximal colon of pigs infected with Trichuris suis. Scientific Reports. 10, 12853. https://doi.org/10.1038/s41598-020-69462-5.
Potentiation of IL-4 signaling by retinoic acid in intestinal epithelial cells and macrophages - mechanisms and targets Reprint Icon - (Peer Reviewed Journal)
Chen, C.T., Smith, A.D., Cheung, L., Pham, Q., Urban Jr, J.F., Dawson, H.D. 2020. Potentiation of IL-4 signaling by retinoic acid in intestinal epithelial cells and macrophages - mechanisms and targets. Frontiers in Immunology. 10.3389. https://doi.org/10.3389/fimmu.2020.00605.
The regulatory actions of retinoic acid on M2 polarization of porcine macrophages Reprint Icon - (Peer Reviewed Journal)
Chen, C.T., Perry, T.L., Chitko-Mckown, C.G., Smith, A.D., Cheung, L., Beshah, E., Urban Jr, J.F., Dawson, H.D. 2019. The regulatory actions of retinoic acid on M2 polarization of porcine macrophages. Developmental and Comparative Immunology. 98(9):20-23. https://doi.org/10.1016/j.dci.2019.03.020.
The porcine translational research database: A manually curated, genomics and proteomics-based research resource - (Peer Reviewed Journal)
Dawson, H.D., Chen, C.T., Gaynor, B., Shao, J.Y., Urban Jr, J.F. 2017. The porcine translational research database: A manually curated, genomics and proteomics-based research resource. Biomed Central (BMC) Genomics. doi: 10.1186/s12864-017-4009-7.
Transcriptome analysis reveals persistent effects of neonatal diet on small intestine gene expression profile in a porcine model - (Abstract Only)
Saraf, M.K., Bowlin, A.K., Chen, C.T., Dawson, H.D., Badger, T.M., Yeruva, L. 2017. Transcriptome analysis reveals persistent effects of neonatal diet on small intestine gene expression profile in a porcine model. Journal of Federation of American Societies for Experimental Biology. 31:434.5.
Male testicular development is affected by estrogens but not altered in neonatal piglets receiving soy infant formula - (Abstract Only)
Mercer, K.E., Chen, C.T., Hennings, L., Sharma, N., Dawson, H.D., Yeruva, L., Ronis, M., Badger, T.M. 2017. Male testicular development is affected by estrogens but not altered in neonatal piglets receiving soy infant formula. Federation of American Societies for Experimental Biology Conference. 31:792.5.
An in-depth comparison of the porcine, murine and human inflammasomes; lessons from the porcine genome and transcriptome - (Peer Reviewed Journal)
Dawson, H.D., Smith, A.D., Chen, C.T., Urban Jr, J.F. 2016. An in-depth comparison of the porcine, murine and human inflammasomes; lessons from the porcine genome and transcriptome. Veterinary Microbiology. pii:S0378-1135(16)30137-7. doi: 10.1016/j.vetmic.2016.05.013.
Understanding the host-adapted state of Citrobacter rodentium by transcriptomic analysis - (Peer Reviewed Journal)
Smith, A.D., Yan, X., Chen, C.T., Dawson, H.D., Bhagwat, A.A. 2016. Understanding the host-adapted state of Citrobacter rodentium by transcriptomic analysis. Archives Of Microbiology. 198:353-362.
Structural and Functional Annotation of the Porcine Immunome Reprint Icon - (Peer Reviewed Journal)
Dawson, H.D., Loveland, J., Pascal, G., Gilbert, J., Uenishi, H., Mann, K., Sang, Y., Zhang, J., Carvalho-Silva, D., Hunt, T., Hardy, M., Hu, Z., Zhao, S., Anselmo, A., Sinkai, H., Chen, C.T., Badaoui, B., Berman, D.J., Amid, C., Kay, M., Lloyd, D., Snow, C., Morozumi, T., Cheng, R., Bystrom, M., Bourneuf, E., Kapetanovic, R., Schwartz, J.C., Kataria, R., Astley, M., Fritz, E., Steward, C., Thomas, M., Wilming, L., Giuffra, E., Archibald, A., Bed'Hom, B., Beraldi, D., Ait-Ali, T., Blecha, F., Botti, S., Freeman, T., Hume, D.A., Lunney, J.K., Murtaugh, M.P., Reecy, J.M., Harrow, J., Rogel-Gaillard, C., Tuggle, C.K. 2013. Structural and Functional Annotation of the Porcine Immunome. Biomed Central (BMC) Genomics. 14:332-370.
Laser capture microdissection coupled with RNA-seq reveals that short cuboidal trophoblast cells of the porcine placenta possess a transcriptome consistent with a migratory cell type - (Abstract Only)
McNeel, A.K., Chen, C.T., Schroeder, S.G., Sonstegard, T.S., Dawson, H.D., Vallet, J.L. 2013. Laser capture microdissection coupled with RNA-seq reveals that short cuboidal trophoblast cells of the porcine placenta possess a transcriptome consistent with a migratory cell type [abstract]. Biology of Reproduction Supplement (46th Annual Meeting of the Society for the Study of Reproduction). pp. 239-240 (Abstract #516).
Application of RNA-seq transcriptomic analysis to reproductive physiology of the pig: Insights into differential trophoblast function within the late gestation porcine placenta - (Review Article)
McNeel, A.K., Chen, C.T., Schroeder, S.G., Sonstegard, T.S., Dawson, H.D., Vallet, J.L. 2013. Application of RNA-seq transcriptomic analysis to reproductive physiology of the pig: Insights into differential trophoblast function within the late gestation porcine placenta. In: Rodriquez-Martinez, H., Soede, N.M., Flowers, W.L., editors. Control of Pig Reproduction IX. Leicestershire, UK: Context Products Ltd. pp. 175-183.
Analysis of pig genomes provide insight into porcine demography and evolution - (Peer Reviewed Journal)
Groenen, M.A., Archibald, A.L., Uenishi, H., Tuggle, C., Takeuchi, Y., Rothschild, M.F., Rogel-Gaillard, C., Park, C., Milan, D., Hendrik-Jan, M., Li, S., Larkin, D., Kim, H., Franz, L.A., Caccamo, M., Hyeonju, A., Aken, B.L., Anselmo, A., Anthon, C., Auvil, L., Bouabid, B., Beattie, C.W., Bendixen, C., Berman, D.J., Blecha, F., Blomberg, J., Bolund, L., Bosse, M., Botti, S., Zhan, B., Bystrom, M., Capitanu, B., Silva, D.C., Chardon, P., Chen, C.T., Cheng, R., Choi, S., Chow, W., Clark, R.C., Clee, C., Crooijmans, R.P., Dawson, H.D., Dehais, P., De Sapio, F., Dibbits, B., Drou, N., Du, Z., Eversole, K., Fadista, J., Fairley, S., Faraut, T., Faulkner, G.J., Fowler, K.E., Fredholm, M., Fritz, E., Gilbert, J.G., Giuffra, E., Gorodkin, J., Griffin, D., Harrow, J.L., Hayward, A., Howe, K., Zhi-Liang, H., Humphray, S.J., Hunt, T., Hornshoj, H., Jeon, J., Jern, P., Jones, M., Jurka, J., Kanamori, H., Kapetanovic, R., Jaebum, K., Kim, J., Kim, K., Kim, T., Larson, G., Lee, K., Lee, K., Leggett, R., Lewin, H.A., Li, Y., Liu, W., Loveland, J.E., Lu, Y., Lunney, J.K., Ma, J., Madsen, O., Mann, K., Mathews, L., Mclaren, S., Morozumi, T., Murtaug, M.P., Narayan, J., Nguyen, D., Ni, P., Oh, S., Onteru, S., Rohrer, G.A., et al. 2012. Analysis of pig genomes provide insight into porcine demography and evolution. Nature. 491(7424):393-8.
Supplemental dietary inulin influences expression of iron and inflammation related genes in young pigs - (Peer Reviewed Journal)
Yasuda, K., Dawson, H.D., Wasmuth, E.V., Roneker, C.A., Chen, C., Urban, J.F., Welch, R.M., Miller, D.D., Lei, X.G. 2009. Supplemental dietary inulin influences expression of iron and inflammation related genes in young pigs. Journal of Nutrition. 139(11):2018-2023.
The Suitability of Swine as Models for Humans to Assess the Effect of Nutrition on Immunity - (Proceedings)
Dawson, H.D., Reece, J.J., Chen, C.T., Urban Jr, J.F. 2008. The suitability of swine as models for humans to assess the effect of nutrition on immunity. International Symposium: Swine And Biomedical Research. p.48.