National Program Leader For:

• Improving Public Health by Understanding Metabolic and Bio-Behavioral Effects of Following Recommendations in the Dietary Guidelines for Americans
  
  Accession Number: 436165
  
  
• Biomarkers of Nutritional Status Resulting from Altered Food Composition
  
  Accession Number: 438154
  
  
• Diet Quality and Physical Activity for Healthy Aging and Chronic Disease Mitigation
  
  Accession Number: 443124
  
  
• Metabolic and Molecular Mechanisms of Healthspan
  
  Accession Number: 443385
  
  
• Impact of Diet on the Aging Brain and Sensory Systems to Improve Healthspan
  
  Accession Number: 443414
  
  
• Defining the Impact of Different Foods or Their Components, in the Context of A Western-Style Diet, on Gut Health
  
  Accession Number: 443596
  
  
• Methods for Healthier Lifestyles to Reduce Diet-related Chronic Disease
  
  Accession Number: 444123
  
  
• Peanut Nutrition
  
  Accession Number: 444324
  
  
• Microbiota and Nutritional Health
  
  Accession Number: 444327
  
  
• Preventing the Development of Childhood Obesity
  
  Accession Number: 444330
  
  
• Molecular, Cellular, and Regulatory Aspects of Obesity Development
  
  Accession Number: 444341
  
  
• Metabolic and Epigenetic Regulation of Nutritional Metabolism
  
  Accession Number: 444343
  
  
• Alternative Proteins Research (Climate)
  
  Accession Number: 444378
  
  
• Early Life Factors and Microbiota Impact on Healthy Development
  
  Accession Number: 445369
  
  
• Improved National Dietary Assessment and the Relationship of Dietary Intake to the Environmental Impact of Foods and Beverages
  
  Accession Number: 445700
  
  
• Strategies to Alter Dietary Food Components and Their Effects on Food Choice and Health-Related Outcomes (BRIDGE)
  
  Accession Number: 445750
  
  
• Food Systems Approach to Understanding the Impact of Pulses on Human Health
  
  Accession Number: 445763
  
  
• Rural Aging Study: Longitudinal Analysis of Community Factors, Diet Quality, and Epigenetic Aging
  
  Accession Number: 445997
  
  
• Interplay of Food and Nutrition Insecurity, Measured and Perceived Diet Quality, and Risk Factors for Cardiovascular Disease
  
  Accession Number: 446259
  
  
• Diet and Physical Activity Interventions to Promote Health in Models for Obesity-Related Diseases
  
  Accession Number: 446381
  
  

Publications (Clicking on the reprint icon will take you to the publication reprint.)

A research roadmap about processed foods, food processing, and human health in the context of the US food system: proceedings from an interdisciplinary workshop - (Peer Reviewed Journal)

O'Connor, L.E., Higgins, K.A., Smiljanec, K., Bergia, R., Brown, A., Baer, D.J., Davis, C.D., Ferruzzi, M., Miller, K., Rowe, S., Rueda, J., Andres, A., Cash, S.B., Coupland, J., Crimmins, M., Fiecke, C., Forde, C.G., Fukagawa, N.K., Hall, K., Hamaker, B., Herrick, K.A., Hess, J.M., Heuven, L.A., Juul, F., Malcomson, F.C., Martinez-Steele, E., Mattes, R.D., Messina, M., Mitchell, A., Zhang, F. 2023. A research roadmap about processed foods, food processing, and human health in the context of the US food system: proceedings from an interdisciplinary workshop. Advances in Nutrition. 14 issue 16. https://doi.org/10.1016/j.advnut.2023.09.005.

Eighty Years of Nutritional Sciences, and Counting - (Peer Reviewed Journal)

Taren, D., Akseer, N., Davis, C.D., Miller, J. 2021. Eighty Years of Nutritional Sciences, and Counting. Nutrition Reviews. Volume 80, Issue 1. doi.org/10.1093/nutrit/nuab112.

DIETARY FOLATE AND SELENIUM AFFECT DIMETHYLHYDRAZINE-INDUCED ABERRANT CRYPT FORMATION, GLOBAL DNA METHYLATION AND ONE-CARBON METABOLISM IN RATS - (Peer Reviewed Journal)

Davis, C.D., Uthus, E.O. 2003. Dietary folate and selenium affect dimethylhydrazine-induced aberrant crypt formation, global dna methylation and one-carbon metabolism in rats. Journal of Nutrition. 133:2907-2914.

DIETARY MANGANESE INTAKE AND TYPE OF LIPID DO NOT AFFECT CLINICAL OR NEUROPSYCHOLOGICAL MEASURES IN HEALTHY YOUNG WOMEN - (Peer Reviewed Journal)

Finley, J.W., Penland, J.G., Pettit, R.E., Davis, C.D. 2003. Dietary manganese intake and type of lipid do not affect clinical or neuropsychological measures in healthy young women. 2003. Journal of Nutrition. v.133. p.2849-2856.

DOWN-REGULATION OF PROLIFERATING CELL NUCLEAR ANTIGEN GENE EXPRESSION OCCURS DURING CELL CYCLE ARREST INDUCED BY HUMAN FECAL WATER IN COLONIC HT-29 CELLS - (Peer Reviewed Journal)

Zeng, H., Davis, C.D. 2003. Down-regulation of proliferating cell nuclear antigen gene expression occurs during cell cycle arrest induced by human fecal water in colonic HT-29 cells. Journal of Nutrition. 133:2682-2687.

DEFICIENT DIETARY SELENIUIM (SE) ADVERSELY AFFECTS PUTATIVE RISK FACTORS FOR COLON CANCER SUSCEPTIBILITY IN RATS - (Abstract Only)

LETTER TO EDITOR: SELENIUM AND HOMOCYSTEINE IN HUMANS - (Other)

Davis, C.D., Uthus, E.O. 2003. Does dietary selenium affect plasma homocysteine concentrations in humans? Journal of Nutrition. 133:2392.

DIETARY SELENIUIM (SE) AND FOLATE AFFECT DIMETHYLHYDRAZINE (DMH)-INDUCED ABERRANT CRYPT FORMATION, GLOBAL DNA METHYLATION AND ONE-CARBON METABOLISM IN RATS - (Abstract Only)

Davis, C.D., Uthus, E.O. 2003. Dietary selenium (SE) and folate affect dimethylhydrazine (DMH)-induced aberrant crypt formation, global DNA methylation and one-carbon metabolism in rats [abstract]. The Federation of American Societies for Experimental Biology Journal. 17:A1371.

DIETARY ARSENITE AFFECTS DIMETHYLHYDRAZINE (DMH)-INDUCED ABERRANT CRYPT FORMATION IN COLON AND GLOBAL DNA METHYLATION IN LIVER OF RATS - (Abstract Only)

Uthus, E.O., Davis, C.D. 2003. Dietary arsenite affects dimethylhydrazine (DMH)-induced aberrant crypt formation in colon and global DNA methylation in liver of rats [abstract]. The Federation of American Societies for Experimental Biology Journal. 17:A1152.

EFFECT OF SELENIUM-ENRICHED BROCCOLI DIET ON DIFFERENTIAL GENE EXPRESSION IN MIN MOUSE LIVER - (Abstract Only)

Zeng, H., Davis, C.D., Finley, J.W. 2003. Effect of selenium-enriched broccoli diet on differential gene expression in min mouse liver [abstract]. Journal of Federation of American Societies for Experimental Biology. 17(5):A1159.

LOW DIETARY COPPER INCREASES FECAL FREE RADICAL PRODUCTION AND FECAL WATER ALKALINE PHOSPHATASE ACTIVITY AND CYTOTOXICITY IN HEALTHY MEN - (Peer Reviewed Journal)

Davis, C.D. Low dietary copper increases fecal free radical production and fecal water alkaline phosphatase activity and cytotoxicity in healthy men. J Nutr 133:522-527, 2003.

EFFECT OF DIETARY COPPER (CU) ON RISK FACTORS FOR COLON CANCER IN HEALTHY MEN - (Abstract Only)

Davis, C.D. Effect of dietary copper (Cu) on risk factors for colon cancer in healthy men. 2003. Journal of Nutrition. v.133(5S-1). p.259E.

DIETARY COPPER BUT NOT DIETARY ZINC DECREASES PROTEIN KINASE C ALPHA EXPRESSION AND DIMETHYLHYDRAZINE-INDUCED ABERRANT CRYPT FOCI FORMATION IN THE RAT COLON - (Abstract Only)

Fox, E., Davis, C.D., Johnson, W.T. 2002. Dietary copper but not dietary zinc decreases protein kinase C alpha expression and dimethylhydrazine-induced aberrant crypt foci formation in the rat colon [abstract]. Proceedings of the North Dakota Academy of Science. 56:45.

BIOTRANSFER POSSIBILITIES OF SELENIUM FROM PLANTS USED IN PHYTOREMEDIATION - (Peer Reviewed Journal)

SELENIUM DEFICIENCY IN FISHER-344 RATS DECREASES PLASMA AND TISSUE HOMOCYSTEINE CONCENTRATIONS AND ALTERS PLASMA HOMOCYSTEINE AND CYSTEINE REDOX STATUS - (Peer Reviewed Journal)

Uthus, E.O., Yokoi, K., Davis, C.D. 2002. Selenium deficiency in Fisher-344 rats decreases plasma and tissue homocysteine concentrations and alters plasma homocysteine and cysteine redox status. Journal of Nutrition. 132:1122-1128.

CHEMICAL VERSUS FOOD FORMS OF SELENIUM IN CANCER PREVENTION - (Review Article)

Davis, C.D., Finley J.W. Chemical versus food forms of selenium in cancer prevention. In: Functional Foods and Nutraceuticals in Cancer Prevention. Watson, Ronald R. (ed); Iowa State Press, Iowa, pp. 55-85, 2003.

DIETARY COPPER AFFECTS AZOXYMETHANE-INDUCED INTESTINAL TUMOR FORMATION AND PROTEIN KINASE C ISOZYME PROTEIN AND MRNA EXPRESSION IN COLON OF RATS - (Peer Reviewed Journal)

Davis, C.D., Johnson, W.T. 2002. Dietary copper affects azoxymethane-induced intestinal tumor formation and protein kinase C isozyme protein and MRNA expression in colon of rats. Journal of Nutrition. 132:1018-1025.

LOW DIETARY COPPER (CU) BUT NOT LOW DIETARY ZINC (ZN) AFFECTS PROTEIN KINASE C AND ALPHA (PKC) EXPRESSION IN RAT COLON AND DIMETHYLHYDRAZINE- INDUCED ABERRANT CRYPT FOCI (ACF) FORMATION - (Abstract Only)

Davis, C.D., Johnson, W.T. 2002. Low dietary copper (Cu) but not low dietary zinc (Zn) affects protein kinase C and alpha (PKC) expression in rat colon and dimethylhydrazine-induced aberrant crypt foci (ACF) formation [abstract]. The Federation of American Societies of Experimental Biology Journal. 16:A374-A375.

DIETARY SELENIUM AND AZADEOXYCYTIDINE TREATMENT AFFECT DIMETHYLHYDRAZINE- INDUCED ABERRANT CRYPT FORMATION IN RAT COLON AND DNA METHYLATION IN HT-29 CELLS - (Peer Reviewed Journal)

Davis, C.D., Uthus, E.O. 2002. Dietary selenium and azadeoxycytidine treatment affect dimethylhydrazine-induced aberrant crypt formation in rat colon and DNA methylation in HT-29 cells. Journal of Nutrition. 132:292-297.

SELENIUM-ENRICHED BROCCOLI DECREASES INTESTINAL TUMORIGENESIS IN MULTIPLE INTESTINAL NEOPLASIA (MIN) MICE - (Peer Reviewed Journal)

Davis, C.D., Zeng, H., Finley, J.W. 2002. Selenium-enriched broccoli decreases intestinal tumorigenesis in multiple intestinal neoplasia (Min) mice. Journal of Nutrition. 132:307-309.

MANGANESE ABSORPTION AND RETENTION IN RATS IS AFFECTED BY THE DEGREE OF SATURATION OF DIETARY FAT - (Proceedings)

ANTICARCINOGENIC PROPERTIES OF HIGH SELENIUM FOODS - (Abstract Only)

Hintze, K.J., Davis, C.D., Gregoire, B.R., Finley, J.W. 2001. Anticarcinogenic properties of high selenium foods [abstract]. Presented at the American Oil Seed Society Meeting, Montreal, Canada.

CANCER-PROTECTIVE PROPERTIES OF HIGH-SELENIUM BROCCOLI - (Peer Reviewed Journal)

SELENIUM (SE) FROM HIGH-SELENIUM BROCCOLI IS UTILIZED DIFFERENTLY THAN SELENITE, SELENATE AND SELENOMETHIONINE, BUT IS MORE EFFECTIVE IN INHIBITING COLON CARCINOGENESIS - (Proceedings)

DIETARY COPPER AND DIMETHYLHYDRAZINE (DMH) AFFECT PROTEIN KINASE C (PKC) ISOZYME PROTEIN AND MRNA EXPRESSION AND THE FORMATION OF ABERRANT CRYPTS IN COLON OF RATS - (Peer Reviewed Journal)

Davis, C.D., Johnson, W.T. 2001. Dietary copper and dimethylhydrazine (DMH) affect protein kinase C (PKC) isozyme protein and MRNA expression and the formation of aberrant crypts in colon of rats. Biofactors. 15:11-26.

LETTER-TO-THE-EDITOR - (Abstract Only)

LOW DIETARY ZINC ALTERS INDICES OF COPPER FUNCTION AND STATUS IN POSTMENOPAUSAL WOMEN - (Review Article)

Nielsen, F.H., Milne, D.B., Davis, C.D. 2001. Low dietary zinc alters indices of copper function and status in postmenopausal women. Nutrition. 17(9):701-708.

HIGH-SELENIUM WHEAT PROTECTS AGAINST COLON CANCER IN RATS - (Abstract Only)

Finley, J.W., Davis, C.D., Hintze, K. 2001. High-selenium wheat protects against colon cancer in rats [abstract]. The Federation of American Societies foe Experimental Biology Journal. 15(4):A62.

PROTECTIVE EFFECTS OF SELENIUM-ENRICHED BROCCOLI AGAINST MAMMARY CANCER ANDCOLONIC ABERRANT CRYPT FORMATION - (Abstract Only)

SELENIUM DEPRIVATION DECREASES THE ACTIVITY OF LIVER BETAINE HOMOCYSTEINE METHYLTRANSFERASEIN RATS - (Abstract Only)

Uthus, E.O., Davis, C.D., Yokoi, K. 2001. Selenium deprivation decreases the activity of liver betaine homocysteine methyltransferasein rats [abstract]. The Federation of American Societies for Experimental Biology Journal. 15:A969.

DIETARY SELENIUM AND METHYLATION STATUS AFFECT DIMETHYLHYDRAZINE-INDUCED ABERRANT CRYPT FORMATION IN RAT COLON - (Abstract Only)

Davis, C.D., Uthus, E.O. 2001. Dietary selenium and methylation status affect dimethylhydrazine-induced aberrant crypt formation in rat colon [abstract]. The Federation of American Societies for Experimental Biology Journal. 15:A952.

DIETARY SELENIUM AND ARSENIC AFFECT DNA METHYLATION IN VITRO IN CACO-2 CELLS IN IN VIVO RAT LIVER AND COLON - (Peer Reviewed Journal)

Davis, C.D., Uthus, E.O., Finley, J.W. 2000. Dietary selenium and arsenic affect DNA methylation in vitro in Caco-2 cells in in vivo rat liver and colon. Journal of Nutrition. 130:2903-2909.

INADEQUATE DIETARY COPPER INCREASES TUMORIGENESIS IN THE MIN MOUSE - (Peer Reviewed Journal)

DIET AND CARCINOGENESIS - (Review Article)

SELENIUM STATUS AFFECTS ARSENIC DEPRIVATION IN RATS - (Proceedings)

Uthus, E.O., Gao, J., Finley, J.W., Davis, C.D., Nielsen, F.H. 2000. Selenium status affects arsenic deprivation in rats. Proceedings of the International Symposium on Metal Ions in Biology and Medicine, San Juan, Puerto Rico, May 7-10, 2002. 6:254-256.

SELENIUM FROM HIGH-SELENIUM BROCCOLI IS PROTECTIVE AGAINST COLON CANCER - (Peer Reviewed Journal)

SELENIUM FROM HIGH-SELENIUM BROCCOLI DOES NOT INDUCE GLUTATHIONE PEROXIDASE(GSH-PX) MRNA PRODUCTION AS WELL AS SELENITE, BUT IS MORE EFFECTIVE IN INHIBITING COLON CARCINOGENESIS - (Abstract Only)

SELENIUM FROM HIGH-SELENIUM BROCCOLI IS PROTECTIVE AGAINST COLON CANCER - (Abstract Only)

Finley, J.W., Gregoire, B.R., Davis, C.D., Hintze, K.J. 2000. Selenium from high-selenium broccoli is protective against colon cancer [abstract]. Presented at the Canadian Association of Laboratory Animal Science, Winnipeg, Manitoba, Canada.

SELENIUM (SE) FROM HIGH-SELENIUM BROCCOLI DOES NOT INDUCE GLUTATHIONE PEROXIDASE (GSH-PX) MRNA PRODUCTION AS WELL AS SELENITE, BUT IS MORE EFFECTIVE IN INHIBITING COLON CARCINOGENESIS. - (Abstract Only)

LOW DIETARY ZINC AND COPPER NEGATIVELY AFFECT PLASMA AND URINE INDICATORS OF BONE HEALTH - (Proceedings)

Nielsen, F.H., Davis, C.D., Milne, D.B. 2000. Low dietary zinc and copper negatively affect plasma and urine. Proceedings of North Dakota Academy of Science. v.54. p. 39.

SELENIUM FROM HIGH-SELENIUM BROCCOLI IS PROTECTIVE AGAINST COLON CANCER - (Abstract Only)

Gregoire, B.R., Finley, J.W., Davis, C.D., Hintze, K.J. 2000. Selenium from high-selenium broccoli is protective against colon cancer [abstract]. Presented at the Great Lakes Regional American Chemical Society Symposium, Fargo, ND.

SELENIUM STATUS AFFECTS ARSENIC DEPRIVATION IN RATS - (Abstract Only)

Uthus, E.O., Gao, J., Finley, J.W., Davis, C.D., Nielsen, F.H. 2000. Selenium status affects arsenic deprivation in rats [abstract]. 6th International Symposium on Metal Ions in Biology and Medicine. Scientific Program and Book of Abstracts. p.133.

MODERATELY HIGH DIETARY INTAKES OF MANGANESE DO NOT CAUSE NEUROLOGIC SIGNS OR SYMPTOMS IN HEALTHY ADULT WOMEN - (Abstract Only)

Penland, J.G., Davis, C.D., Finley, J.W., Pettit, R.E. 2000. Moderately high dietary intakes of manganese do not cause neurologic signs or symptoms in healthy adult women [abstract]. Federation of American Societies for Experimental Biology Journal. 14:A262.

DIETARY COPPER AND DIMETHYLHYDRAZINE (DMH) AFFECT PROTEIN KINASE C (PKC) ISOZYME EXPRESSION IN RAT COLON - (Abstract Only)

Davis, C.D., Johnson, W.T. 2000. Dietary copper and dimethylhydrazine (DMH) affect protein kinase C (PKC) isozyme expression in rat colon [abstract]. The Federation of American Societies for Experimental Biology Journal. 14:A169.

INTERACTIVE EFFECTS OF DIETARY FAT TYPE AND MANGANESE CONCENTRATION IN HEALTHY YOUNG WOMEN - (Abstract Only)

Finley, J.W., Davis, C.D., Penland, J.G. 2000. Interactive effects of dietary fat type and manganese concentration in healthy young women [abstract]. Federation of American Societies for Experimental Biology Journal. 14:A297.

SELENIUM DEPRIVATION DECREASES TOTAL PLASMA HOMOCYSTEINE IN RATS FED A TORULA YEAST-BASED DIET - (Abstract Only)

Uthus, E.O., Finley, J.W., Davis, C.D. 2000. Selenium deprivation decreases total plasma homocysteine in rats fed a torula yeast-based diet [abstract]. The Federation of American Societies for Experimental Biology Journal. 14:A536.

CHANGES IN DIETARY ZINC AND COPPER AFFECT ZINC STATUS INDICATORS OF POSTMENOPAUSAL WOMEN, NOTABLY, EXTRACELLULAR SUPEROXIDE DISMUTASE AND AMYLOID PRECURSOR PROTEINS - (Peer Reviewed Journal)

Davis, C.D., Milne, D.B., Nielsen, F.H. 2000. Changes in dietary zinc and copper affect zinc status indicators of postmenopausal women, notably, extracellular superoxide dismutase and amyloid precursor proteins. American Journal of Clinical Nutrition. 71:781-788.

MANGANESE DEFICIENCY AND TOXICITY: ARE HIGH OR LOW DIETARY AMOUNTS OF MANGANESE CAUSE FOR CONCERNS? - (Peer Reviewed Journal)

PROTECTIVE EFFECTS OF DIFFERENT CHEMICAL FORMS OF SE ON FORMATION OF ABERRANT CRYPT FOCI IN THE COLONS OF RATS WITH CHEMICALLY INDUCED CARCINOGENESIS - (Abstract Only)

EFFECT OF DIEARY COPPER, MANGANESE AND IRON ON THE FORMATION OF ABERRANT CRYPTS IN COLON OF RATS ADMINISTERED 3,2'-DIMETHYL-4-AMINOBIPHENYL - (Peer Reviewed Journal)

EFFECTS OF LOW AND MODERATELY HIGH ZINC INTAKES ON ZINC (ZN), COPPER (CU) AND IRON (FE) NUTRITURE - (Abstract Only)

EFFECT OF DIETARY COPPER, MANGANESE AND IRON ON THE FORMATION OF ABERRANT CRYPTS IN COLON OF RATS ADMINISTERED 3,2'-DIMETHYL-4-AMINOBIPHENYL - (Abstract Only)

DIETARY SELENIUM REDUCES 3,2'-DIMETHYL-4-AMINOBIPHENYL-INDUCED ABERRANT CRYPT FORMATION IN THE RAT - (Peer Reviewed Journal)

THE CHEMICAL FORM OF SELENIUM INFLUENCES 3,2'-DIMETHYL-4-AMINOBIPHENYL-DNA ADDUCT FORMATION IN THE COLON OF THE RAT - (Peer Reviewed Journal)

EXTRACELLULAR SUPEROXIDE DISMUTASE ACTIVITY: A PROMISING INDICATOR OF ZINC STATUS IN HUMANS - (Abstract Only)

NUTRITIONAL BIOAVAILABILITY OF SE IN BROCCOLI - (Abstract Only)

THE METABOLISM, DISTRIBUTION AND CANCER-PREVENTION PROPERTIES OF BROCCOLI CONTAINING HIGH CONCENTRATIONS OF SELENIUM - (Abstract Only)

EFFECT OF BILIARY LIGATION ON MANGANESE ACCUMULATION IN RAT BRAIN - (Peer Reviewed Journal)

EFFECT OF BILIARY LIGATION AND DIETARY MANGANESE ON MANGANESE ACCUMULATION IN RAT BRAIN - (Abstract Only)