Research Project: Orbivirus Pathogenesis, Epidemiology, and Control Measures

Location: Arthropod-borne Animal Diseases Research

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Wolbachia wAlbB inhibits bluetongue and epizootic hemorrhagic fever viruses in Culicoides midge cells - (Peer Reviewed Journal)
Matthews, M.L., Covey, H.O., Drolet, B.S., Brelsfoard, C.L. 2022. Wolbachia wAlbB inhibits bluetongue and epizootic hemorrhagic fever viruses in Culicoides midge cells. Medical and Veterinary Entomology. 36(3):320-328. https://doi.org/10.1111/mve.12569.

Species identity, life history, and geographic distance influence gut bacterial communities in lab-reared and European field-collected Culicoides biting midges - (Peer Reviewed Journal)
Mohlmann, T.W., Ter Braak, C.J., Te Beest, D., Hendriks, M., Nijhuis, E.H., Warris, S., Drolet, B.S., Van Overbeek, L., Koenraadt, C.J. 2021. Species identity, life history, and geographic distance influence gut bacterial communities in lab-reared and European field-collected Culicoides biting midges. Microbial Ecology. 84, pages267–284 (2022). https://doi.org/10.1007/s00248-021-01822-8.

Exposure of Culicoides sonorensis to enzootic strains of bluetongue virus demonstrates temperature- and virus-specific effects on virogenesis - (Peer Reviewed Journal)
Kopanke, J., Lee, J., Stenglein, M., Carpenter, M., Cohnstaedt, L.W., Wilson, W.C., Mayo, C. 2021. Exposure of Culicoides sonorensis to enzootic strains of bluetongue virus demonstrates temperature- and virus-specific effects on virogenesis. Viruses. 13(6):1016. https://doi.org/10.3390/v13061016.

A duplex fluorescent microsphere immunoassay for detection of bluetongue and epizootic hemorrhagic disease virus antibodies in cattle sera - (Peer Reviewed Journal)
Drolet, B.S., Reister-Hendricks, L.M. 2021. A duplex fluorescent microsphere immunoassay for detection of bluetongue and epizootic hemorrhagic disease virus antibodies in cattle sera. Viruses. 13(4):682. https://doi.org/10.3390/v13040682.

Vector competence of Florida Culicoides insignis (Diptera: Ceratopogonidae) for epizootic hemorrhagic disease virus serotype 2 - (Peer Reviewed Journal)
McGregor, B.L., Erram, D., Alto, B.W., Lednicky, J., Wisely, S.M., Burkett-Cadena, N.D. 2021. Vector competence of Florida Culicoides insignis (Diptera: Ceratopogonidae) for epizootic hemorrhagic disease virus serotype 2. Viruses. 13(3):410. https://doi.org/10.3390/v13030410.

Research Updates from the Arthropod-Borne Animal Diseases Research Unit - (Proceedings)

Impact of gut bacteria on the infection and transmission of pathogenic arboviruses by biting midges and mosquitoes - (Peer Reviewed Journal)
Mohlmann, T., Vogels, C., Goertz, G., Pijlman, G., Ter Braak, C., Te Beest, D., Hendriks, M., Nijhuis, E., Warris, S., Drolet, B.S., Van Overbeek, L., Koenraadt, C. 2020. Impact of gut bacteria on the infection and transmission of pathogenic arboviruses by biting midges and mosquitoes. Microbial Ecology. 80:703-717. https://doi.org/10.1007/s00248-020-01517-6.

Vector competence is strongly affected by a small deletion or point mutations in bluetongue virus - (Peer Reviewed Journal)
Van Gennip, R., Drolet, B.S., Rozo Lopez, P., Roost, A., Boonstra, J., Van Rijn, P. 2019. Vector competence is strongly affected by a small deletion or point mutations in bluetongue virus. Parasites & Vectors. 12:470. https://doi.org/10.1186/s13071-019-3722-2.

EHDV-2 infection prevalence varies in Culicoides sonorensis after feeding on infected white-tailed deer over the course of Viremia - (Peer Reviewed Journal)
Mendiola, S.Y., Mills, M.K., Maki, E.C., Drolet, B.S., Wilson, W.C., Berghaus, R., Stallknecht, D.E., Breitenbach, J.E., Mcvey, D.S., Ruder, M.G. 2019. EHDV-2 infection prevalence varies in Culicoides sonorensis after feeding on infected white-tailed deer over the course of Viremia. Viruses. 11:371-385. https://doi.org/10.3390/v11040371.

Inter-serotype reassortment among epizootic hemorrhagic disease viruses in the United States - (Peer Reviewed Journal)
Wang, L., Lanka, S., Cassout, D., Mateus-Pinilla, N., Li, G., Wilson, W.C., Yoo, D., Frederickson, R. 2019. Inter-serotype reassortment among epizootic hemorrhagic disease viruses in the United States. Transboundary and Emerging Diseases. https://doi.org/10.1111/tbed.13257.

Bluetongue and Epizootic Hemorrhagic Disease Viruses: Recent developments with these globally re-emerging infections of ruminant animals - (Peer Reviewed Journal)
Maclachlan, N., Zientara, S., Wilson, W.C., Richt, J., Savini, G. 2019. Bluetongue and Epizootic Hemorrhagic Disease Viruses: Recent developments with these globally re-emerging infections of ruminant animals. Popular Publication. 34:56-62. https://doi.org/10.1016/j.coviro.2018.12.005.

Physiological and immunological responses to Culicoides sonorensis blood feeding: A murine model - (Peer Reviewed Journal)
Lehiy, C.J., Reister-Hendricks, L.M., Ruder, M., McVey, D.S., Drolet, B.S. 2018. Physiological and immunological responses to Culicoides sonorensis blood feeding: A murine model. Parasites & Vectors. 11(1):358-370. https://doi.org/10.1186/s13071-018-2935-0.

Vector competence: The role of viral proteins in transmission of bluetongue virus by midges - (Abstract Only)
Van Rijn, P., Drolet, B.S., Roost, A., Bonstra, J., Van Gennip, R. 2018. Vector competence: The role of viral proteins in transmission of bluetongue virus by midges. Meeting Abstract. 1:1.

Immunohistochemical Insights in Vector-Borne Disease Research - (Abstract Only)
Drolet, B.S., Mills, M. 2018. Immunohistochemical Insights in Vector-Borne Disease Research. Meeting Abstract. 04/24/2018; San Diego, CA.

The role of gut bacteria in Schmallenberg virus transmission by Culicoides biting midges - (Abstract Only)
Mahlmann, T., Vogels, C., Drolet, B.S., Hendriks, M., Nijhuis, E., Van Overbeek, L., Ter Braak, C., Warris, S., Koenraadt, C. 2018. The role of gut bacteria in Schmallenberg virus transmission by Culicoides biting midges. Meeting Abstract. 04/05/2018;Lelystand, NL.

Dynamics of epizootic hemorrhagic disease virus serotype 2 infection within the vector, Culicoides sonorensis (Diptera: Ceratopogonidae) - (Peer Reviewed Journal)
Mills, M.K., Ruder, M.G., Nayduch, D., Michel, K., Drolet, B.S. 2017. Dynamics of epizootic hemorrhagic disease virus serotype 2 infection within the vector, Culicoides sonorensis (Diptera: Ceratopogonidae). PLoS One. https://doi.org/10.1371/journal.pone.0188865.

Some recent US Bluetongue virus serotype 3 isolates found outside of Florida indicate evidence of reassortment with endemic co-circulating serotypes - (Peer Reviewed Journal)
Schirtzinger, E.E., Jasperson, D.C., Ostlund, E.N., Johnson, D.J., Wilson, W.C. 2017. Some recent US Bluetongue virus serotype 3 isolates found outside of Florida indicate evidence of reassortment with endemic co-circulating serotypes. Journal of General Virology. https://doi.org/10.1099/jgv.0.000965.

Recent US Bluetongue virus serotype 3 isolates found outside of Florida indicate evidence of reassortment with endemic co-circulating endemic serotypes - (Peer Reviewed Journal)
Schirtzinger, E.E., Jasperson, D.C., Ostlund, E.N., Johnson, D.J., Wilson, W.C. 2018. Some recent US Bluetongue virus serotype 3 isolates found outside of Florida indicate evidence of reassortment with endemic co-circulating serotypes. Virus Genes. 99:157-168.

Role of mammalian immune responses in vector-enhanced orbiviral transmission - (Abstract Only)
Drolet, B.S., Lehiy, C.J., Reister-Hendricks, L.M., Ruder, M.G., McVey, D.S. 2017. Role of mammalian immune responses in vector-enhanced orbiviral transmission. American Society of Tropical Medicine and Hygiene. 1:1.

Disa vaccines for Bluetongue: A novel vaccine approach for insect-borne diseases - (Abstract Only)
Van Rijn, P.A., Boonstra, J., Daus, F.J., Feenstra, F., Van Gennip, R., Maris-Veldhuis, M.A., Tacken, M., Van De Water, S., Potgieter, C., Drolet, B.S. 2017. DISA vaccines for Bluetongue: A Novel Vaccine Approach for Insect-Borne Diseases. Meeting Abstract. 1/1.

Innate Mammalian Immune Response to Culicoides Feeding - (Abstract Only)
Drolet, B.S., Lehiy, C.J., Reister-Hendricks, L.M., Ruder, M.G., Mcvey, D.S. 2017. Innate Mammalian Immune Response to Culicoides Feeding. Meeting Abstract. 1.

Culicoides: The Controller of Orbivirus Transmission - (Abstract Only)
Drolet, B.S., Lehiy, C.J., Reister-Hendricks, L.M., Ruder, M.G., Mcvey, D.S. 2017. Culicoides: The Controller of Orbivirus Transmission. Meeting Abstract. 1.

Non-essential viral proteins of orbiviruses are essential for vector-borne spread by midges - (Abstract Only)
Van Rijn, P.A., Feenstra, F., Potgieter, C., Drolet, B.S., Van De Water, S., Van Gennip, R. 2017. Non-essential viral proteins of orbiviruses are essential for vector-borne spread by midges. Meeting Abstract. 1: 1-1.

Disabled infectious single animal (DISA) vaccine against Bluetongue by deletion of viroporin-like NS3/NS3a expression is effective, safe, and enables differentiation of infected from vaccinated animals (DIVA) - (Abstract Only)
Feenstra, F., Van Gennip, R., Van De Water, S., Drolet, B.S., Maris-Veldhuis, M. 2015. Disabled infectious single animal (DISA) vaccine against Bluetongue by deletion of viroporin-like NS3/NS3a expression is effective, safe, and enables differentiation of infected from vaccinated animals (DIVA). Meeting Abstract. 12: 153.