Research Project: Improving Lifetime Productivity in Swine using Systems Biology and Precision Management Approaches

Location: Livestock Bio-Systems

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Gonadotropin-releasing hormone II and its receptor regulate motility, morphology, and kinematics of porcine spermatozoa in vitro - (Peer Reviewed Journal)
Desaulniers, A.T., Ross, C.E., Cederberg, R.A., Lovercamp, K.W., Lents, C.A., White, B.R. 2024. Gonadotropin-releasing hormone II and its receptor regulate motility, morphology, and kinematics of porcine spermatozoa in vitro. General and Comparative Endocrinology. 361. Article 114653. https://doi.org/10.1016/j.ygcen.2024.114653.

Development of KISS1 knockout pigs is characterized by hypogonadotropic hypogonadism, normal growth, and reduced skatole - (Peer Reviewed Journal)
Ahern, D.F., Martins, K., Florez, J.M., Ross, C.E., Huisman, A., Cushman, R.A., Shuping, S.L., Nestor, C.C., Desaulniers, A.T., White, B.R., Sonstegard, T.S., Lents, C.A. 2024. Development of KISS1 knockout pigs is characterized by hypogonadotropic hypogonadism, normal growth, and reduced skatole. Biology of Reproduction. 111(5):1082-1096. https://doi.org/10.1093/biolre/ioae140.

Isolation and characterization of extracellular vesicles from maternal and embryonic secretions during the initiation of porcine conceptus elongation - (Abstract Only)

Knockdown of gonadotropin-releasing hormone II receptor impairs ovulation rate, corpus luteum development, and progesterone production in gilts - (Peer Reviewed Journal)
Desaulniers, A.T., Cederberg, R.A., Lents, C.A., White, B.R. 2024. Knockdown of gonadotropin-releasing hormone II receptor impairs ovulation rate, corpus luteum development, and progesterone production in gilts. Animals. 14. Article 2350. https://doi.org/10.3390/ani14162350.

Serum concentrations of luteinizing hormone (LH) and follicle stimulating hormone (FSH) in KISS1 knockout gilts treated with neurokinin B, kisspeptin, and GnRH hormone analogs - (Abstract Only)

Putative metabolites for sow lifetime opportunity and production traits - (Abstract Only)
Rempel, L.A., Lee, R. 2024. Putative metabolites for sow lifetime opportunity and production traits. Journal of Animal Science. 102(Supplement 2):329-330. https://doi.org/10.1093/jas/skae102.376.

Clustering of multi-tissue transcriptomes in gilts with normal cyclicity or delayed puberty reveals genes related to pubertal development - (Peer Reviewed Journal)
Wijesena, H.R., Keel, B.N., Nonneman, D.J., Cushman, R.A., Lents, C.A. 2023. Clustering of multi-tissue transcriptomes in gilts with normal cyclicity or delayed puberty reveals genes related to pubertal development. Biology of Reproduction. 110(2):261-274. https://doi.org/10.1093/biolre/ioad145.

Early- and mid-lactation milk traits are associated with piglet growth during lactation - (Peer Reviewed Journal)
Rempel, L.A., Oliver, W.T., Miles, J.R. 2023. Early- and mid-lactation milk traits are associated with piglet growth during lactation. Journal of Animal Science. 101. Article skad340. https://doi.org/10.1093/jas/skad340.

Evaluation of uterine capacity during late gestation in young commercial females over the past twenty years - (Abstract Only)
Miles, J.R., Rempel, L.A. 2023. Evaluation of uterine capacity during late gestation in young commercial females over the past twenty years. Reproduction, Fertility and Development. 36(2).Article 178. https://doi.org/10.1071/RDv36n2Ab54.

Relationships of genomic estimated breeding values for age at puberty, birth weight, and growth during development in normal cyclic and acyclic gilts - (Peer Reviewed Journal)
Wijesena, H.R., Nonneman, D.J., Rohrer, G.A., Lents, C.A. 2023. Relationships of genomic estimated breeding values for age at puberty, birth weight, and growth during development in normal cyclic and acyclic gilts. Journal of Animal Science. 101. Article skad258. https://doi.org/10.1093/jas/skad258.

Characterization of mRNA expression for key glycerophospholipid and sphingolipid enzymes within trophectoderm and embryonic disc during initiation of porcine conceptus elongation - (Abstract Only)
Miles, J.R., Rempel, L.A., Snider, A.P., Pannier, A.K. 2023. Characterization of mRNA expression for key glycerophospholipid and sphingolipid enzymes within trophectoderm and embryonic disc during initiation of porcine conceptus elongation [abstract]. Molecular Reproduction and Development. 90(7):736. https://doi.org/10.1002/mrd.23697.

The kisspeptin knockout pig; a new model for dissecting mechanisms controlling reproduction - (Abstract Only)
Lents, C.A., Florez, J.M., Martins, K., Bostrom, J.R., Rodriquez-Villamil, P., Ongaratto, F., Huisman, A., Larson, S.A., Ahern, D.F., Ross, C.E., Elsken, D.H., Cushman, R.A., White, B.R., Sonstegard, T.S. 2023. The kisspeptin knockout pig; a new model for dissecting mechanisms controlling reproduction. American Society of Animal Science Proceedings. 101(Supplement 3):234-235. https://doi.org/10.1093/jas/skad281.283.

KISS1 knockout boars have decreased concentrations of gonadotropins leading to smaller testes and reduced skatole in backfat - (Abstract Only)
Ahern, D.F., Florez, J.M., Martins, K., Huisman, A., Sonstegard, T.S., White, B.R., Lents, C.A. 2023. KISS1 knockout boars have decreased concentrations of gonadotropins leading to smaller testes and reduced skatole in backfat. American Society of Animal Science Proceedings. 101(Supplement 3):226-227. https://doi.org/10.1093/jas/skad281.275.

Application of bayespulse and pulsar otago to quantify luteinizing hormone pulses in ovariectomized gilts - (Abstract Only)
Lents, C.A., Wilson, K.E., Wijesena, H.R. 2023. Application of bayespulse and pulsar otago to quantify luteinizing hormone pulses in ovariectomized gilts [abstract]. Molecular Reproduction and Development. 90(7):738. https://doi.org/10.1002/mrd.23697.

Secreted metabolome of porcine blastocysts encapsulated within in vitro 3D alginate hydrogel culture systems undergoing morphological changes provides insights into specific mechanisms involved in the initiation of porcine... - (Peer Reviewed Journal)
Walsh, S.C., Miles, J.R., Broeckling, C.D., Rempel, L.A., Wright-Johnson, E.C., Pannier, A.K. 2023. Secreted metabolome of porcine blastocysts encapsulated within in vitro 3D alginate hydrogel culture systems undergoing morphological changes provides insights into specific mechanisms involved in the initiation of porcine conceptus elongation. Journal of Reproduction, Fertility and Development. 35(5):375-394. https://doi.org/10.1071/RD22210.

Diminished reproductive hormone concentrations in GnRHR-II knockdown gilts during the follicular phase of the estrous cycle may be attributed to reduced GnRHR-II levels in theca cells - (Abstract Only)
Ross, C.E., Desaulniers, A.T., Cederberg, R.A., Choat, F.H., Elsken, D.H., Kurz, S.G., Mills, G.A., Lents, C.A., White, B.R. 2023. Diminished reproductive hormone concentrations in GnRHR-II knockdown gilts during the follicular phase of the estrous cycle may be attributed to reduced GnRHR-II levels in theca cells [abstract]. Molecular Reproduction and Development. 90(7):724. https://doi.org/10.1002/mrd.23697.

Multi clustering of the hypothalamic–pituitary–ovary transcriptome in gilts with normal cyclicity or delayed puberty reveals genes related to puberty - (Abstract Only)
Wijesena, H., Keel, B.N., Nonneman, D.J., Rohrer, G.A., Snelling, W.M., Lents, C.A. 2023. Multi clustering of the hypothalamic–pituitary–ovary transcriptome in gilts with normal cyclicity or delayed puberty reveals genes related to puberty [abstract]. In: Proceedings of the Plant and Animal Genome Conference. January 13-18, 2023, San Diego, California. PE0874.