Research Project: The Roles of Forage and Phytochemicals at the Plant-Microbe-Animal Nexus for Sustainable Ruminant

Location: Forage-animal Production Research

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Ergot alkaloid consumption alters serotonin receptor-induced vasoactivity in ovine umbilical vasculature - (Peer Reviewed Journal)

Serotonin receptor-mediated vasorelaxation occurs primarily through 5-HT4 activation in bovine lateral saphenous vein - (Peer Reviewed Journal)
Trotta, R.J., Harmon, D.L., Klotz, J.L. 2024. Serotonin receptor-mediated vasorelaxation occurs primarily through 5-HT4 activation in bovine lateral saphenous vein. Physiological Reports. 12: Article e16128. https://doi.org/10.14814/phy2.16128.

Microbial-derived exerkines prevent skeletal muscle atrophy - (Pre-print Publication)
Valentino, T.R., Burke, B.L., Kang, G., Goh, J., Dungan, C.M., Ismaeel, A., Mobley, B.C., Flythe, M.D., Wen, Y., McCarthy, J.J. 2024. Microbial-derived exerkines prevent skeletal muscle atrophy. bioRxiv. https://doi.org/10.1101/2024.05.29.596432.

5-hydroxytryphophan mitigates ergot alkaloid-induced suppression of serotonin and feed intake in cattle - (Peer Reviewed Journal)
Valente, E.L., Klotz, J.L., Markmann, R.C., Edwards, J.L., Harmon, D.L. 2024. 5-hydroxytryphophan mitigates ergot alkaloid-induced suppression of serotonin and feed intake in cattle. Journal of Animal Science. 102. Article skae083. https://doi.org/10.1093/jas/skae083.

Levodopa attenuates the feed intake reduction caused by ergot alkaloids in cattle - (Peer Reviewed Journal)
Valente, E.L., Klotz, J.L., Markmann, R.C., Trotta, R.J., Edwards, J.L., May, J.B., Harmon, D.L. 2024. Levodopa attenuates the feed intake reduction caused by ergot alkaloids in cattle. Journal of Animal Science. 102. Article skae078. https://doi.org/10.1093/jas/skae078.

Use of agomir and antagomir technologies to alter satellite cell proliferation in vitro, mirna expression and muscle fiber hypertrophy in intrauterine growth restricted lambs - (Peer Reviewed Journal)
Greene, M.A., Worley, G.A., Udoka, A., Powell, R.R., Bruce, T., Klotz, J.L., Bridges, Jr., W.C., Duckett, S.K. 2023. Use of agomir and antagomir technologies to alter satellite cell proliferation in vitro, mirna expression and muscle fiber hypertrophy in intrauterine growth restricted lambs. Frontiers in Molecular Biosciences. 10. Article 1286890. https://doi.org/10.3389/fmolb.2023.1286890.

Postruminal casein infusion and exogenous glucagon-like peptide 2 administration differentially stimulate pancreatic a-amylase and small intestinal a-glucosidase activity in cattle - (Peer Reviewed Journal)
Trotta, R.J., Swanson, K.C., Klotz, J.L., Harmon, D.L. 2023. Postruminal casein infusion and exogenous glucagon-like peptide 2 administration differentially stimulate pancreatic a-amylase and small intestinal a-glucosidase activity in cattle. Journal of Nutrition. https://doi.org/10.1016/j.tjnut.2023.08.009.

Editorial: Natural products in animal feed and production systems - (Review Article)
Klotz, J.L., MacAdam, J.W., Flythe, M.D. 2023. Editorial: Natural products in animal feed and production systems. Frontiers in Animal Science. 4. Article 1204663. https://doi.org/10.3389/fanim.2023.1204663.

Impact of ergot alkaloid and steroidal implant on whole-body protein turnover and expression of mTOR pathway proteins in muscle of cattle - (Peer Reviewed Journal)
Ferguson, T.D., Loos, C.M., Vanzant, E.S., Urschel, K.L., Klotz, J.L., McLeod, K.M. 2023. Impact of ergot alkaloid and steroidal implant on whole-body protein turnover and expression of mTOR pathway proteins in muscle of cattle. Frontiers in Veterinary Science. 10. Article 1104361. https://doi.org/10.3389/fvets.2023.1104361.

Duration of ergovaline exposure influences serotonin-mediated vasoactivity of bovine mesenteric vasculature - (Peer Reviewed Journal)
Trotta, R.J., Harmon, D.L., Ji, H., Klotz, J.L. 2023. Duration of ergovaline exposure influences serotonin-mediated vasoactivity of bovine mesenteric vasculature. Journal of Animal Science. 100. https://doi.org/10.1093/jas/skad100.

Reduction in rumen tetracycline-insensitive bacteria during a grain challenge using the isoflavone biochanin A - (Peer Reviewed Journal)
Flythe, M.D., Davis, B.E., Kagan, I. 2023. Reduction in rumen tetracycline-insensitive bacteria during a grain challenge using the isoflavone biochanin A. Veterinary Sciences. 10(4). Article 273. https://doi.org/10.3390/vetsci10040273.

Physiological impact of ergot alkaloid consumption in ruminant livestock - (Proceedings)

Red clover supplementation modifies rumen fermentation and promotes feed efficiency in ram lambs - (Peer Reviewed Journal)
Weinert-Nelson, J.R., Ely, D.G., Flythe, M.D., Hamilton, T.A., May, J.B., Ferrell, J.L., Hamilton, M.C., Jacks, W.L., Davis, B.E. 2023. Red clover supplementation modifies rumen fermentation and promotes feed efficiency in ram lambs. Journal of Animal Science. 101. Article skad036. https://doi.org/10.1093/jas/skad036.

Influence of intra-abomasal administration of L-DOPA on circulating catecholamines and feed intake in cattle - (Peer Reviewed Journal)
Valente, E.E., Klotz, J.L., Egert-McLean, A.M., Costa, G.W., May, J.B., Harmon, D.L. 2023. Influence of intra-abomasal administration of L-DOPA on circulating catecholamines and feed intake in cattle. Frontiers in Animal Science. 4. Article 1127575. https://doi.org/10.3389/fanim.2023.1127575.

Field performance of a red clover germplasm selected for increased tolerance to 2,4-D - (Peer Reviewed Journal)
Araujo, L.P., Burke, T., Dinkins, R.D., Barrett, M. 2022. Field performance of a red clover germplasm selected for increased tolerance to 2,4-D. Weed Technology. 36(6):831-837. https://doi.org/10.1017/wet.2022.89.

Conventional loose mineral with added red clover leaf (Trifolium pratense L.) reverses vasoconstriction associated with tall fescue toxicosis in steers - (Peer Reviewed Journal)
Davis, B.E., Hamilton, T.A., Johns, J.T., Harmon, D.L., Klotz, J.L., Weinert-Nelson, J.R., Goodman, J.P., May, J., Hi, H., Schrick, F.N., Flythe, M.D. 2022. Conventional loose mineral with added red clover leaf (Trifolium pratense L.) reverses vasoconstriction associated with tall fescue toxicosis in steers. Animal Feed Science and Technology. 115523. https://doi.org/10.1016/j.anifeedsci.2022.115523.

Effects of ruminal lipopolysaccharides on growth and fermentation end products of pure cultured bacteria - (Peer Reviewed Journal)
Sarmikasoglou, E., Ferrell, J.L., Vinyard, J.R., Flythe, M.D., Tuanyok, A., Faciola, A.P. 2022. Effects of ruminal lipopolysaccharides on growth and fermentation end products of pure cultured bacteria. Nature Scientific Reports. 12. Article 15932. https://doi.org/10.1038/s41598-022-20073-2.