Research Project: Antimicrobials for Biorefining and Agricultural Applications

Location: Renewable Product Technology Research

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Yeast expressing a phage endolysin reduces endogenous Clostridium perfringens ex vivo in chicken gut fluids - (Peer Reviewed Journal)
Barnas, M.R., Attuquayefio, W.D., Donovan, D.M., Skory, C.D., Hammond, R.W., Siragusa, G.R., Timmons, J.R. 2024. Yeast expressing a phage endolysin reduces endogenous Clostridium perfringens ex vivo in 21-day-old broiler chicken intestinal fluids. Avian Diseases. 68(2):129-133. https://doi.org/10.1637/aviandiseases-D-23-00088.

Developing the E. coli platform for efficient production of UMP-derived chemicals - (Peer Reviewed Journal)
Yu, L., Gao, Y., He, Y., Liu, Y., Shen, J., Liang, H., Gong, R., Duan, H., Price, N.P.J., Song, X., Deng, Z., Chen, W. 2024. Developing the E. coli platform for efficient production of UMP-derived chemicals. Metabolic Engineering. 83:61-74. https://doi.org/10.1016/j.ymben.2024.03.004.

Production of a bacteriocin like protein PEG 446 from Clostridium tyrobutyricum strain NRRL B-67062 - (Peer Reviewed Journal)
Liu, S., Lu, S.Y., Patel, M., Qureshi, N., Dunlap, C.A., Hoecker, E.C., Skory, C.D. 2024. Production of a bacteriocin like protein PEG 446 from Clostridium tyrobutyricum strain NRRL B-67062. Probiotics and Antimicrobial Proteins. https://doi.org/10.1007/s12602-023-10211-1.

The tunicamycin derivative TunR2 exhibits potent antibiotic properties with low toxicity in an in vivo Mycobacterium marinum - zebrafish TB infection model - (Peer Reviewed Journal)
Nonarath, H.J.T., Jackson, M.A., Penoske, R.M., Zahrt, T.C., Price, N.P.J., Link, B.A. 2024. The tunicamycin derivative TunR2 exhibits potent antibiotic properties with low toxicity in an in vivo Mycobacterium marinum - zebrafish TB infection model. Journal of Antibiotics. https://doi.org/10.1038/s41429-023-00694-z.

Novel Endolysin LysMP for Control of Limosilactobacillus and Lactobacillus Bacterial Contamination in Small-Scale Corn Mash Fermentation - (Peer Reviewed Journal)
Patel, M.H., Lu, S.-Y., Liu, S., Skory, C.D. 2023. Novel endolysin LysMP for control of Limosilactobacillus fermentum contamination in small-scale corn mash fermentation. Biotechnology for Biofuels and Bioproducts. 16(1):144. https://doi.org/10.1186/s13068-023-02400-5.

Precursor-directed biosynthesis and biological testing of omega-alicyclic- and neo-branched Tunicamycin N-acyl variants - (Peer Reviewed Journal)
Price, N.P., Jackson, M.A., Hartman, T.M., Bannantine, J.P., Naumann, T.A., Vermillion, K., Koch, A.A., Kennedy, P.D. 2023. Precursor-directed biosynthesis and biological testing of omega-alicyclic- and neo-branched Tunicamycin N-acyl variants. ACS Chemical Biology. https://doi.org/10.1021/acschembio.3c00324.

Saccharomyces cerevisiae surface display of endolysin LysKB317 for control of bacterial contamination in corn ethanol fermentations - (Peer Reviewed Journal)
Lu, S.Y., Liu, S., Patel, M., Glenzinski, K.M., Skory, C.D. 2023. Saccharomyces cerevisiae surface display of endolysin LysKB317 for control of bacterial contamination in corn ethanol fermentations. Frontiers in Bioengineering and Biotechnology. 11. Article 1162720. https://doi.org/10.3389/fbioe.2023.1162720.

Extractive fermentation as a novel strategy for high cell mass production of hetero-fermentative probiotic strain Limosilactobacillus reuteri - (Peer Reviewed Journal)
Selvamani, S., Ramli, S., Dailin, D.J., Natasya, K.H., Varzakas, T., Abomoelak, B., Sukmawati, D., Nurjayadi, M., Liu, S., Gupta, V.K., El Enshasy, H.A. 2022. Extractive fermentation as a novel strategy for high cell mass production of hetero-fermentative probiotic strain Limosilactobacillus reuteri. Fermentation. 8(10). Article 527. https://doi.org/10.3390/fermentation8100527.

Antibacterial property and metagenomic analysis of milk kefir - (Peer Reviewed Journal)
Liu, S., Lu, S.Y., Qureshi, N., El Enshasy, H.A., Skory, C.D. 2022. Antibacterial property and metagenomic analysis of milk kefir. Probiotics and Antimicrobial Proteins. 14:1170-1183. https://doi.org/10.1007/s12602-022-09976-8.

Milk kefir microbial compositions and two isolated cultures with antibacterial activities - (Abstract Only)
Liu, S., Lu, S.Y., Qureshi, N., El Enshasy, H.A., Skory, C.D. 2022. Milk kefir microbial compositions and two isolated cultures with antibacterial activities. [abstract]. Submitted to Society of Industrial Microbiology 72nd Annual Meeting 2022. San Francisco, CA, United States August 7-10, 2022. (https://www.simbhq.org/annual/).

Excreted antibiotics may be key to emergence of increasingly efficient antibiotic resistance in food-animal production - (Peer Reviewed Journal)
Avillan, J.J., Ahmadvand, P., Lu, S.Y., Horton, J., Liu, J., Lofgren, E., Davis, M.A., Kang, C., Call, D.R. 2022. Excreted antibiotics may be key to emergence of increasingly efficient antibiotic resistance in food-animal production. Applied and Environmental Microbiology. Article e00791-22. https://doi.org/10.1128/aem.00791-22.

Efficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system - (Peer Reviewed Journal)
Yu, L., Zhou, W., She, Y., Ma, H., Cai, Y., Jiang, M., Deng, Z., Price, N.P., Chen, W. 2021. Efficient biosynthesis of nucleoside cytokinin angustmycin A containing an unusual sugar system. Nature Communications. 12. Article 6633. https://doi.org/10.1038/s41467-021-26928-y.

Fermentative production of alternative antimicrobial peptides and enzymes - (Review Article)
Lu, S.Y., Skory, C.D., El Enshasy, H.A., Liu, S. 2021. Fermentative production of alternative antimicrobial peptides and enzymes. Biocatalysis and Agricultural Biotechnology. 37. Article 102189. https://doi.org/10.1016/j.bcab.2021.102189.

Synthesis and characterization of cellobiose-derived oligosaccharides with bifidogenic activity by glucansucrase E81 - (Peer Reviewed Journal)
Ispirli, H., Bowman, M.J., Skory, C.D., Dertli, E. 2021. Synthesis and characterization of cellobiose-derived oligosaccharides with bifidogenic activity by glucansucrase E81. Food Bioscience. 44(Part A). Article 101388. https://doi.org/10.1016/j.fbio.2021.101388.

Synthesis and characterization of Bifidogenic raffinose-derived oligosaccharides via acceptor reactions of glucansucrase E81 - (Peer Reviewed Journal)
Ispirli, H., Bowman, M.J., Skory, C.D., Dertli, E. 2021. Synthesis and characterization of Bifidogenic raffinose-derived oligosaccharides via acceptor reactions of glucansucrase E81. LWT - Food Science and Technology. 147. Article 111525. https://doi.org/10.1016/j.lwt.2021.111525.