Research Project: Molecular, Immune and Microbiome Approaches for Mitigating GI Nematode Infections of Livestock

Location: Animal Parasitic Diseases Laboratory

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Differentiation and regulation of bovine Th2 cells in vitro - (Peer Reviewed Journal)
Kandel, A., Li, L., Wang, Y., Tuo, W., Xiao, Z. 2024. Differentiation and regulation of bovine Th2 cells in vitro. Cells. 13(9). Article e13090738. https://doi.org/10.3390/cells13090738.

Phospholipid-rich krill oil promotes intestinal health by strengthening beneficial gut microbial interactions in an infectious colitis model - (Peer Reviewed Journal)
Liu, F., Smith, A.D., Wang, T.T., Pham, Q., Hou, P., Cheung, L., Yang, H., Li, R.W. 2024. Phospholipid-rich krill oil promotes intestinal health by strengthening beneficial gut microbial interactions in an infectious colitis model. Food & Function. 15(5):2604-2615. https://doi.org/10.1039/D3FO04980A.

Discovery of new broad-spectrum anti-infectives for eukaryotic pathogens using bioorganometallic chemistry - (Peer Reviewed Journal)
Lin, Y., Jung, H., Bulman, C.A., Ng, J., Vinck, R., O'Beirne, C., Moser, M.S., Tricoche, N., Peguero, R., Li, R.W., Urban, J., Le Pape, P., Pagniez, F., Moretto, M., Weil, T., Lustigman, S., Mitreva, M., Sakanari, J.A., Gassera, G. 2023. Discovery of new broad-spectrum anti-infectives for eukaryotic pathogens using bioorganometallic chemistry. Journal of Medicinal Chemistry. 66(23):15867-15882. https://doi.org/10.1021/acs.jmedchem.3c01333.

An FcRn-targeted mucosal vaccine against SARS-CoV-2 infection and transmission - (Peer Reviewed Journal)
Li, W., Wang, T., Rajendrakumar, A.M., Miao, Z., Yu, H., Acharya, G., Tuo, W., Zhu, X. 2023. An FcRn-targeted mucosal vaccine against SARS-CoV-2 infection and transmission. Nature Communications. 14(1). Article e7114. https://doi.org/10.1038/s41467-023-42796-0.

Differential correlation of transcriptome data reveals gene pairs and pathways involved in treatment of Citrobacter rodentium infection with bioactive punicalagin - (Peer Reviewed Journal)
Fleming, D.S., Liu, F., Li, R.W. 2023. Differential correlation of transcriptome data reveals gene pairs and pathways involved in treatment of Citrobacter rodentium infection with bioactive punicalagin. Molecules. 28(21). Article e28217369. https://doi.org/10.3390/molecules28217369.

Rumen microbiome dynamics and their implications in health and environment - (Peer Reviewed Journal)
Li, R.W., Moon, C.D., Morgavi, D.P. 2023. Rumen microbiome dynamics and their implications in health and environment. Frontiers in Microbiology. 14. Article e1223885. https://doi.org/10.3389/fmicb.2023.1223885.

After bone marrow transplantation, cell-intrinsic T Helper-2 (Th2) pathway promotes recipient T lymphocyte survival and regulates the graft-versus-host disease - (Peer Reviewed Journal)
Truscott, J., Guan, X., Fury, H., Atagozli, T., Metwali, A., Liu, W., Li, Y., Urban Jr, J.F., Li, R.W., Brombacher, F., Elliott, D., Blazer, B., Ince, M. 2023. After bone marrow transplantation, cell-intrinsic T Helper-2 (Th2) pathway promotes recipient T lymphocyte survival and regulates the graft-versus-host disease. Journal of Immunology. https://doi.org/10.4049/immunohorizons.2300021.

Multi-omics analysis detected multiple pathways by which pomegranate punicalagin exerts its biological effects in modulating host–microbiota interactions in murine colitis models - (Peer Reviewed Journal)
Liu, F., Smith, A.D., Wang, T.T., Pham, Q., Yang, H., Li, R.W. 2023. Multi-omics analysis detected multiple pathways by which pomegranate punicalagin exerts its biological effects in modulating host–microbiota interactions in murine colitis models. Food & Function. 14:3824. https://doi.org/10.1039/D3FO00286A.

Ellagitannin punicalagin disrupts the pathways related to bacterial growth and affects multiple pattern recognition receptor signaling by acting as a selective histone deacetylase inhibitor - (Peer Reviewed Journal)
Liu, F., Smith, A.D., Wang, T.T., Pham, Q., Yang, H., Li, R.W. 2023. Ellagitannin punicalagin disrupts the pathways related to bacterial growth and affects multiple pattern recognition receptor signaling by acting as a selective histone deacetylase inhibitor. Journal of Agricultural and Food Chemistry. 71(12):5016-5026. https://doi.org/10.1021/acs.jafc.2c08738.

Biological pathways via which the anthocyanin malvidin alleviated the murine colitis induced by Citrobacter rodentium - (Peer Reviewed Journal)
Liu, F., Smith, A.D., Wang, T.T., Pham, Q., Cheung, L., Yang, H., Li, R.W. 2022. Biological pathways via which the anthocyanin malvidin alleviated the murine colitis induced by Citrobacter rodentium. Food & Function. 14(2):1048-1061. https://doi.org/10.1039/D2FO02873E.

Recent advances in developing butyrogenic functional foods to promote gut health - (Review Article)
Zhang, M., Li, R.W., Yang, H., Tan, Z., Liu, F. 2022. Recent advances in developing butyrogenic functional foods to promote gut health. Critical Reviews in Food Science and Nutrition. 1-22. https://doi.org/10.1080/10408398.2022.2142194.

Horizontal gene transfer provides insights into the deep evolutionary history and biology of Trichinella - (Literature Review)
Zarlenga, D., Thompson, P.C., Mitreva, M., Rosa, B., Hoberg, E. 2022. Horizontal gene transfer provides insights into the deep evolutionary history and biology of Trichinella. Food and Waterborne Parasitology. https://doi.org/10.1016/j.fawpar.2022.e00155.