Author
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Brown, Fred |
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Submitted to: Food Animal Disease Research Conference Proceedings
Publication Type: Book / Chapter Publication Acceptance Date: 4/22/1996 Publication Date: N/A Citation: N/A Interpretive Summary: This invited review article describes the development of veterinary vaccines against virus diseases. It is a chapter in a book published by the Food and Agriculture Organization of the United Nations, Rome, 1997 entitled, vaccine manual: the production and quality control of veterinary vaccines for use in developing countries. Technical Abstract: Vaccination is a major weapon in the control of many viral diseases of humans and their domestic and pet animals. There is no doubt that vaccines have made an enormous impact on the health and consequently the productivity of the recipients. Although this chapter concentrates on vaccines which are used in domestic livestock, where necessary it draws analogies with information involving other species. In addition, an overview on the present state of vaccine development must necessarily review what has gone before and, with advantage, should also look to the future. Consequently, this chapter contains references to products that were made in the past, including the way in which they were improved to provide the vaccines in current use, and outlines the possibilities of entirely new products which molecular biololgy offers. Although it is always dangerous to make predictions, one can be certain that the methods for preparing vaccines will improve. It is also possible and even likely that the methods will change radically as we learn more about the immune response at the molecular level and apply recombinant DNA technology to produce and present to the host only those parts of the virus that are required to provide protection. |
