Skip to main content
ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Ruminant Diseases and Immunology Research » Research » Publications at this Location » Publication #106039
Title: EFFECT OF MASTECTOMY ON PLASMA CALCIUM AND VITAMIN A AND E METABOLISM IN THE PERIPARTURIENT DAIRY COW

Author
item Horst, Ronald
item KIMURA, KAYOKO - IOWA STATE UNIV., AMES
item Goff, Jesse

Submitted to: International Conference on Production Diseases in Farm Animals
Publication Type: Abstract Only
Publication Acceptance Date: 8/25/1998
Publication Date: N/A
Citation: N/A

Interpretive Summary:

Technical Abstract: Plasma conc of Ca and vit A (retinol) and E (tocopherol) decrease at calving. This change is attributed to loss of these substances to the maammary gland and colostrum. Using older Jersey cows fed a high cation diet that were intact or mastectomized (MastX) plasma conc of Ca, tocopherol, and retinol and its retinoic acid (RA) metabolites (All-tran n 9-cis RA, 13-cis RA and 9,13-dicis RA) were monitored during the periparturient period. Retinol is the precursor to All-trans and 9-cis which bind specific cellular receptors to mediate biological actions attributed to vit A. 9,13-Dicis RA can be isomerized to 9-cis RA in bod tissues. Plasma Ca conc fell at calving in intact cows and all develope milk fever. No significant change in plasma Ca was observed in the Mast cows during the periparturient period. Two wk before parturition plasma retinol and tocopherol conc were 142 ng/ml and 1.84 ug/ml and declined a a parturition in both MastX and intact cows. The retinol and tocopherol nadirs were 32 and 57% of precalving levels in intact cows and 56 and 90 of precalving levels in MastX cows. Plasma 9-cis RA was greater in inta cows than MastX cows during the periparturient period but was not affect by parturition in either group. Plasma All-trains and 13-cis RA conc we similar in both intact and MastX cows and were not affected by parturition. Plasma 9,13-dicis RA was less than .5 ng/ml in both groups of cows prior to calving. However, after calving 9,13-dicis RA conc increased to 3.5 ng/ml in intact cows but did not increase in MastX cows Milk production accounts for a major portion of the tocopherol and half the retinol decline. The mammary gland plays a major role in appearance of 9-cis RA and 9,13-dicis retinoic acid in plasma of postparturient cow