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ARS Home » Research » Publications at this Location » Publication #110824
Title: FROM GENE TO PROTEIN: WHAT IS NEW IN MAREK'S DISEASE

Author
item Silva, Robert
item Lee, Lucy
item Kutish, Gerald

Submitted to: World Poultry Congress Proceedings
Publication Type: Review Article
Publication Acceptance Date: 8/20/2000
Publication Date: N/A
Citation: N/A

Interpretive Summary:

Technical Abstract: Just within the later part of 1999 and early 2000, our knowledge of Marek's disease virus (MDV) genome structure and organization has dramatically expanded. This has largely occurred as a result of massive efforts to DNA sequence representative strains from each of the three MDV serotypes. Since the DNA sequence of viruses from the three MDV serotypes should significantly enhance our understanding of MDV pathogenesis, this review will focus on MDV genome organization. Rather than reviewing the new developments in understanding pathogenesis, vaccinal protection or epidemeology of Marek's disease, we will limit this report to describing recent findings on selected genes that have been well studied (or deserve further research) and the new knowledge regarding the overall MDV genome organization.