Author
Porter, James | |
Vesonder, Ronald | |
RICHARD, J - ARS/MYCOT RES/MWA/RETIRED | |
COLE, R - PEANT RES/SAA/ARS/RETIRED |
Submitted to: Paul Nelson Memorial Symposium
Publication Type: Proceedings Publication Acceptance Date: 5/5/2000 Publication Date: N/A Citation: N/A Interpretive Summary: Developments in mycotoxicology have been very rapid over the last four decades. This has been especially true of the discovery of secondary, biologically active metabolites of Fusarium species, which include antibiotics, phytotoxins, and mycotoxins. Pre- and post-harvest crop deprivation by Fusarium species and contamination of food commodities with Fusarium mycotoxins is recognized worldwide as major agricultural problems with significant economic, international trade, and human and animal health implications. In this regard, the significant mycotoxins associated with major health problems in animals and humans are zearalenone, deoxynivalenol, and the fumonisins, all of which are routinely monitored in food and feed products. "Other significant Fusarium mycotoxins" which further represent the diverse chemistry, distribution and biological effects of Fusarium- contaminated corn, wheat, sorghum, and other agricultural commodities are: fusaric acid, moniliformin, fusaproliferin, beauvericin, fusarochromanone, fusarins, and wortmannin. The diverse structures and equally diverse biological activities of the Fusarium toxins are discussed with reference to the significance of co-occurring mycotoxins in the food and feed supply. Detailed interactive and synergistic effects are also outlined. This chapter is a collaborative effort by scientists who have made significant contributions to the understanding of Fusarium mycotoxins. Technical Abstract: No abstract for this Proceeding. |