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ARS Home » Southeast Area » Stuttgart, Arkansas » Harry K. Dupree Stuttgart National Aquaculture Research Cntr » Research » Publications at this Location » Publication #152746

Title: LABORATORY EFFICACY OF AMOXICILLIN FOR CONTROL OF STREPOCOCCUS INIAE INFECTION IN HYBRID STRIPED (SUNSHINE) BASS

Author
item Darwish, Ahmed

Submitted to: Aquaculture America Conference
Publication Type: Abstract Only
Publication Acceptance Date: 8/5/2003
Publication Date: 3/1/2004
Citation: Darwish, A.M. 2004. Laboratory efficacy of amoxicillin for control of strepococcus iniae infection in hybrid striped (sunshine) bass [abstract]. In: Aquaculture America Conference. p. 146.

Interpretive Summary:

Technical Abstract: Experimental trial was performed to evaluate the efficacy of amoxicillin (AMX) in controlling Streptococcus iniae infection in hybrid striped bass (Morone saxatilis male ´ Morone chrysops female). Minimum-inhibitory concentration studies of AMX against multiple S. iniae isolates showed a sensitivity range of 0.0156 to 0.5 mg/mL. Amoxicillin dose levels tested were 30, 50, 80 and 120 mg active ingredient per kilogram of fish body weight per day. Administration of medicated feed started 1 d after infection by waterborne exposure to S. iniae and continued for 8 consecutive days, followed by 15 d post-treatment observation. The AMX increased the survival rate from 1 % in the infected non-infected group to a survival average of 95 % in the fish groups receiving AMX at different dose with no significant difference among the AMX medicated groups. Survivors of the infection were not detected to be carriers of the bacteria (negative bacterial isolation).