PROTEIN PRODUCTION IN AUREOBASIDIUM PULLULANS

Authors: LI, XIN LIANG; LJUNGDAHL, G. - ATHENS, GA

Submitted to: Patent Application
Publication Type: Other
Publication Acceptance Date: 6/15/2000
Publication Date: 3/18/2003
Citation: Li, X., Ljungdahl, G. 2003. Protein production in Aureobasidium pullulans. U.S. Patent 6,534,286.

Interpretive Summary:

Technical Abstract: The present disclosure provides methods and DNA molecules for the synthesis of heterologous proteins in the fungus Aurebasidium pullulans either intracellularly or with secretion out of the cells using a regulated xylanase promoter and for secreted protein synthesis, a signal sequence. Further described are kits containing host cells for recombinant protein production, a vector containing an XynA transcription regulatory sequence, and instructions for using the vector to transform the host cells.