PROTEIN NOMENCLATURE REPORT: SIXTH REVISION

Authors: Farrell Jr, Harold; JIMENEZ-FLORES, RAFAEL - DEPT.FOOD SCI/CALPOLY; BLACK, GREG - GALA DESIGN,MIDDLETON,WI; Brown, Eleanor - Ellie; BUTLER, J. - DEPT.MICROBIO/U OF IOWA; CREAMER, L. - PALMERSTON,NEW ZEALAND; HOLLAR, CAROL - M&M MARS/ELIZABETHTOWN,PA; NG-KWAI-HANG, K. - DEPT.ANIMAL SCI/MCGILL U.; SWAISGOOD, H. - DEPT.FOOD SCI/NC STATE U.

Submitted to: Journal of Dairy Science
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 1/14/2004
Publication Date: 4/1/2004
Citation: Farrell, H.M., Jimenez-Flores, R., Bleck, G.T., Brown, E.M., Butler, J.E., Creamer, L.K., Hicks, C.L., Hollar, C.M., Ng-Kwa-Hang, K.F., Swaisgood, H.E. 2004. Nomenclature of the proteins of cows' milk - Sixth Revision. J. Dairy Science. Vol. 87:p.1641-1674.

Interpretive Summary: n/a

Technical Abstract: The report of the American Dairy Science Association Committee on the Nomenclature, Classification, and Methodology of Milk Proteins reviews changes in the nomenclature of milk proteins necessitated by recent advances of our knowledge of milk proteins. Identification of the major caseins and whey proteins continues to be based upon their primary structures. Nomenclature of the immunoglobulins consistent with new international standards has been developed, and all bovine immunoglobulins have been characterized at the molecular level. Other significant findings related to nomenclature and protein methodology re: elucidation of several new genetic variants of the major milk proteins; establishment by sequencing techniques and sequence alignment of the bovine caseins and whey proteins as the reference point for the nomenclature of all homologous milk proteins; crystallographic studies have been completed for the major whey proteins; and advances in the study of the whey protein lactoferrin allow it to be added to the list of fully characterized milk proteins.