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Title: LINKAGE DISEQUILIBRIUM IN FOUR SOYBEAN POPULATIONS

Author
item HYTEN, DAVID
item SONG, QIJIAN - CHINA
item CREGAN, PERRY

Submitted to: Plant and Animal Genome VX Conference Abstracts
Publication Type: Abstract Only
Publication Acceptance Date: 10/30/2003
Publication Date: 10/30/2003
Citation: Hyten, D.L., Song, Q., Cregan, P.B. 2003. Linkage disequilibrium in four soybean populations. Plant and Animal Genome Abstracts [abstract]. Abstract P534.

Interpretive Summary:

Technical Abstract: Linkage disequilibrium (LD) is the "non-random association of alleles" and can be utilized through association analysis to discover quantitative trait loci (QTL). If a population has extensive LD few markers will be needed to scan the whole genome for QTL but the positions of these QTL will not be well defined. Conversely, in a population with limited LD genetic factors can be fine mapped. Our goal was to provide an initial assessment of LD in four distinct soybean populations: Glycine soja (GS) the wild soybean, Asian G. max (AGM), N. Am. cultivar ancestors (NAA), and N. Am. public cultivars released in the 1980s (NAP). Multiple fragments throughout a 500 kb region were sequenced. The NAA population has the least LD decline in the 500kb fragment, while LD declines rapidly in the GS population. LD is extensive in the AGM population but did start to show some decline at distances greater than 350 kbp. The NAA population includes ancestors that contributed 86% of the germplasm pool from which the NAP were developed. In this study the NAP population had more rapid LD decline than the NAA population which could be due to several generations of hybridization during cycles of breeding performed since the introduction of G. max to N. Am. The four populations all differed in their degree of LD decline. These differences in LD could make genetic association analysis feasible including whole genome scans in populations similar to the AGM and the NAP while fine mapping of genetic factors may be possible in G. soja given the lower level of LD.