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Title: GENOMIC DIFFERENCES BETWEEN PT4 AND PT13A SALMONELLA ENTERITIDIS

Author
item PORWOLLIK, STEPHEN - KIMMEL CANCER CTR-CA
item Frye, Jonathan
item MCCLELLAND, MICHAEL - KIMMEL CANCER CTR-CA
item Guard, Jean

Submitted to: United States Animal Health Association Proceedings
Publication Type: Proceedings
Publication Acceptance Date: 7/30/2004
Publication Date: 10/24/2004
Citation: Porwollik, S., Frye, J.G., Mcclelland, M., Bouldin, J.G. 2004. Genomic differences between pt4 and pt13a salmonella enteritidis. United States Animal Health Association Proceedings. p. 510-511

Interpretive Summary: Not required.

Technical Abstract: Recent advances in nucleic acid microarray technology now make it possible to directly compare PT13a S. enteritidis in DNA-DNA hybridization assays to the complete genomes of Salmonella typhimurium LT2 and Salmonella enteritidis PT4 in order to detect how phage type correlates with genomic organization. These proceedings are a first report on bacteriophage content of S. enteritidis phage types 4 and 13a, which are representative members of the two main phage lineages of this important cause of food borne illness. Results were that phage specific to each of the lineages were identified. This research was made possible by collaboration between the Wellcome Trust Sanger Center, the Sidney Kimmel Cancer Institute and USDA.