Author
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Lynn, Dwight |
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Submitted to: Methods in Molecular Biology
Publication Type: Book / Chapter Publication Acceptance Date: 6/29/2005 Publication Date: N/A Citation: N/A Interpretive Summary: Insect cell lines are commonly used in research and product development by hundreds of government, university and industry facilities around the world. This is especially true in insect virus research, where they can be used for production of biopesticides or recombinant proteins. No listing of available lines has been made for several years. This chapter provides such a list and also details their known susceptibilities to insect viruses. This information will be of interest to scientists involved in any aspect of insect cell and virus research or development for determining appropriate cell lines for use in their project. Technical Abstract: Early in the history of insect cell culturing, researchers in the field began meeting at three to four year intervals at International Conferences on Invertebrate Tissue Culture. The first of these was held in Montpellier, France in 1962, which, perhaps not coincidentally, was the year that the first continuous insect cell lines were described in the literature (1). In the 1970’s and 80’s, W. Frederick Hink prepared compilations of insect cell lines (2-6) that were included in the proceedings from several of the subsequent International Conferences. His lists form the backbone of the listing included in this chapter. Unfortunately, the last of his compilations was published fifteen years ago, so I’ve performed a literature search for publications since that time. In addition to details on the insect species, designation of the resulting cell lines, and tissue source used, I’ve also provided details on the susceptibility to baculoviruses where they are known. |
