RESPONSE OF PLASMA GLUCOSE AND INSULIN AFTER LUNCH FOLLOWING A TOLERANCE CONTAINING DIFFERENT LEVELS OF B-GLUCAN.

Authors: BEHALL, KAY; SCHOLFIELD, DANIEL - USDA, ARS, NAL; HALLFRISCH, JUDITH - DHPL RETIRED

Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 8/2/2005
Publication Date: 10/1/2005
Citation: Behall, K.M., Scholfield, D.J., Hallfrisch, J. 2005. Response of plasma glucose and insulin after lunch following a tolerance containing different levels of b-glucan. Meeting Abstract. Journal of the American College of Nutrition. 24:432.

Interpretive Summary: None

Technical Abstract: Consumption of foods containing soluble fiber has been reported to lower blood glucose and insulin levels after the meal. This study sought to determine if the reduced glycemic response continued after the next meal. After institutional review and approval, 10 control and 10 overweight men (average BMI 24 vs 29, 25-56 y) were fed the same controlled diet for 2 days before each tolerance meal containing 75 g available carbohydrate. On day three, fasting subjects consumed glucose or muffins containing 0.1, 2.4 or 4.8 g beta glucan per meal. Lunch was consumed 4 h after the morning meal. Overweight subjects had significantly higher mean glucose (6.0 vs 5.5 mmol/L) and insulin (304 vs 181 mmol/L) concentrations than controls. As anticipated, peak glucose and insulin responses and areas under the curve (AUC) were significantly lower after muffins containing 4.8 beta glucan compared to glucose alone. One and 2 h after lunch (5 and 6 h after morning meal), glucose and insulin concentrations and AUC were significantly lower after all muffins compared to glucose alone, with no statistically significant differences between the three muffins. Compared to glucose alone, a morning meal containing complex carbohydrate had a greater impact on glycemic response after lunch than the presence of beta glucan in the meal.