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Title: HIGH DENSITY ESTS BASED BOVINE PHYSICAL MAPS AND THEIR USE TO CONSTRUCT COMPARATIVE MAPS AND INFORM THE BOVINE GENOME SEQUENCE ASSEMBLY

Author
item WILLIAMS, JOHN - ROSLIN INST. SCOTLAND
item AERTS, JAN - ROSLIN INST. SCOTLAND
item LAW, ANDY - ROSLIN INST. SCOTLAND
item JANN, OLIVER - ROSLIN INST. SCOTLAND
item JANITZ, MICHAL - MAX-PLANCK INST. GERMANY
item HENNIG, STEFFEN - MAX-PLANCK INST. GERMANY
item EGGEN, ANDRE - INRA-CRJ FRANCE
item FLORIOT, SANDRINE - INRA-CRJ FRANCE
item AJMONE-MARSAN, PAOLO - UNIVERSITA CATTOLICA ITAL
item MILANSE, ELISABETA - UNIVERSITA CATTOLICA ITAL
item VALENTINI, ALESSIO - UNIV. DELLA TUSCIA ITALY
item MARCHITELLI, CINZIA - UNIV. DELLA TUSCIA ITALY
item MCKAY, STEPHANIE - UNIV. OF ALBERTA CANADA
item PRASAD, APARNA - UNIV. OF ALBERTA CANADA
item YU, JODY - UNIV. OF ALBERTA CANADA
item MOORE, STEPHEN - UNIV. OF ALBERTA CANADA
item DROGEMULLER, CORD - INST. FOR ANIMAL BREEDING
item Connor, Erin
item Sonstegard, Tad
item Stone, Roger
item Smith, Timothy

Submitted to: Plant and Animal Genome VX Conference Abstracts
Publication Type: Abstract Only
Publication Acceptance Date: 11/14/2005
Publication Date: 1/14/2006
Citation: Williams, J.L., Aerts, J., Law, A., Jann, O., Janitz, M., Hennig, S., Eggen, A., Floriot, S., Ajmone-Marsan, P., Milanse, E., Valentini, A., Marchitelli, C., Mckay, S., Prasad, A., Yu, J., Moore, S.S., Drogemuller, C., Connor, E.E., Sonstegard, T.S., Stone, R.T., Smith, T.P. 2006. High density ESTs based bovine physical maps and their use to construct comparative maps and inform the bovine genome sequence assembly[abstracat]. Plant and Animal Genome XIV:55. Number W214.

Interpretive Summary:

Technical Abstract: The 3000 rad bovine whole genome radiation hybrid panel and bovine BAC libraries have been used to construct an integrated physical map of the bovine genome, which will contribute to the final assembly of the bovine genome sequence. The RH map now contains more than 4000 markers, the majority of which are genes or ESTs. The draft bovine sequence was used to extend sequence information for the markers and construct detailed comparative maps. Many of the markers included in the RH map have been used to identify BAC clones derived from INRA and CHORI BAC libraries, and have been used to align the whole genome BAC contig with the RH map and hence the linkage map. BAC contigs falling within gaps in the bovine sequence will be used to derive sequence to fill gaps in the genome sequence.