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Title: APPLICATION OF DEFENSE PEPTIDES FOR CONTROL OF SOYBEAN RUST

Author
item FANG, Z - UNIVERSITY OF MISSOURI
item SCHMIDT, F - UNIVERSITY OF MISSOURI
item ENGLISH, J - UNIVERSITY OF MISSOURI
item STACEY, G - UNIVERSITY OF MISSOURI
item Cooper, Bret

Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 3/30/2006
Publication Date: 3/30/2006
Citation: Fang, Z., Schmidt, F.J., English, J.T., Stacey, G., Cooper, B. 2006. Application of defense peptides for control of soybean rust [abstract]. National Academy of Sciences Sackler Colloquium, Washington, DC. p. 14.

Interpretive Summary:

Technical Abstract: Proteins and other molecules on the surface of a fungal pathogen contribute to the growth and development of the organism or provide a means of monitoring and detecting environmental signals that contribute to development. Consequently, cell-surface factors represent significant targets for pathogen disruption by inhibitory antagonistic molecules such as defense peptides. We have used combinatorial, phage-display technologies to select peptides with high affinity for surface or other cellular components critical to the function of diverse plant and human pathogens. Among these pathogens, we have recently applied these technologies to select peptides that interact and disrupt development of uredospores of Uromyces appendiculatus, the causal agent of common bean rust. Based on initial success with this model organism, we are applying combinatorial technologies for selection of peptides that should disrupt development and pathogenesis of Phakopsora pachyrhizi.