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ARS Home » Plains Area » Fargo, North Dakota » Edward T. Schafer Agricultural Research Center » Food Animal Metabolism Research » Research » Publications at this Location » Publication #235636
Title: Fate of glucuronide conjugated estradiol in the environment

Author
item SHRESTHA, SUMAN - NORTH DAKOTA STATE UNIV
item CASEY, FRANCIS - NORTH DAKOTA STATE UNIV
item Hakk, Heldur
item Larsen, Gerald
item Smith, David
item PADMANABHAN, G - NORTH DAKOTA STATE UNIV

Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 9/3/2008
Publication Date: 1/6/2009
Citation: Shrestha, S.L., Casey, F.X., Hakk, H., Larsen, G.L., Smith, D.J., Padmanabhan, G. 2009. Fate of Glucuronide Conjugated Estradiol in the Environment [Abstract]. In: Proceedings of American Society of Civil Engineers - Environmental and Water Resources Institute Conference, January 5-7, 2009, Bangkok, Thailand.

Interpretive Summary:

Technical Abstract: The fate and transport of conjugated reproductive hormones, which are polar compared to parent hormones, are little understood. Laboratory bench-scale soil (Hamar; Sandy, mixed, frigid typic Endoaquolls) sorption studies were conducted using [14C] 17ß-estradiol-3-glucuronide for a range of concentrations (0.36 – 29.70 µg mL-1). A rapid decrease in total 14C aqueous concentration was observed in the first 48 h of the study, but then remained constant through end of the experiment (672 h). The first order rate constants ranged from 0.02 to -0.04/h for the various initial concentrations, where higher rate constants were generally observed for the lower concentrations. Mass balance of the total radioactivity distributed in aqueous and sorbed phase through time was near 100% at all times which shows that the applied radioactivity was accounted for and was either in the sorbed or in aqueous phase. Thus, the first 48 h after urinary elimination and subsequent introduction into soil-water system may be critical for E2G being transported to receiving water systems. However, speciation of component radioactivity within 48 hours needs to be determined.