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ARS Home » Midwest Area » Peoria, Illinois » National Center for Agricultural Utilization Research » Mycotoxin Prevention and Applied Microbiology Research » Research » Publications at this Location » Publication #269571
Title: Physicochemical study on interactions between T-2 and HT-2 toxin derivatives and cyclodextrins

Author
item VENTRELLA, ANDREA - University Of Bari
item LONGOBARDI, FRANCESCO - University Of Bari
item AGOSTIANO, ANGELA - University Of Bari
item PASCALE, MICHELANGELO - Institute Of Food Science And Technolgoy
item LIPPOLIS, VINCENZO - Institute Of Food Science And Technolgoy
item Maragos, Chris
item CATUCCI, LUCIA - University Of Bari

Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: 11/4/2011
Publication Date: 11/4/2011
Citation: Ventrella, A., Longobardi, F., Agostiano, A., Pascale, M., Lippolis, V., Maragos, C.M., Catucci, L. 2011. Physicochemical study on interactions between T-2 and HT-2 toxin derivatives and cyclodextrins. II European Conference on Cyclodextrins.

Interpretive Summary:

Technical Abstract: Physicochemical interactions occurring between fluorescent anthracene derivatives of T-2 and HT-2 toxins and different cyclodextrins (CDs) were investigated in aqueous solutions by means of UV-Vis absorption, fluorescence emission, and Dynamic Light Scattering. Binding constant values and physicochemical parameters were determined showing '-CDs to give the strongest inclusion reactions with both T-2 and HT-2 derivatives. Such interactions were found to be fundamentally enthalpy driven. Among '-CDs, dimethyl-'-CD (DIMEB) was found to induce the greatest fluorescence intensity enhancement. The findings of this work could be of great interest to improve mycotoxin detection by spectroscopic techniques