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Submitted to: Meeting Abstract
Publication Type: Abstract Only Publication Acceptance Date: 3/6/2014 Publication Date: 4/11/2014 Citation: Xu, J., Liu, Z., Kim, S., Liu, S.X. 2014. Rheological properties of a biological thermo-responsive hydrogel prepared from vegetable oil. Meeting Abstract. Interpretive Summary: Technical Abstract: Hydrogel is a colloidal gel in which water is the dispersion medium. The unique properties of hydrogels make this kind of materials have many utilization potentials, such as drug delivery, gene therapy, wound care products, breast implant materials, cosmetic products, and tissue engineering. Hydrogels produced from biopolymers and/or natural sources have particular superiority in vivo applications since they are more likely biodegradable, biocompatible, bioresorbable, and even edible. The rheological properties of a newly developed biological thermo-responsive hydrogel made from vegetable oil were investigated. The material named HPSO-HG is a hydrolytic product of polymerized soybean oil (PSO). HPSO-HG is a thermo-responsive gel, and it exhibited viscoelastic behavior above 2% (wt.%) at room temperature and viscous fluid behavior at 55°C. The viscoelastic properties of HPSO-HG were strongly dependent on concentration. The analysis of modulus and concentration dependence and stress relaxation measurement indicated that HPSO-HG was a physical gel meaning the cross-linkers between the molecules were physical junctions. HPSO-HG hydrogel also showed fast initial partially recovery of its viscoelastic properties after being subject to a mechanical shear disruption. The function and behavior of the HPSO-HG hydrogel suggest that this biomaterial be a potential candidate for applications in cosmetic products, drug delivery, and wound skin care products. |
