Author
![]() |
WU, ALBERT - Department Of Energy Joint Genome |
![]() |
PROCHNIK, SIMON - Department Of Energy Joint Genome |
![]() |
JENKINS, JERRY - Hudsonalpha Institute For Biotechnology |
![]() |
SALSE, JEROME - Institut National De La Recherche Agronomique (INRA) |
![]() |
HELLSTEN, UFFE - Department Of Energy Joint Genome |
![]() |
MURAT, FLORENT - Institut National De La Recherche Agronomique (INRA) |
![]() |
PERRIER, XAVIER - Centro De Cooperation Internationale En Recherche Agronomique Pour Le Development (CIRAD) |
![]() |
RUIZ, MANUEL - Centro De Cooperation Internationale En Recherche Agronomique Pour Le Development (CIRAD) |
![]() |
SCALABRIN, SIMONE - Istituto Di Genomica Applicata (IGA) |
![]() |
TEROL, JAVIER - Non ARS Employee |
![]() |
TAKITA, MARCO - Sylvio Moreira Citrus Research |
![]() |
ROKSAR, DANIEL - Department Of Energy Joint Genome |
![]() |
LABADIE, KARINE - Non ARS Employee |
![]() |
PAULAIN, JULIE - Non ARS Employee |
![]() |
CAULOUX, ARNAUD - Non ARS Employee |
![]() |
JABBARI, KAMEL - Non ARS Employee |
![]() |
CATTONARO, FEDERICA - Istituto Di Genomica Applicata (IGA) |
![]() |
FABBRO, CRISTIAN - Istituto Di Genomica Applicata (IGA) |
![]() |
PINOSIO, SARA - Istituto Di Genomica Applicata (IGA) |
![]() |
ZUCCOLO, ANDREA - Istituto Di Genomica Applicata (IGA) |
![]() |
CHAPMAN, JARROD - Department Of Energy Joint Genome |
![]() |
GRIMWOOD, JANE - Hudsonalpha Institute For Biotechnology |
![]() |
TADEO, FRANCISCO - Valencian Institute For Agricultural Research |
![]() |
ESTORNELL, LEANDRO - Valencian Institute For Agricultural Research |
![]() |
MUNOZ-SANZ, JUAN - Valencian Institute For Agricultural Research |
![]() |
IBANEZ, VICTORIA - Valencian Institute For Agricultural Research |
![]() |
HERRERO-ORTEGA, AMPARO - Valencian Institute For Agricultural Research |
![]() |
ALEZA, PABLO - Valencian Institute For Agricultural Research |
![]() |
PEREZ-PEREZ, JULIAN - Non ARS Employee |
![]() |
RAMON, DANIEL - Non ARS Employee |
![]() |
BRUNEL, DOMINIQUE - Non ARS Employee |
![]() |
LURO, FRANCOIS - Institut National De La Recherche Agronomique (INRA) |
![]() |
Chen, Chunxian |
![]() |
FARMERIE, WILLIAM - University Of Florida |
![]() |
DESANY, BRIAN - Roche Diagnostics |
![]() |
KODIRA, CHINNAPPA - Roche Diagnostics |
![]() |
MOHIUDDIN, MOHAMMED - Roche Diagnostics |
![]() |
HARKINS, TIM - Roche Diagnostics |
![]() |
FREDRIKSON, KARIN - Roche Diagnostics |
![]() |
BURNS, PAUL - Georgia Institute Of Technology |
![]() |
LOMSADZE, ALEXANDRE - Georgia Institute Of Technology |
![]() |
BORODOVSKY, MARK - Georgia Institute Of Technology |
![]() |
REFORGIATO, GIUSEPPE - Non ARS Employee |
![]() |
FREITA-ASTUA, JULIANA - Sylvio Moreira Citrus Research |
![]() |
QUETIER, FRANCIS - Non ARS Employee |
![]() |
NAVARRO, LUIS - Valencian Institute For Agricultural Research |
![]() |
ROOSE, MIKEAL - University Of California |
![]() |
WINCKER, PATRICK - Non ARS Employee |
![]() |
SCHMUTZ, JEREMY - Hudsonalpha Institute For Biotechnology |
![]() |
MORGANTE, MICHELE - Istituto Di Genomica Applicata (IGA) |
![]() |
MACHADO, MARCOS - Sylvio Moreira Citrus Research |
![]() |
TALON, MANUEL - Non ARS Employee |
![]() |
JAILLON, OLIVIER - Non ARS Employee |
![]() |
OLLITRAULT, PATRICK - Centro De Cooperation Internationale En Recherche Agronomique Pour Le Development (CIRAD) |
![]() |
GMITTER, FREDERICK - University Of Florida |
Submitted to: Nature Biotechnology
Publication Type: Peer Reviewed Journal Publication Acceptance Date: 4/4/2014 Publication Date: 6/8/2014 Citation: Wu, A.G., Prochnik, S., Jenkins, J., Salse, J., Hellsten, U., Murat, F., Perrier, X., Ruiz, M., Scalabrin, S., Terol, J., Takita, M.A., Roksar, D., Labadie, K., Paulain, J., Cauloux, A., Jabbari, K., Cattonaro, F., Fabbro, C.D., Pinosio, S., Zuccolo, A., Chapman, J., Grimwood, J., Tadeo, F.R., Estornell, L.H., Munoz-Sanz, J.V., Ibanez, V., Herrero-Ortega, A., Aleza, P., Perez-Perez, J., Ramon, D., Brunel, D., Luro, F., Chen, C., Farmerie, W.G., Desany, B., Kodira, C., Mohiuddin, M., Harkins, T., Fredrikson, K., Burns, P., Lomsadze, A., Borodovsky, M., Reforgiato, G., Freita-Astua, J., Quetier, F., Navarro, L., Roose, M., Wincker, P., Schmutz, J., Morgante, M., Machado, M.A., Talon, M., Jaillon, O., Ollitrault, P., Gmitter, F. 2014. Sequencing of diverse mandarin, pummelo and orange genomes reveals complex history of admixture during citrus domestication. Nature Biotechnology. 32(7):656-662. Interpretive Summary: Diverse types of commercial citrus cultivars were domesticated several thousand years ago in Southeast Asia and spread globally. According to limited morphologic traits and molecular marker data, most citrus types are presumably originated from interspecific hybridization and multi-generational introgression with different wild ancestral species. However, it remains controversial how main modern varieties evolved from what ancestral species. This study is to sequence and compare the genomes of main citrus types, including mandarins, pummelos, sweet oranges and sour oranges. The results help understand taxonomic relationship from genomic phylogenetic perspectives and facilitate sequence-directed genetic improvement in the crop. Technical Abstract: Cultivated citrus are selections from, or hybrids of, wild progenitor species whose identities and contributions to citrus domestication remain controversial. Here we sequence and compare citrus genomes—a high-quality reference haploid clementine genome and mandarin, pummelo, sweet-orange and sour-orange genomes—and show that cultivated types derive from two progenitor species. Although cultivated pummelos represent selections from one progenitor species, Citrus maxima, cultivated mandarins are introgressions of C. maxima into the ancestral mandarin species Citrus reticulata. The most widely cultivated citrus, sweet orange, is the offspring of previously admixed individuals, but sour orange is an F1 hybrid of pure C. maxima and C. reticulata parents, thus implying that wild mandarins were part of the early breeding germplasm. A Chinese wild ‘mandarin’ diverges substantially from C. reticulata, thus suggesting the possibility of other unrecognized wild citrus species. Understanding citrus phylogeny through genome analysis clarifies taxonomic relationships and facilitates sequence-directed genetic improvement. |