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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Ruminant Diseases and Immunology Research » Research » Publications at this Location » Publication #318834
Title: Genome sequences of Mannheimia haemolytica serotype A2 isolates D171 and D35, recovered from bovine pneumonia

Author
item Hauglund, Melissa
item Tatum, Fred
item Bayles, Darrell
item MAHESWARAN, SAMUEL - University Of Minnesota
item Briggs, Robert

Submitted to: Genome Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 2/2/2015
Publication Date: 3/12/2015
Publication URL: http://handle.nal.usda.gov/10113/61194
Citation: Hauglund, M.J., Tatum, F.M., Bayles, D.O., Maheswaran, S.K., Briggs, R.E. 2015. Genome sequences of Mannheimia haemolytica serotype A2 isolates D171 and D35, recovered from bovine pneumonia. Genome Announcements. 3(2):1e00093-15. DOI 10.1128/genomeA.00093-15.

Interpretive Summary: Mannheimia haemolytica is a costly bacterial causative agent of pneumonia (shipping fever) in cattle. This bacterium responds to stress and concurrent respiratory viral infection by greatly elevated levels of infection in cattle nasal passages. Although serotypes 1, 2, and 6 are common among in cattle nasal passages, only serotypes 1 and 6 so respond and that is likely why these latter serotypes predominate in pneumonic disease. Whole genome sequencing was conducted to define the differences between the serotypes. This report describes the genomes of two serotype 2 strains. Comparison of these with the genomes of serotypes 1 and 6 will allow scientists to focus on factors related to the stress response and potentially lead to improved disease intervention strategies.

Technical Abstract: Here, we report two genomes, one complete and one draft, from isolates of serotype A2 Mannheimia haemolytica recovered from pneumonic bovine lung.