Author
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CHA, JAE-YUL - Gyeongsang National University |
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HAN, SANGJO - Gyeongsang National University |
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HONG, HEE-JEON - University Of Cambridge |
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CHO, HYUNJI - Gyeongsang National University |
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KIM, DARAN - Gyeongsang National University |
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KWON, YOUNGHO - Gyeongsang National University |
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KWON, SOON-KYEONG - Yonsei University |
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CRUSEMANN, MAX - University Of California |
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LEE, YONG - Gyeongsang National University |
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KIM, JIHYUN - Yonsei University |
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GIAEVER, GURI - University Of British Columbia |
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NISLOW, COREY - University Of British Columbia |
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MOORE, BRADLEY - University Of California |
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Thomashow, Linda |
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Weller, David |
Submitted to: International PGPR Workshop
Publication Type: Abstract Only Publication Acceptance Date: 4/1/2015 Publication Date: N/A Citation: N/A Interpretive Summary: Technical Abstract: Crops lack genetic resistance to most necrotrophic pathogens. To compensate for this disadvantage, plants recruit antagonistic members of the soil microbiome to defend their roots against pathogens and other pests. The best examples of this microbe-based defense of roots are observed in disease-suppressive soils in which suppressiveness is induced by continuously growing crops that are susceptible to a pathogen, but the molecular basis of most is poorly understood. Here we report the microbial characterization of a Korean soil suppressive to Fusarium wilt of strawberry. In this soil, an attack on strawberry roots by Fusarium oxysporum results in a response by microbial defenders of which Streptomyces appears to be a key component. We also identify the Streptomyces genes responsible for the ribosomal synthesis of a novel heat-stable antifungal thiopeptide antibiotic inhibitory to F. oxysporum and the antibiotic’s mode of action against fungal cell wall biosynthesis. These results provide a framework for studies to elucidate the basis of microbe-based defense systems and soil suppressiveness from the field to the molecular level and highlight the role of natural antibiotics as weapons in the microbial warfare in the rhizosphere that is integral to plant health, vigor and development. |