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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Ruminant Diseases and Immunology Research » Research » Publications at this Location » Publication #330385
Title: Genetic diversity of bovine viral diarrhea virus in cattle from Mexico

Author
item GOMEZ-ROMERO, NINNET - Autonomous National University Of Mexico
item BASURTO-ALCANTARA, FRANCISCO - Autonomous National University Of Mexico
item VERDUGO-RODRIGUEZ, ANTONIO - Autonomous National University Of Mexico
item BAUERMANN, FERNANDO - Universidade Federal De Santa Maria
item Ridpath, Julia

Submitted to: Journal of Veterinary Diagnostic Investigation
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 12/9/2016
Publication Date: 4/4/2017
Publication URL: http://handle.nal.usda.gov/10113/5700672
Citation: Gomez-Romero, N., Basurto-Alcantara, F.J., Verdugo-Rodriguez, A., Bauermann, F.V., Ridpath, J.F. 2017. Genetic diversity of bovine viral diarrhea virus in cattle from Mexico. Journal of Veterinary Diagnostic Investigation. 29(3):362–365. doi: 10.1177/1040638717690187.

Interpretive Summary: Bovine viral diarrhea virus (BVDV) infections of cattle cause significant economic losses throughout the globe. BVDV strains can be divided into different groups termed species and subgenotypes. Differences between these groups results in vaccine and diagnostic failures. Previous studies have reported the prevalence of BVDV species and subgenotypes in cattle from the United States and Canada. In this study, we investigated the genetic diversity of BVDV strains detected in bovine serum samples from six different Mexican regions. In addition to the BVDV groups found in the United States and Canada, another group of BVDV was found in the samples from Mexico. These findings benefit the development of effective diagnostic assays, vaccines and control programs for North America.

Technical Abstract: Bovine viral diarrhea virus (BVDV) infects cattle populations worldwide causing significant economic losses though its impact in animal health. Previous studies have reported the prevalence of BVDV species and subgenotypes in cattle from the United States and Canada. In this study, we investigated the genetic diversity of BVDV strains detected in bovine serum samples from six different Mexican regions. Sixty-two bovine viral diarrhea viruses from Mexico were genetically typed based on comparison of sequences from the 5’unstranslated region (5’UTR) of the viral genome. Phylogenetic reconstruction indicated that 60 of the samples belonged to the BVDV-1 and 2 to the BVDV-2. Comparison of partial 5’UTR sequences clustered 49 samples within BVDV-1c, 8 samples within BVDV-1a, 3 samples within BVDV-1b, while two samples clustered with the BVDV-2a. This study combined with information previously published on BVDV field strain diversity in the United States and Canada benefits the development of effective diagnostic assays, vaccines and control programs for North America.