Author
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HARDIE, LYDIA - Iowa State University |
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VANDEHAAR, MICHAEL - Michigan State University |
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TEMPELMAN, ROB - Michigan State University |
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WEIGEL, KENT - University Of Wisconsin |
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ARMENTANO, LOU - University Of Wisconsin |
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WIGGANS, GEORGE - Former ARS Employee |
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VEERKAMP, ROEL - Collaborator |
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DE HAAS, YVETTE - Collaborator |
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COFFEY, MIKE - Scottish Agricultural College |
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Connor, Erin |
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HANIGAN, MARK - Virginia Polytechnic Institution & State University |
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STAPLES, CHARLIE - University Of Florida |
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WANG, Z - University Of Alberta |
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SPURLOCK, DIANE - Iowa State University |
Submitted to: Meeting Abstract
Publication Type: Other Publication Acceptance Date: 11/10/2016 Publication Date: 11/11/2016 Citation: Hardie, L., Vandehaar, M.J., Tempelman, R.J., Weigel, K.A., Armentano, L.E., Wiggans, G.R., Veerkamp, R.R., De Haas, Y., Coffey, M.P., Connor, E.E., Hanigan, M.D., Staples, C.R., Wang, Z., Spurlock, D.M. 2016. Exploration of the genetic and biological basis of feed efficiency in mid-lactation Holstein dairy cows. Multistate Project Meeting SCC84. November 11-16, 2016, Uppsala, Sweden. Interpretive Summary: Technical Abstract: The purpose of this study was to characterize the genetic basis underlying variation in feed efficiency in mid-lactation Holstein dairy cows. A genome-wide association study was performed for residual feed intake (RFI) and related traits using a large data set, consisting of nearly 5,000 cows. It was determined that RFI is a highly polygenic trait with many loci explaining a very small proportion of the genetic variance. The genetic basis of RFI and related traits may differ between primiparous and multiparous cows, and the genetic basis of feed efficiency is distinct from that underlying production and maintenance requirements. Two key candidate genes for RFI were indentified including beta-3 adrenergic receptor (ADRB3) among primiparous cows and leptin (LEP) in multiparous cows. |