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Submitted to: Veterinary Clinics of North America
Publication Type: Peer Reviewed Journal Publication Acceptance Date: 8/1/2017 Publication Date: 2/5/2018 Citation: Stegelmeier, B.L., Davis, T.Z. 2018. Toxic causes of intestinal disease in horses. Veterinary Clinics of North America. 34(1):127-139. https://doi.org/10.1016/j.cveq.2017.11.008. DOI: https://doi.org/10.1016/j.cveq.2017.11.008 Interpretive Summary: As most poisonings occur by toxin ingestion, the gastrointestinal system is first exposed and in most cases it is exposed to the highest toxin concentrations. Consequently stomach and intestine damage is common. However, as many toxins produce organ specific damage, and gastrointestinal damage is easily confused with post mortem change and many gastrointestinal lesions are overlooked or overshadowed by other clinical and pathologic changes. The objectives of this work is to review several common toxins and poisonous plants that produce primarily gastrointestinal disease. Technical Abstract: As most poisonings occur by toxin ingestion, the gastrointestinal system is first exposed and in most cases it is exposed to the highest toxin concentrations. Consequently enterocyte damage is common. However, as many toxins produce organ specific damage, and enterocyte necrosis is easily confused with autolysis, many gastrointestinal lesions are overlooked or overshadowed by other clinic and pathological changes. The objectives of this work is to review several common toxins and poisonous plants that produce primarily gastrointestinal disease. |
