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ARS Home » Southeast Area » Little Rock, Arkansas » Arkansas Children's Nutrition Center » Research » Publications at this Location » Publication #364654
Title: Perspective: Guiding principles for the implementation of personalized nutrition approaches that benefit health and function

Author
item Ferruzzi, Mario
item ANTHONY, JOSHUA - Campbell Soup Research
item CARVAJAL, RICARDO - Hyman, Phelps & Mcnamara, Pc
item CHAE, LEE - Brightseed
item KHOO, CHOR SAN - International Life Sciences Institute (ILSI)
item LATULIPPE, MARIE - International Life Sciences Institute (ILSI)
item MATUSHESKI, NATHAN - Dsm Nutritional Products, Ltd
item MCCLUNG, HOLLY - Us Army Medical Research Institute Of Infectious Diseases
item ROZGA, MARY - Academy Of Nutrition And Dietetics
item SCHMID, CHRISTOPHER - Brown University
item WOPEREIS, SUZAN - The Netherlands Organisation For Applied Scientific Research (TNO)
item YAN, WILLIAM - Health Canada

Submitted to: Advances in Nutrition
Publication Type: Review Article
Publication Acceptance Date: 7/22/2019
Publication Date: 8/29/2019
Citation: Adams, S.H., Anthony, J.C., Carvajal, R., Chae, L., Khoo, C., Latulippe, M.E., Matusheski, N.V., Mcclung, H.L., Rozga, M., Schmid, C.H., Wopereis, S., Yan, W. 2019. Perspective: Guiding principles for the implementation of personalized nutrition approaches that benefit health and function. Advances in Nutrition. https://doi.org/10.1093/advances/nmz086.
DOI: https://doi.org/10.1093/advances/nmz086

Interpretive Summary:

Technical Abstract: Personalized nutrition (PN) approaches have been shown to help drive behavior change and positively influence health outcomes. This has led to an increase in the development of commercially available PN programs, which utilize various forms of individual-level information to provide services and products for consumers. However, the lack of a well-accepted definition of PN or an established set of guiding principles for the implementation of PN creates barriers for establishing credibility and efficacy. To address these points, ILSI North America convened a multidisciplinary panel. In this paper, a definition for PN is proposed: Personalized nutrition uses individual-specific information, founded in evidence-based science, to promote dietary behavior change that may result in measurable health benefits. In addition, 10 guiding principles for PN approaches are proposed: 1) define potential users and beneficiaries; 2) use validated diagnostic methods and measures; 3) maintain data quality and relevance; 4) derive data-driven recommendations from validated models and algorithms; 5) design PN studies around validated health or function needs and outcomes; 6) provide rigorous scientific evidence for an effect on health or function; 7) deliver user-friendly tools; 8) for healthy individuals, align with population-based recommendations; 9) communicate transparently about potential effects; and 10) protect individual data privacy and act responsibly. These principles are intended to establish a basis for responsible approaches to the evidence-based research and practice of PN and serve as an invitation for further public dialogue. Several challenges were identified for PN to continue gaining acceptance, including defining the health-disease continuum, identification of biomarkers, changing regulatory landscapes, and accessibility. While PN approaches hold promise for public health in the future, further research is needed on the accuracy of dietary intake measurement, impacts of and variance around diet-lifestyle interactions (e.g., exercise and sedentary activity), utilization and standardization of systems approaches, and application and communication of evidence.