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Research Project: Intervention Strategies to Support the Global Control and Eradication of Foot-and-Mouth Disease Virus (FMDV)

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Title: Genome sequences of foot-and-mouth disease virus SAT 1 topotype X from Cameroon

Author
item BERTRAM, MIRANDA - Oak Ridge Institute For Science And Education (ORISE)
item DICKMU, SIMON - Lanavet
item Palinski, Rachel
item Pauszek, Steven
item Hartwig, Ethan
item Smoliga, George
item VIERRA, DAVID - Kansas State University
item ABDOULKADIRI, SOULEY - Lanavet
item Arzt, Jonathan

Submitted to: Microbiology Resource Announcements
Publication Type: Other
Publication Acceptance Date: 11/6/2019
Publication Date: 12/5/2019
Citation: Bertram, M.R., Dickmu, S., Palinski, R.M., Pauszek, S.J., Hartwig, E.J., Smoliga, G.R., Vierra, D., Abdoulkadiri, S., Arzt, J. 2019. Genome sequences of foot-and-mouth disease virus SAT 1 topotype X from Cameroon. Microbiology Resource Announcements. https://doi.org/10.1128/MRA.
DOI: https://doi.org/10.1128/MRA

Interpretive Summary: Foot-and-mouth disease virus (FMDV) is an important viral disease affecting animal health and economics through impacts on agriculture and trade. The disease has a large impact in Africa, where it is poorly controlled due to widespread unregulated movement of livestock and a lack of appropriate vaccines. Here we report the genome sequences of viruses from an outbreak in Cameroon in 2016. These viruses represent a novel strain that had not been previously identified in Cameroon. These genome sequences update the strains known to be circulating in Cameroon, which is important for regional disease control and to prevent virus spread to other regions.

Technical Abstract: We report the genomes of four foot-and-mouth disease virus (FMDV) serotype SAT 1 topotype X isolates from Cameroon. The viruses were isolated from bovine epithelium collected during an outbreak in 2016. These novel sequences update knowledge of FMDV diversity in Central Africa and contribute to regional FMDV molecular epidemiology.