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ARS Home » Southeast Area » Athens, Georgia » U.S. National Poultry Research Center » Exotic & Emerging Avian Viral Diseases Research » Research » Publications at this Location » Publication #372008
Research Project: Intervention Strategies to Prevent and Control Disease Outbreaks Caused by Emerging Strains of Avian Influenza Viruses

Location: Exotic & Emerging Avian Viral Diseases Research

Title: Low pathogenicity avian influenza (H5N2) viruses, Dominican Republic

Author
item CHUNG, HYUNJUNG - University Of Connecticut
item GOMEZ, DEJELIA - Ministry Of Agriculture
item VARGAS, JULIA - Ministry Of Agriculture
item AMADOR, BELKIS - Ministry Of Agriculture
item TORCHETTI, MIA - Animal And Plant Health Inspection Service (APHIS)
item KILLIAN, MARY - Animal And Plant Health Inspection Service (APHIS)
item Swayne, David
item LEE, DONG-HUN - University Of Connecticut

Submitted to: Emerging Infectious Diseases
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 8/21/2020
Publication Date: 12/1/2020
Citation: Chung, H., Gomez, D.R., Vargas, J.M., Amador, B.L., Torchetti, M.K., Killian, M.L., Swayne, D.E., Lee, D. 2020. Low pathogenicity avian influenza (H5N2) viruses, Dominican Republic. Emerging Infectious Diseases. 26(12):3094-3096. https://doi.org/10.3201/eid2612.200268.
DOI: https://doi.org/10.3201/eid2612.200268

Interpretive Summary: The first outbreak of mild form of H5N2 low pathogenic avian influenza virus (LPAIV) in Dominican Republic was reported in 2007 and re-emerged in 2017. We analyzed the genetic information for H5N2 LPAIV identified in Dominican Republic during 2007-2019 in the present study. These data supported a single introduction of Mexican-lineage H5N2 virus into poultry in Dominican Republic followed by divergence into three distinct genetic subgroups during 2007-2019. Genetic mutations over these 12 years may impact protection when using historic Mexican-lineage H5N2 vaccine strains.

Technical Abstract: Low pathogenicity avian influenza (H5N2) virus was detected in poultry in the Dominican Republic in 2007 and re-emerged in 2017. Whole-genome sequencing and phylogenetic analysis show introduction of an H5N2 virus lineage from Mexico into poultry in the Dominican Republic, then divergence into 3 distinct genetic subgroups during 2007–2019.