Genome sequences of 7 foot-and-mouth disease virus isolates reveal diversity in the O/ME-SA/Ind2001 lineage in India between

Authors: BERTRAM, MIRANDA - Oak Ridge Institute For Science And Education (ORISE); PALINSKI, RACHEL - US Department Of Agriculture (USDA); Pauszek, Steven; Hartwig, Ethan; Smoliga, George; BISWAL, JITENDRA - Icar-Indian Institute Of Maize Research; RANJAN, RAJEEV - Icar-Indian Institute Of Maize Research; SUBRAMANIAM, SARAVANAN - Icar-Indian Institute Of Maize Research; MOHAPATRA, JAJATI - Indian Council Of Agricultural Research (ICAR); Arzt, Jonathan; DAS, BISWAJIT - Indian Council Of Agricultural Research (ICAR); FISH, IAN - Oak Ridge Institute For Science And Education (ORISE); PATTANAIK, BRAMHADEV - Indian Council Of Agricultural Research (ICAR)

Submitted to: Microbiology Resource Announcements
Publication Type: Other
Publication Acceptance Date: 4/1/2020
Publication Date: 4/16/2020
Citation: Bertram, M., Palinski, R., Pauszek, S.J., Hartwig, E.J., Smoliga, G.R., Biswal, J.K., Ranjan, R., Subramaniam, S., Mohapatra, J.K., Arzt, J., Das, B., Fish, I.H., Pattanaik, B. 2020. Genome sequences of 7 foot-and-mouth disease virus isolates reveal diversity in the O/ME-SA/Ind2001 lineage in India between. Microbiology Resource Announcements. https://doi.org/10.1128/MRA.00287-20.
DOI: https://doi.org/10.1128/MRA.00287-20

Interpretive Summary: Foot-and-mouth disease virus (FMDV) is an important viral disease affecting animal health and economics through impacts on agriculture and trade. Most FMDV strains are typically limited to a particular geographical region; however few strains may spread beyond their typical range. These strains are concerning because of their potential to cause widespread outbreaks in many parts of the world or pandemics. The Ind2001d strain is an example of such strains. This strain originated in India and has spread throughout much of Asia in a relatively short time period. The 7 sequences reported here were collected in India just before and around the time the strain was emerging and include closely related strains. These sequences will be important for understanding FMDV evolution and for maintaining preparedness against the virus in FMDV-free regions such as USA.

Technical Abstract: We report the genomes of 7 FMD virus isolates collected in India during 1997-2009. The strains represented four sublineages within the O/ME-SA/Ind2001 lineage. These viruses provide insights into FMDV diversity and evolution in India, and may influence future control measures, including vaccine selections.