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ARS Home » Southeast Area » Little Rock, Arkansas » Arkansas Children's Nutrition Center » Microbiome and Metabolism Research » Research » Publications at this Location » Publication #375369
Research Project: Impact of Maternal Influence and Early Dietary Factors on Child Growth, Development, and Metabolic Health

Location: Microbiome and Metabolism Research

Title: The potential role of beef and nutrients found in beef on outcomes of wellbeing in healthy adults 50 years of age and older: A systematic review of randomized controlled trials

Author
item HAWLEY, AUBREE - University Of Arkansas
item LIANG, XINYA - University Of Arkansas
item BORSHEIM, ELISABET - University Arkansas For Medical Sciences (UAMS)
item WOLFE, ROBERT - University Arkansas For Medical Sciences (UAMS)
item SALISBURY, LUTISHOOR - University Of Arkansas
item WU, HEXIRUI - University Of Arkansas
item WALKER, SAM - University Of Arkansas
item TACINELLI, ANGELA - University Of Arkansas
item BAUM, JAMIE - University Of Arkansas

Submitted to: Meat Science
Publication Type: Review Article
Publication Acceptance Date: 4/18/2022
Publication Date: 4/21/2022
Citation: Hawley, A., Liang, X., Borsheim, E., Wolfe, R.R., Salisbury, L., Wu, H., Walker, S., Tacinelli, A.M., Baum, J.I. 2022. The effect of beef and beef's nutrients on well-being and quality of life in healthy adults >= 50 years to promote successful aging: A systematic review and meta-analysis of randomized control trials. Meat Science. https://doi.org/10.1016/j.meatsci.2022.108830.
DOI: https://doi.org/10.1016/j.meatsci.2022.108830

Interpretive Summary:

Technical Abstract: Shifts in quality of life and well-being commonly occur as we progress into old age. High quality protein sources, such as beef, are correlated with quality of life and well-being including physiological, cognitive function, mood, and quality of life outcomes. However, it is unclear how the combination of protein and other nutrients found in beef such as vitamin B-6, vitamin B-12, and zinc impact well-being and quality of life in healthy adults >= 50 years. The aim of this systematic review and meta- analysis was to evaluate the available evidence of randomized control trials (RCTs) assessing the effect of beef and beef's nutrients on quality of life and well-being in healthy adults = 50 years to promote successful aging. RCTs published before and up to September 30, 2019 were retrieved using PubMed, CINAHL, and Web of Science databases. Ten RCTs were included in the meta-analysis. The random-effects model indicated an overall positive effect of beef and beef's nutrients on quality of life and well-being (g = 0.17, 95% CI = [0.04, 0.30], p=0.01) with substantial heterogeneity (I2 78.8%). A significant positive effect of amino acids (g=1.53, 95% CI: [1.04, 2.03], p<0.01) and protein (g=0.71, 95% CI: [0.52, 0.92], p<0.01) was found with no effect of arginine, vitamin B-12, B-12 + B-6+ folic acid, leucine, and zinc with heterogeneity (p<0.05). Physical function (g=0.83, 95% CI: [0.49, 1.17], p<0.01) was significantly influenced by beef and beef's nutrients with heterogeneity (p<0.05). This evidence identified a need for further research to investigate the effect of isolated beef and nutrient's found in beef via homologous defined functional outcomes of well-being and quality of life to advance the research in the field of successful aging and nutrition.