Skip to main content
ARS Home » Research » Publications at this Location » Publication #378695
Research Project: Intervention Strategies to Support the Global Control and Eradication of Foot-and-Mouth Disease Virus (FMDV)

Location: Location not imported yet.

Title: Novel recombinant foot-and-mouth disease virus circulating in Vietnam

Author
item Bertram, Miranda
item BRITO, BARBARA - University Of Technology Sydney
item PALINSKI, RACHEL - University Of Kansas
item FISH, IAN - Oak Ridge Institute For Science And Education (ORISE)
item PAUSZEK, STEVEN - Animal And Plant Health Inspection Service (APHIS)
item Hartwig, Ethan
item Smoliga, George
item VU, LE - Dept Of Animal Health, Vietnam
item DUNG, DO - Dept Of Animal Health, Vietnam
item Arzt, Jonathan
item HOANG, BUI - Dept Of Animal Health, Vietnam
item PHUONG, NGUYEN - Dept Of Animal Health, Vietnam
item VU, PHAM - Dept Of Animal Health, Vietnam
item DUNG, NGUYEN - Dept Of Animal Health, Vietnam
item TIEN, NGUYEN - Dept Of Animal Health, Vietnam
item DONG, PHAM - Dept Of Animal Health, Vietnam

Submitted to: Microbiology Resource Announcements
Publication Type: Other
Publication Acceptance Date: 11/27/2020
Publication Date: 1/7/2021
Citation: Bertram, M.R., Brito, B., Palinski, R., Fish, I., Pauszek, S., Hartwig, E.J., Smoliga, G.R., Vu, L.T., Dung, D.H., Arzt, J., Hoang, B.H., Phuong, N.T., Vu, P.P., Dung, N.K., Tien, N.N., Dong, P.V. 2021. Novel recombinant foot-and-mouth disease virus circulating in Vietnam. Microbiology Resource Announcements. https://doi.org/10.1128/MRA.01263-20.
DOI: https://doi.org/10.1128/MRA.01263-20

Interpretive Summary: Foot-and-mouth disease virus (FMDV) is an important viral disease affecting animal health and economics through impacts on agriculture and trade. There are numerous different strains of FMDV, and vaccination or previous infection with one strain does not protect against infection with a different strain, so it is important to monitor which strains are causing outbreaks in an area. Additionally, recombination between different strains can create new strains that may be more likely to cause an outbreak. We report the genomes of a recombinant strain from Vietnam and emphasize the importance of sequencing the full genome in order to detect recombinant strains.

Technical Abstract: We report the genomes of 12 recombinant foot-and-mouth disease virus isolates from Vietnam. The recombinant strain has a capsid region from an A/Sea-97 strain, and non-structural segment from an O/ME-SA/PanAsia strain. The isolates were obtained from two outbreak samples collected in June 2017 and 10 subclinical samples collected 2017 – 2019.