The insecticidal activities of Erica manipuliflora Salisb. Extracts in the flowering and fruiting periods and their evaluation in term of chemical profiles of active extracts

Authors: SEN-UTSUKARCI, BUCRU - Istanbul University; GURDAL, BAHAR - Istanbul University; Estep Iii, Alden; Tabanca, Nurhayat; KURKCUOGLU, MINE - Anadolu Universtiy; GOGER, FATIH - Anadolu Universtiy; GUL, ZULFIYE - Istanbul University; BARDAKCI, HILAL - Acibadem University; BECNEL, JAMES - Retired ARS Employee; MAT, AFIFE - Istanbul University; CAN BASER, KEMAL HUSNU - Near East University

Submitted to: Asian Pacific Journal of Tropical Medicine
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 7/14/2022
Publication Date: 8/9/2022
Citation: Sen-Utsukarci, B., Gurdal, B., Estep Iii, A.S., Tabanca, N., Kurkcuoglu, M., Goger, F., Gul, Z., Bardakci, H., Becnel, J.J., Mat, A., Can Baser, K. 2022. The insecticidal activities of Erica manipuliflora Salisb. Extracts in the flowering and fruiting periods and their evaluation in term of chemical profiles of active extracts. Asian Pacific Journal of Tropical Medicine. 87:115380. https://doi.org/10.1016/j.indcrop.2022.115380.
DOI: https://doi.org/10.1016/j.indcrop.2022.115380

Interpretive Summary: Plant extracts and oils have been the major source of natural products with biological importance that can be used as alternative remedies for the treatment of infectious diseases or the control of insects that carry disease. Concerns about the toxicity of many synthetic insecticides and the development of resistance in insects require the development of new insecticides and repellents from isolated natural products. We conducted this study with the aim of finding naturally derived, safe, and easily obtainable natural products that could be used for mosquito control derived from Erica manipuliflora, a plant with broad usage in traditional Turkish medicine. We identified the compounds contained in different preparations and tested these compounds for insecticidal activity against mosquitoes. We identified several compounds with high insecticidal activity and potential for future characterization and development.

Technical Abstract: Aedes aegypti L. (Diptera: Culicidae) is an important vector of yellow fever, dengue and Zika fever. An increasing number of investigations of plant-based extracts, essential oils or phytochemicals have been conducted to discover effective pesticidal agents against Ae. aegypti. The investigations of Erica manipuliflora, especially its insecticidal activity is insufficient. This study was conducted to improve the knowledge about the activity of this species and to determine the insecticidal potential of different extracts from this plant in both flowering and fruiting periods. Five extracts exhibited mortality of greater than 90% and three exhibited low activity. The major volatile compounds of petroleum ether and acetone extracts of the plant in flowering and fruiting periods were found cyclopentanol (23.6%), methylcyclohexane (48.5%), 2-methyl-2-pentanol (31.28%), and 4-hydroxy-4-methyl-1,2-pentanone (32.6%), respectively. In LC-MS analysis, 5-O-caffeoylquinic acid, catechin, myricetin hexoside, myricetin rhamnoside and quercetin were found in the samples in both periods, while quinic acid, myricetin, myricetin pentoside, hibiscetin, quercetin glucuronide and gossypetin existed only in the flowering period samples, and quercetin rhamnoside and kaempferol rhamnoside only in the fruiting period samples. E. manipuliflora has potential for protection against vector-borne diseases and contains many insecticidal compounds in both periods.