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ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Virus and Prion Research » Research » Publications at this Location » Publication #384393
Research Project: Intervention Strategies to Control Influenza A Virus Infection in Swine

Location: Virus and Prion Research

Title: Streptococcus gallolyticus and bacterial endocarditis in swine, United States, 2015-2020

Author
item SITTHICHAROENCHAI, PANCHAN - IOWA STATE UNIVERSITY
item BURROUGH, ERIC - IOWA STATE UNIVERSITY
item Arruda, Bailey
item SAHIN, ORHAN - IOWA STATE UNIVERSITY
item DOS SANTOS, JESSICA - IOWA STATE UNIVERSITY
item MAGSTADT, DREW - IOWA STATE UNIVERSITY
item PINEYRO, PABLO - IOWA STATE UNIVERSITY
item SCHWARTZ, KENT - IOWA STATE UNIVERSITY
item RAHE, MICHAEL - IOWA STATE UNIVERSITY

Submitted to: Emerging Infectious Diseases
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 10/1/2021
Publication Date: 1/20/2022
Citation: Sitthicharoenchai, P., Burrough, E.R., Arruda, B.L., Sahin, O., Dos Santos, J.G., Magstadt, D.R., Pineyro, P.E., Schwartz, K.J., Rahe, M.C. 2022. Streptococcus gallolyticus and bacterial endocarditis in swine, United States, 2015-2020. Emerging Infectious Diseases. 28(1):192-195. https://doi.org/10.3201/eid2801.210998.
DOI: https://doi.org/10.3201/eid2801.210998

Interpretive Summary: In swine bacterial infections can affect valves in the heart causing a condition known as vegetative valvular endocarditis (VVE) which can result in death. Historically, these infections have been associated with several bacteria (Streptococcus suis, Erysipelothrix rhusiopathiae, and Trueperella pyogenes). Current information on the bacteria associated with swine VVE is lacking. In this study, a retrospective analysis of diagnostic case submissions to the Iowa State University Veterinary Diagnostic Laboratory from 2015-2020 was conducted to evaluate the trends in bacterial isolation from porcine cases of VVE. The bacteria recovered from cardiac valvular lesions were S. suis (55.06%), S. equisimilis (10.39%), S. gallolyticus (6.18%), other Streptococcus species (2.81%), E. rhusiopathiae (2.53%), Actinobacillus species (2.53%), T. pyogenes (0.84%), Enterococcus faecalis (0.56%), Vagococcus fluvialis (0.28%) and Staphylococcus aureus (0.28%). This is the first report of S. gallolyticus as a pathogen of pigs and causative agent of VVE.

Technical Abstract: In swine bacterial infections can affect valves in the heart causing a condition known as vegetative valvular endocarditis (VVE) which can result in death. Historically, these infections have been associated with several bacteria (Streptococcus suis, Erysipelothrix rhusiopathiae, and Trueperella pyogenes). Current information on the bacteria associated with swine VVE is lacking. In this study, a retrospective analysis of diagnostic case submissions to the Iowa State University Veterinary Diagnostic Laboratory from 2015-2020 was conducted to evaluate the trends in bacterial isolation from porcine cases of VVE. The bacteria recovered from cardiac valvular lesions were S. suis (55.06%), S. equisimilis (10.39%), S. gallolyticus (6.18%), other Streptococcus species (2.81%), E. rhusiopathiae (2.53%), Actinobacillus species (2.53%), T. pyogenes (0.84%), Enterococcus faecalis (0.56%), Vagococcus fluvialis (0.28%) and Staphylococcus aureus (0.28%). This is the first report of S. gallolyticus as a pathogen of pigs and causative agent of VVE.