Skip to main content
ARS Home » Midwest Area » Ames, Iowa » National Animal Disease Center » Infectious Bacterial Diseases Research » Research » Publications at this Location » Publication #384685
Research Project: Characterization of Antigens, Virulence Markers, and Host Immunity in the Pathogenesis of Johne’s Disease

Location: Infectious Bacterial Diseases Research

Title: Draft genome sequences of two Bison-type and two Sheep-type strains of Mycobacterium avium subspecies paratuberculosis

Author
item Bannantine, John
item Bayles, Darrell

Submitted to: Microbiology Resource Announcements
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 6/19/2021
Publication Date: 7/15/2021
Citation: Bannantine, J.P., Bayles, D.O. 2021. Draft genome sequences of two Bison-type and two Sheep-type strains of Mycobacterium avium subspecies paratuberculosis. Microbiology Resource Announcements. 10(28). Page 21. https://doi.org/10.1128/MRA.00526-21.
DOI: https://doi.org/10.1128/MRA.00526-21

Interpretive Summary: The publication reports the draft genome sequences of four novel Mycobacterium avium subspecies paratuberculosis strains. Two of these are bison-type strains that are rarely studied and two are sheep strains that are hard to culture. The four genome sequences were deposited in public sequence databases and are available to other researchers interested in studying the genome dynamics of this significant veterinary pathogen.

Technical Abstract: Genome sequences of two Type-B and two Type-S strains of Mycobacterium avium subsp. paratuberculosis are presented. These strains were isolated in the United States from sheep, bison and cattle suffering from Johne’s disease. These genomes will increase understanding of the minor differences that exist among this genetically stable subspecies.