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ARS Home » Pacific West Area » Parlier, California » San Joaquin Valley Agricultural Sciences Center » Commodity Protection and Quality Research » Research » Publications at this Location » Publication #392700
Research Project: New Approaches to Enhance Fresh Fruit Quality and Control Postharvest Diseases

Location: Commodity Protection and Quality Research

Title: Understanding resistance to anilinopyrimidine fungicides

Author
item Saito, Seiya
item Xiao, Chang-Lin

Submitted to: Book Chapter
Publication Type: Book / Chapter
Publication Acceptance Date: 3/18/2023
Publication Date: 9/25/2023
Citation: Saito, S., Xiao, C. 2023. Understanding resistance to anilinopyrimidine fungicides. Book Chapter. https://doi.org/10.19103/AS.2022.0116.13.
DOI: https://doi.org/10.19103/AS.2022.0116.13

Interpretive Summary: Anilinopyrimidines (AP) are a chemical class of fungicides that are effective against a broad range of fungal plant pathogens. Currently three fungicides (cyprodinil, mepanipyrim and pyrimethanil) belonging to this class are available in the market. In this book chapter, we provided up-to-date information on the mode(s) of action, mechanisms of resistance, fitness cost associated with AP resistance, current status and monitoring of AP resistance in various economic crops, and resistance management.

Technical Abstract: Anilinopyrimidines (AP) are a chemical class of fungicides that are effective against a broad range of phytopathogenic fungi. Cyprodinil, mepanipyrim and pyrimethanil belonging to this class are currently available in the market. Resistance to AP fungicides has been reported in various fungal species from many crops worldwide, and control failure has been reported in certain cases. Resistance to AP fungicides involves modifications in the target genes, efflux transporter related multi-drug resistance, or combination. Common resistance management practices such as limiting number of applications and alternations of fungicides with different modes of action classes may not suffice. Moreover, in recent years, resistance to multiple classes of fungicides, including APs, has developed and become prevalent in certain fungal pathogens. It is therefore essential to take into account various aspects of fungicide resistance of the target pathogens in order to develop tailored resistance management strategies and maintain efficacy of AP fungicides.