Nanofiber-based systems

Authors: LIU, FEI - Jiangnan University; MA, YUN - Jiangnan University; SARICAOGLU, FURKAN - Bursa Technical University; Chiou, Bor-Sen

Submitted to: Book Chapter
Publication Type: Book / Chapter
Publication Acceptance Date: 6/26/2023
Publication Date: 6/26/2023
Citation: Liu, F., Ma, Y., Saricaoglu, F.T., Chiou, B. 2023. Nanofiber-based systems. In Miao, M; Chen, L; McClements, D. Bioactive Delivery Systems for Lipophilic Nutraceuticals: Formulation, Fabrication, and Application. London: Royal Society of Chemistry. P 392-420. https://doi.org/10.1039/BK9781839165566-00392.
DOI: https://doi.org/10.1039/BK9781839165566-00392

Interpretive Summary: This book chapter describes the use of electrospun nanofibers for encapsulating bioactive compounds in packaging, medical, and pharmaceutical applications. Different electrospinning techniques are used to produce the encapsulated compounds. The chapter includes a description of the methods used to characterize the properties of the nanofibers. It also includes the different physical and chemical methods used to modify the nanofiber properties for specific controlled-release profiles.

Technical Abstract: Nanofibers have become one of the most important bioactive delivery systems since they have high surface area, high porosity and are considered safe. Phase separation, self-assembly, sol-gel methods, interfacial polymerization and electrospinning are commonly used for nanofibers fabrication. Among, electrospinning surpasses the other methods in terms of efficiency and has emerged as the most efficacious technique for producing nanofibers. This chapter describes the structural composition, physicochemical properties, adhesion mechanism, modification methods, advantages and disadvantages and application scope of nanofiber-based bioactive delivery systems.