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Research Project: Metabolic and Epigenetic Regulation of Nutritional Metabolism

Location: Children's Nutrition Research Center

Title: The duration, frequency, and volume of exclusive human milk and/or infant formula consumption and nutrient status: A systematic review

Author
item DEWEY, KATHRYN - University Of California, Davis
item BAZZANO, LYDIA - Tulane University
item DAVIS, TERESA - Children'S Nutrition Research Center (CNRC)
item DONOVAN, SHARON - University Of Illinois
item TAVERAS, ELSIE - Harvard Medical School
item KLEINMAN, RONALD - Harvard Medical School

Submitted to: Government Publication/Report
Publication Type: Review Article
Publication Acceptance Date: 7/15/2020
Publication Date: 7/15/2020
Citation: Dewey, K., Bazzano, L., Davis, T., Donovan, S., Taveras, E., Kleinman, R. 2020. The duration, frequency, and volume of exclusive human milk and/or infant formula consumption and nutrient status: A systematic review. Dietary Guidelines Advisory Committee Project. https://doi.org/10.52570/NESR.DGAC2020.SR0302.
DOI: https://doi.org/10.52570/NESR.DGAC2020.SR0302

Interpretive Summary:

Technical Abstract: Moderate evidence indicates that ever, compared with never, consuming human milk may be associated with fatty acid status from birth to 24 months. However, the difference in fatty acid status between infants fed human milk and infants fed infant formula is likely to depend on the composition of the human milk and infant formula consumed. Insufficient evidence is available to determine the relationship between ever, compared with never, consuming human milk and iron and zinc status from birth to 24 months. No evidence is available to determine the relationship between ever, compared with never, consuming human milk and iodine, vitamin B12, and vitamin D status from birth to 24 months. Insufficient evidence is available to determine the relationship between the duration of any human milk consumption, among infants fed human milk, and iron, zinc, vitamin D, and fatty acid status from birth to 24 months. No evidence is available to determine the relationship between the duration of any human milk consumption, among infants fed human milk, and iodine or vitamin B12 status from birth to 24 months. Insufficient evidence is available to determine the relationship between the duration of exclusive human milk consumption before the introduction of infant formula and fatty acid status. No evidence is available to determine the relationship between the duration of exclusive human milk consumption before the introduction of infant formula and iron, zinc, iodine, vitamin B12, or vitamin D status from birth to 24 months. No evidence is available to determine the relationship between the intensity, proportion, or amount of human milk consumed by mixed-fed infants and iron, zinc, iodine, vitamin B12, vitamin D, or fatty acid status from birth to 24 months.