Location: Jean Mayer Human Nutrition Research Center On Aging
Title: Adult vitamin D deficiency: fracture & fall preventionAuthor
DAWSON-HUGHES, BESS - Jean Mayer Human Nutrition Research Center On Aging At Tufts University | |
BISCHOFF-FERRARI, HEIKE - University Hospital Zurich |
Submitted to: Book Chapter
Publication Type: Book / Chapter Publication Acceptance Date: 7/7/2022 Publication Date: 12/15/2023 Citation: Dawson-Hughes, B., Bischoff-Ferrari, H.A. 2023. Adult vitamin D deficiency: fracture & fall prevention. In: Feldman and Pike's Vitamin D. 5th edition. Elsevier. https://doi.org/10.1016/B978-0-323-91338-6.00021-5. DOI: https://doi.org/10.1016/B978-0-323-91338-6.00021-5 Interpretive Summary: Technical Abstract: In this chapter, we summarize available evidence related to the impact of supplemental vitamin D on risk of falls and fractures in older adults. The goals are to identify the segment of the older adult population most likely to benefit from added vitamin D, to assess the association of a full range of circulating 25-hydroxyvitamin D levels with fall risk, to identify the dose and dose frequency most closely associated with reduced risk of falls and fractures, and to review the impact of vitamin D with and without supplemental calcium on risk of fractures. To address these goals, we draw heavily on evidence from individual randomized, controlled trials and on recent meta-analyses of these trials. |