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ARS Home » Plains Area » Clay Center, Nebraska » U.S. Meat Animal Research Center » Livestock Bio-Systems » Research » Publications at this Location » Publication #397762
Research Project: Applying Nutritional Strategies to Improve Early Embryonic Development and Progeny Performance in Beef Cows

Location: Livestock Bio-Systems

Title: Influence of estradiol on the uterine clock in cows and its relationship to fertility before and after timed artificial insemination

Author
item Cushman, Robert - Bob

Submitted to: Meeting Abstract
Publication Type: Other
Publication Acceptance Date: 11/30/2022
Publication Date: 1/17/2023
Citation: Cushman, R.A. 2023. Influence of estradiol on the uterine clock in cows and its relationship to fertility before and after timed artificial insemination. Cattle HQ. South Dakota State University/Episode 27:Unwinding the uterine clock. Online January 17, 2023.

Interpretive Summary:

Technical Abstract: Estradiol is the hormone that stimulates mating behavior in mammalian females. We have demonstrated that it influences uterine function and receptivity for the embryo. This study demonstrated that the circadian clock is disrupted in the uterus of cows that do not demonstrate mating behavior during a timed AI protocol. This disruption leads to irregular reproductive cycles that cause these cows to have decreased fertility even when placed with the clean-up bulls. If behavioral estrus and fertility is poor when using timed-AI it can lead to a situation where fertility of the cow herd to the clean-up bulls is poor also, not because the hormonal synchronization did not work or something damaging but because the uterine clock is disrupted by improper steroid priming.