New high performance hydroxylpropyl methyl cellulose films using amylose inclusion complexes

Authors: Selling, Gordon

Submitted to: American Chemical Society National Meeting
Publication Type: Abstract Only
Publication Acceptance Date: 3/28/2023
Publication Date: 3/28/2023
Citation: Selling, G.W. 2023. New high performance hydroxylpropyl methyl cellulose films using amylose inclusion complexes. American Chemical Society National Meeting. [abstract].

Interpretive Summary:

Technical Abstract: When high amylose (70% amylose) corn starch, is gelatinized in the presence of hydrophobic ligands, an amylose inclusion complex (AIC) can form. With cooling, the amylose component wraps around the ligand to form the AIC. The AICs used were composed of 95% starch and 5% ligand. The starch or ligand on its own will not form a water solution - they may go into solution when hot, but on cooling they will either form a gel or a precipitate. However, when the two components are combined and form an AIC, they form a colloidal suspension and stay in solution. AICs formed from fatty sodium salts or fatty ammonium salts were found to be effective at modifying the properties of cellulosic films. Hydroxypropyl methylcellulose (HPMC) is a widely used water soluble cellulosic polymer. Its value can be increased by blending it with AICs. The properties of the HPMC / AIC blended films is dependent on the ratio of each component used and which charged ligand is used. When fatty acid salt AICs are used, they provide higher value films with a better balance of physical properties, and decreased gas permeability. When fatty ammonium salt AICs are used, the blended films have decreased gas permeability and they have an anti-microbial surface. The incorporation of readily made inexpensive AICs into HPMC provide a novel inexpensive route to increase the value of HPMC films.