Brassinosteroid biosynthesis and signaling: conserved and diversified functions of core genes across multiple plant species

Authors: ZEBOSI, BRIAN - Iowa State University; VOLLBRECHT, ERIK - Iowa State University; Best, Norman

Submitted to: Plant Communications
Publication Type: Review Article
Publication Acceptance Date: 5/28/2024
Publication Date: 7/8/2024
Citation: Zebosi, B., Vollbrecht, E., Best, N.B. 2024. Brassinosteroid biosynthesis and signaling: conserved and diversified functions of core genes across multiple plant species. Plant Communications. https://doi.org/10.1016/j.xplc.2024.100982.
DOI: https://doi.org/10.1016/j.xplc.2024.100982

Interpretive Summary: N/A

Technical Abstract: Brassinosteroids (BRs) are important regulators that control myriad aspects of plant growth and development, including biotic and abiotic stress responses, such that modulating BR homeostasis and signaling presents abundant opportunities for plant breeding and crop improvement. Enzymes and other proteins involved in the biosynthesis and signaling of BRs are well understood from molecular genetics and phenotypic analysis in Arabidopsis thaliana; however, knowledge of the molecular functions of these genes in other plant species, especially cereal crop plants, is minimal. In this manuscript, we comprehensively review functional studies of BR genes in Arabidopsis, maize, rice, Setaria, Brachypodium, and soybean to identify conserved and diversified functions across plant species and to highlight cases for which additional research is in order. We performed pylogenetic analysis of gene families involved in the biosynthesis and signaling of BRs and re-analyzed publicly available transcriptomic data. Gene trees coupled with expression data provide a valuable guide to supplement future research on BRs in these important crop species, enabling researchers to identify gene-editing targets for BR-related functional studies.