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ARS Home » Northeast Area » Beltsville, Maryland (BARC) » Beltsville Agricultural Research Center » Animal Biosciences & Biotechnology Laboratory » Research » Publications at this Location » Publication #404132
Research Project: Alternatives to Antibiotics Strategies to Control Enteric Diseases of Poultry

Location: Animal Biosciences & Biotechnology Laboratory

Title: Editorial; immunosuppressive diseases in poultry

Author
item Li, Charles
item WANG, LEYI - University Of Illinois
item ZHANG, SHIJUN - China Agricultural University

Submitted to: Frontiers in Immunology
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 5/26/2023
Publication Date: 6/12/2023
Citation: Li, C.Z., Wang, L., Zhang, S. 2023. Editorial; immunosuppressive diseases in poultry. Frontiers in Immunology. 14:1215513. https://doi.org/10.3389/fimmu.2023.1215513.
DOI: https://doi.org/10.3389/fimmu.2023.1215513

Interpretive Summary: Some pathogens and fungal toxins may damage the immune systems and cause suboptimal immune responses of the hosts to the secondary infections (immune suppression) in the chickens, therefore increasing mortalities, reducing feed conversion and vaccine effectiveness, and increasing total poultry production cost. On the other hand, pathogens may evolve complex mechanisms to evade the host immunity (immune evasion). Understanding the pathogenesis of immunosuppressive diseases is crucial to preventing / controlling these diseases and safeguarding poultry health and productivity in the poultry industry. This editorial summary highlights the four-selected articles published in the journal entitled “Frontiers in Immunology” which share the latest knowledge and progresses of molecular mechanism of immune suppression and evasion on the research topic of immune-suppressive diseases in poultry.

Technical Abstract: Immunosuppressive diseases, resulting from damage to the immune systems by pathogens and environmental/nutritional stressors, can increase susceptibility to secondary infections and mortalities, reduce feed conversion and vaccine effectiveness, and negatively impact the total poultry production cost. This editorial, on the research topic of immunosuppressive diseases in poultry, summarized the four selected articles in keeping the readers abreast of the latest knowledge and progress of virus-mediated immunosuppression and immunoevasion, breeding for disease-resistant chicken line, and the vaccine development on Eimeria parasites. Understanding the pathogenesis of immunosuppressive diseases is crucial to controlling these diseases and safeguarding health and productivity in the poultry industry.