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ARS Home » Midwest Area » Columbia, Missouri » Biological Control of Insects Research » Research » Publications at this Location » Publication #409413
Research Project: Biologically-Based Products for Insect Pest Control and Emerging Needs in Agriculture

Location: Biological Control of Insects Research

Title: iSalivaomicDB: a comprehensive saliva omics database for insects

Author
item ZHANG, BO - Zhejiang University
item CHEN, LONGFEI - Zhejiang University
item XIAO, SHAN - Zhejiang University
item DANG, CONG - Hangzhou Normal University
item WANG, FANG - Zhejiang University
item FANG, QI - Zhejiang University
item YE, XINHAI - Zhejiang University
item Stanley, David
item YE, GONGYIN - Zhejiang University

Submitted to: Insect Science
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 2/5/2024
Publication Date: 3/7/2024
Citation: Zhang, B., Chen, L., Xiao, S., Dang, C., Wang, F., Fang, Q., Ye, X., Stanley, D.W., Ye, G. 2024. iSalivaomicDB: a comprehensive saliva omics database for insects. Insect Science. https://doi.org/10.1111/1744-7917.13349.
DOI: https://doi.org/10.1111/1744-7917.13349

Interpretive Summary: Over the last two decades, advances in modern biological research tools have led to recording tremendous amounts of data. One example is human genome project, which started in 1990 and was completed in 2003. This project was the first of its kind with a goal of generating the first full sequence of all the genes in a human. It was a 13-year, $2.7 million dollar project. Now it is common to generate the sequence of an entire animal or plant genome in under 12 hours at a cost of less than $1,000. The powerful analytical tools generate astonishing amounts of data. Yet, scientists cannot make sense of the data without equally astonishing data management tools. Various databases make up one data management tool. There are now over 5,000 biological databases scientists routinely use in research. Here, we report on a new database focused on the many proteins in insect saliva. Scientists around the world will draw on this database to support research into several important areas of insect science. These include insect pest management and how mosquitoes and ticks transmit diseases. This database will help scientists develop new pest management technologies that will lead to meaningful reductions in insect- and tick-transmitted human diseases and crop losses to insect damage. Ultimately, the database will help improve global human health and food security.

Technical Abstract: Insect saliva acts in a wide range of physiological pathways. Because of its broad biological roles, saliva functions as a vital vector to transmit human and plant pathogenic viruses. The development of highly efficient biological research instruments, such as mass spectrometry and high-throughput sequencing in recent years led to a substantial increase in the amount of global biological data. Here, the same point applies to identification of insect saliva components. Here, we provide a systematic and detailed saliva omics database, iSalivaomic, to support scientific research. The iSalivaomic database, offers protein query and analysis services for insect salivary proteins, including 1905 salivary proteins, 34 genomes, 29 proteomes, and 93 transcriptomes from 59 species. The protein analysis shows that all salivary protein families, and the positions of the salivary proteins on chromosomes. This database provides data support and bioinformatic analysis to explore the molecular components of saliva for use in biological research.